KEGG   Rattus norvegicus (rat): 29224
Entry
29224             CDS       T01003                                 
Symbol
Cbr1
Name
(RefSeq) carbonyl reductase [NADPH] 1
  KO
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00590  Arachidonic acid metabolism
rno00790  Folate biosynthesis
rno00980  Metabolism of xenobiotics by cytochrome P450
rno01100  Metabolic pathways
rno05204  Chemical carcinogenesis - DNA adducts
rno05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    29224 (Cbr1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    29224 (Cbr1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    29224 (Cbr1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    29224 (Cbr1)
   05208 Chemical carcinogenesis - reactive oxygen species
    29224 (Cbr1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.184  carbonyl reductase (NADPH)
     29224 (Cbr1)
    1.1.1.189  prostaglandin-E2 9-reductase
     29224 (Cbr1)
    1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)
     29224 (Cbr1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase Polysacc_synt_2
Other DBs
NCBI-GeneID: 29224
NCBI-ProteinID: NP_062043
RGD: 2286
Ensembl: ENSRNOG00000049911
Vega: OTTRNOG00000000866
UniProt: P47727
Position
11:46346405..46348815
AA seq 277 aa
MSSDRPVALVTGANKGIGFAIVRDLCRKFLGDVVLTARDESRGHEAVKQLQTEGLSPRFH
QLDIDNPQSIRALRDFLLQEYGGLNVLVNNAGIAFKVVDPTPFHIQAEVTMKTNFFGTQD
VCKELLPIIKPQGRVVNVSSSVSLRALKSCSPELQQKFRSETITEEELVGLMNKFVEDAK
KGVHAKEGWPNSAYGVTKIGVTVLSRIYARKLTEERREDKILLNACCPGWVRTDMAGPKA
TKSPEEGAETPVYLALLPPGAEGPHGQFVQDKKVEPW
NT seq 834 nt   +upstreamnt  +downstreamnt
atgtcttccgacagacccgtggcactggtgactggtgctaacaaaggaatcggattcgcg
atcgtacgtgatctctgtcgtaaattcttgggggacgtggtcctcacggcgcgggacgag
tcacggggccacgaggcggtgaagcagctgcagaccgagggcctgagcccacgcttccac
cagctggacatcgacaacccgcagagcatccgcgcgctgcgtgactttctgcttcaggag
tacggaggactgaacgtgctggtcaacaatgcgggcatcgccttcaaagttgttgacccc
acccccttccacattcaagcagaggtgacaatgaaaaccaacttttttggtacccaagat
gtctgcaaggagctactccctataataaaaccccaaggcagagtggtgaatgtatcaagc
agcgtgagtctcagggccctgaaaagctgcagcccggagctgcagcagaagtttcgaagt
gagaccatcactgaggaagagctggtggggctcatgaacaagtttgtagaggatgcaaag
aaaggagtccatgcgaaagaaggctggcccaatagtgcatatggggtcaccaagataggg
gtgacagtcctgtccagaatctatgccaggaaactcactgaggagaggagagaggacaag
atcctcctgaatgcctgctgccctgggtgggtcagaaccgacatggcaggaccaaaagcc
accaaaagcccagaagaaggagcagagacccccgtgtacttggcccttttgcctccaggt
gcagaggggcctcacgggcagtttgttcaagataaaaaagttgaaccatggtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (5)   
   Pfam (5)   
All databases (51)   

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