KEGG   Rattus norvegicus (rat): 291283
Entry
291283            CDS       T01003                                 
Symbol
Akr1c2
Name
(RefSeq) aldo-keto reductase family 1 member C21
  KO
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno00980  Metabolism of xenobiotics by cytochrome P450
rno01100  Metabolic pathways
rno05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    291283 (Akr1c2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    291283 (Akr1c2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    291283 (Akr1c2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149  20alpha-hydroxysteroid dehydrogenase
     291283 (Akr1c2)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     291283 (Akr1c2)
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.20  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
     291283 (Akr1c2)
SSDB
Motif
Pfam: Aldo_ket_red DMAP1_like
Other DBs
NCBI-GeneID: 291283
NCBI-ProteinID: NP_001013075
RGD: 1311841
Ensembl: ENSRNOG00000029844
UniProt: Q6AYQ2
Position
17:complement(70669684..70717935)
AA seq 318 aa
MNSKCHCVKLNDGHFIPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDH
VGEAIREKIANGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPM
ALKPGDENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKP
GLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPV
LSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMKLSPEDMKVLDDLNRNLRY
IAGGIFEGHPNFPFLDEY
NT seq 957 nt   +upstreamnt  +downstreamnt
atgaactccaaatgtcattgtgtgaaactgaacgatggtcatttcattccggtgctgggt
tttggaactgctatgccttcagagttacccaagagtaaagctaaggaggtcaccaaaata
gctatagatgctggtttccatcattttgattctgcttttgtctacaataccgaagatcat
gtaggagaggccatccgagagaagattgccaatggcactacaaggagagaagatatattt
tacacatcaaagctttggtgtacgagccttcacccagaactggtgagatcttccttggaa
tgttcactgaagaaacttcagttggactatgtggacctgtatctcatacattttccgatg
gccttgaaaccaggagatgaaaattttccagtagatgaacatggaaagttactatttgac
acagtagatctctgtgctacctgggaggccatggagaagtgtaaggatgcaggactggcc
aagtccatcggggtgtccaactttaaccgcaggcagctggagaagatcctgaacaagccg
gggctcaaatacaagcctgtgtgcaaccaggtagaatgccatctttatctcaaccaaatg
aaactgctggatttctgcaagacaaatggcattatactggttgcctatggagttctggga
acacaacgatataacggatgggtagaccagaactcccctgttctcttgaatgaaccagtt
cttagttccatggcaaaaaaatacaatcaaactccagccttgattgcccttcgccatcag
ttgcagcgtgggattgtggtacttaacaccagtctcaaagaagagcggatcaaagagaac
atgaagctgagtccagaagatatgaaagtccttgatgacctgaacagaaatttgcggtac
atagctggtggaatatttgaaggccaccctaattttccgtttttggatgaatactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (17)   
   KEGG COMPOUND (17)   
Chemical reaction (10)   
   KEGG ENZYME (3)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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