KEGG   Rattus norvegicus (rat): 291450
Entry
291450            CDS       T01003                                 
Symbol
Aldh7a1
Name
(RefSeq) alpha-aminoadipic semialdehyde dehydrogenase
  KO
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00010  Glycolysis / Gluconeogenesis
rno00053  Ascorbate and aldarate metabolism
rno00071  Fatty acid degradation
rno00260  Glycine, serine and threonine metabolism
rno00280  Valine, leucine and isoleucine degradation
rno00310  Lysine degradation
rno00330  Arginine and proline metabolism
rno00340  Histidine metabolism
rno00380  Tryptophan metabolism
rno00410  beta-Alanine metabolism
rno00561  Glycerolipid metabolism
rno00620  Pyruvate metabolism
rno01100  Metabolic pathways
rno04936  Alcoholic liver disease
Module
rno_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
rno_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA
rno_M00555  Betaine biosynthesis, choline => betaine
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    291450 (Aldh7a1)
   00053 Ascorbate and aldarate metabolism
    291450 (Aldh7a1)
   00620 Pyruvate metabolism
    291450 (Aldh7a1)
  09103 Lipid metabolism
   00071 Fatty acid degradation
    291450 (Aldh7a1)
   00561 Glycerolipid metabolism
    291450 (Aldh7a1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    291450 (Aldh7a1)
   00280 Valine, leucine and isoleucine degradation
    291450 (Aldh7a1)
   00310 Lysine degradation
    291450 (Aldh7a1)
   00330 Arginine and proline metabolism
    291450 (Aldh7a1)
   00340 Histidine metabolism
    291450 (Aldh7a1)
   00380 Tryptophan metabolism
    291450 (Aldh7a1)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    291450 (Aldh7a1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    291450 (Aldh7a1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3  aldehyde dehydrogenase (NAD+)
     291450 (Aldh7a1)
    1.2.1.8  betaine-aldehyde dehydrogenase
     291450 (Aldh7a1)
    1.2.1.31  L-aminoadipate-semialdehyde dehydrogenase
     291450 (Aldh7a1)
SSDB
Motif
Pfam: Aldedh DUF1487
Other DBs
NCBI-GeneID: 291450
NCBI-ProteinID: NP_001258034
RGD: 1308614
Ensembl: ENSRNOG00000014645
UniProt: Q64057 A6IX60
Position
18:complement(52208035..52240293)
AA seq 539 aa
MLRLARPLCVQTVKASKLSRLWSRPAALMSTLLIHHPQYAWLQDLGLREDNEGVFNGSWG
GRGEVITTYCPANNEPIARVRQASMKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDA
LREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALME
QWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSIAVTKIIAKVLED
NLLPGAICSLTCGGADMGTAMARDERVNLLSFTGSTQVGKQVALMVQERFGKSLLELGGN
NAIIAFEDADLSLVLPSALFAAVGTAGQRCTTVRRLFLHESIHDEVVDRLKNAYSQIRVG
NPWDPNILYGPLHTKQAVSMFVQAVEEAKKEGGTVVYGGKVMDHPGNYVEPTIVTGLVHD
APIVHKETFAPILYVFKFKNEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTALPLAQGIKFQ
NT seq 1620 nt   +upstreamnt  +downstreamnt
atgttgcgtctggctcgcccgctctgcgtgcagactgtgaaggccagcaaactttcccgc
ctttggagtaggcctgccgcccttatgtctactctgctgatccatcatccccagtatgcc
tggctgcaagacctgggtctccgcgaagataacgagggcgtgtttaatggaagctggggc
ggccggggagaggtaattacgacctattgtcctgctaacaatgagccaatagcaagagtc
cgacaggccagcatgaaagactatgaagagactatagggaaagccaagaaagcttggaac
atctgggcagatattcctgccccaaagcgaggagaaatagtcagaaagattggcgatgcc
ttgcgggagaagatccaattactgggaagactggtgtctttggagatggggaaaatctta
gtggaaggaataggggaggttcaggagtacgtggacgtctgcgattatgctgccggcttg
tcgaggatgatcgggggacccaccttgccctctgaaagacccggccatgctctcatggaa
cagtggaatccgttaggcctggtgggaatcatcactgccttcaacttccctgtggctgtg
tttggctggaacaatgccatagctctgatcacaggcaacgtctgcctttggaaaggagca
ccaacaacttccctcgttagtatagctgtcacaaagatcatagccaaggttttggaggac
aacctgctgcctggtgccatttgctccctgacctgtggtggagcagatatgggcacagca
atggccagagatgagcgtgtgaacctgctgtcgttcactgggagcactcaggtggggaag
caggtggccctcatggtgcaggagaggtttgggaaaagcttgttggagctcggaggaaac
aatgccatcattgctttcgaggacgccgacctcagcttggttcttccctccgctctgttt
gccgccgtgggaacagccggccagaggtgtaccactgtgaggcgactgtttttgcacgaa
agcatccatgatgaagttgtagacagactgaaaaatgcctactcacagatccgtgtcggg
aacccctgggaccccaatatcctctatggaccgctccacaccaaacaggcggtgagcatg
tttgtgcaagccgtggaagaagcaaagaaagaaggaggcacggtggtctatgggggcaag
gtcatggaccaccctggcaattatgtggaacccaccattgtgactggtcttgtccatgat
gcgcccattgttcacaaggagacttttgccccaattctctatgtcttcaaattcaagaat
gaagaagaggtctttgaatggaacaatgaagtaaaacagggactttcgagtagtatcttt
accaaggatctgggcagaatcttccgctggcttggacctaagggttcagactgtggcatt
gtgaacgtcaatattcctaccagcggggctgagatcggcggtgcgtttggaggcgagaag
cacacgggcggtggcagggaatctggcagcgatgcctggaagcagtacatgcggagatct
acgtgtaccatcaactacagcacggccctccctctggctcaaggtatcaagtttcagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (17)   
   KEGG PATHWAY (14)   
   KEGG MODULE (3)   
Chemical substance (38)   
   KEGG COMPOUND (38)   
Chemical reaction (22)   
   KEGG ENZYME (3)   
   KEGG REACTION (19)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (97)   

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