KEGG   Rattus norvegicus (rat): 287379
Entry
287379            CDS       T01003                                 
Symbol
Shmt1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00260  Glycine, serine and threonine metabolism
rno00630  Glyoxylate and dicarboxylate metabolism
rno00670  One carbon pool by folate
rno01100  Metabolic pathways
rno01200  Carbon metabolism
rno01230  Biosynthesis of amino acids
rno01240  Biosynthesis of cofactors
rno01523  Antifolate resistance
Module
rno_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    287379 (Shmt1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    287379 (Shmt1)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    287379 (Shmt1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    287379 (Shmt1)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     287379 (Shmt1)
SSDB
Motif
Pfam: SHMT Aminotran_1_2
Other DBs
NCBI-GeneID: 287379
NCBI-ProteinID: NP_001400080
RGD: 1312011
Ensembl: ENSRNOG00000005275
Position
10:complement(45968959..45990341)
AA seq 478 aa
MAERDATVWASHEKMLTQPLKESDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALG
SCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYHLDPQCWGVNVQPYSGSPANFA
VYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPDTGYINYDQL
EENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFE
HCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGEETYYELESLINSAVFPGLQGGPHN
HAIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRPK
GTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKIAHFIH
RGIELTLQIQSHMTMRATLKEFKEKLTGDEKFQSAVAALREEVENFASNFSLPGLPDF
NT seq 1437 nt   +upstreamnt  +downstreamnt
atggcagagagggatgccaccgtgtgggcctctcatgagaagatgttgacacagcccctg
aaggagagcgatgctgaggtttacagcatcattaaaaaggagagcaaccggcagagggtc
ggattggagctgattgcctcggagaactttgccagcagagctgtgttggaggccctagga
tcttgcttaaataacaaatactctgaggggtacccaggccaaaggtattatggtgggact
gagttcatcgatgagctggagacgctgtgtcagaagcgtgcattacaggcctaccatctg
gatcctcagtgctggggcgtcaatgtccagccttattcaggctcccctgcaaactttgct
gtgtatactgccctagtagagccccatgggcgaatcatgggtttggacctgccagatggt
ggccatctgactcatggcttcatgacagacaagaagaaaatctctgccacctctatcttc
tttgaatccatgccttataaggtatacccagacactgggtacatcaactatgaccagcta
gaggagaatgccagcctcttccacccgaagctgatcattgcagggaccagctgctactcc
cggaacctggactatgcgcggctgcgaaagattgcggatgataatggggcatatctcatg
gcagacatggcacacatcagtgggctcgtggcagctggtgtggtgccctcaccctttgaa
cactgtcatgtagtaaccactacaacccacaagaccctgagaggctgccgtgctggtatg
atattctacagaaagggtgtgcgcagtgttgatcccaagactggcgaagagacttactat
gaactggagtccctcatcaactcggccgtgttcccaggcctgcagggcggccctcacaac
catgccattgctggtgttgctgtggccctgaagcaagccatgactacagaattcaaaatc
taccagctccaggtgttggccaactgcagggctctgtctgatgcactcacagagctaggc
tacaaaatagtcacaggtggctctgataatcacttgatcctaatggatctgcgtcctaag
ggtactgatggcggaagggctgagaaggtactggaagcctgttctatcgcctgcaacaag
aatacctgcccaggtgacaagagtgcgttacggcccagtggcctgcgactgggaactcca
gcattgacatcccgaggacttttggaagaagacttccaaaaaatagcacactttatccac
agagggatagagttgactctgcagattcagagccacatgaccatgagggccacactgaaa
gagttcaaggagaagctgacaggggatgagaagttccagagtgctgtggcagctctccgg
gaagaagtggagaattttgcttccaacttctcactacctggacttcctgacttctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (44)   

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