KEGG   Rattus norvegicus (rat): 29230
Entry
29230             CDS       T01003                                 
Symbol
Sqle
Name
(RefSeq) squalene monooxygenase
  KO
K00511  squalene monooxygenase [EC:1.14.14.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00100  Steroid biosynthesis
rno01100  Metabolic pathways
Module
rno_M00101  Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    29230 (Sqle)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.17  squalene monooxygenase
     29230 (Sqle)
SSDB
Motif
Pfam: SE FAD_binding_3 DAO NAD_binding_8 Pyr_redox FAD_binding_2 TrkA_N Pyr_redox_2 NAD_Gly3P_dh_N Sacchrp_dh_NADP 3HCDH_N ApbA AlaDh_PNT_C GIDA Shikimate_DH F420_oxidored NAD_binding_2 Lipoprotein_21 FAD_oxidored
Other DBs
NCBI-GeneID: 29230
NCBI-ProteinID: NP_058832
RGD: 3755
Ensembl: ENSRNOG00000009550
UniProt: P52020 A6HRM0
Position
7:92758175..92773049
AA seq 573 aa
MWTFLGIATFTYFYKKCGDVTLANKELLLCVLVFLSLGLVLSYRCRHRNGGLLGRHQSGS
QFAAFSDILSALPLIGFFWAKSPPESEKKEQLESKRRRKEVNLSETTLTGAATSVSTSSV
TDPEVIIIGSGVLGSALATVLSRDGRTVTVIERDLKEPDRILGECLQPGGYRVLRELGLG
DTVESLNAHHIHGYVIHDCESRSEVQIPYPVSENNQVQSGVAFHHGKFIMSLRKAAMAEP
NVKFIEGVVLRLLEEDDAVIGVQYKDKETGDTKELHAPLTVVADGLFSKFRKNLISNKVS
VSSHFVGFIMKDAPQFKANFAELVLVDPSPVLIYQISPSETRVLVDIRGELPRNLREYMT
EQIYPQIPDHLKESFLEACQNARLRTMPASFLPPSSVNKRGVLLLGDAYNLRHPLTGGGM
TVALKDIKIWRQLLKDIPDLYDDAAIFQAKKSFFWSRKRSHSFVVNVLAQALYELFSATD
DSLRQLRKACFLYFKLGGECLTGPVGLLSILSPDPLLLIRHFFSVAVYATYFCFKSEPWA
TKPRALFSSGAILYKACSIIFPLIYSEMKYLVH
NT seq 1722 nt   +upstreamnt  +downstreamnt
atgtggacttttcttggaattgctactttcacctatttttataagaaatgcggggatgtc
accctggccaacaaggagctcctgctgtgcgtactggtgttcctgtcgctgggcctggtg
ctctcctaccgctgtcgccatcgaaacgggggcctccttggccgccatcagagcggctcc
cagttcgctgccttctcagatattctctctgctttgcctcttattggcttcttctgggcc
aaatcaccccctgaatcagaaaagaaagaacagctggagtccaagaggcgcagaaaagaa
gtcaatctgtcagagacgacgttaacgggagcagctacctcagtatcgacatcatctgtg
acggacccagaagtgatcatcatagggtctggtgtacttggctctgctttggcaacagta
ctctctagagatggaagaacggtgacagtaatcgagagagatttaaaagagcctgacaga
atacttggagagtgtctgcagcccggtggctatcgagttcttcgagagctgggccttgga
gatacagtagaaagtcttaatgcccatcatatacacggctacgtaattcatgactgtgaa
agcaggtctgaagttcaaattccatacccggtgtcagaaaacaaccaagtacagagtggg
gttgctttccaccatggcaagttcatcatgagtctccggaaagcagctatggcagagccc
aatgtaaagtttatagaaggtgttgtgcttcggttactagaggaagatgatgctgtgatt
ggtgtgcaatacaaggacaaggagactggggacaccaaggagctccatgccccgctcact
gttgttgccgacgggctcttctccaagttcaggaagaacctcatctccaataaagtctct
gtttcctcccacttcgttggcttcattatgaaggatgcaccacagtttaaagccaatttc
gcggagcttgttctggtcgatcccagtccagttctcatctaccagatttcacccagcgaa
actagggtgcttgtcgatattcgaggagaattgccaagaaacttaagagaatacatgaca
gaacaaatttacccacagatacctgatcacttgaaggaatcatttctggaggcctgtcag
aatgctcgtctgcggaccatgccagcaagcttccttcctccttcctcagtgaacaaacga
ggcgtcctacttctgggagatgcgtataacctgaggcatcctcttactggtggaggaatg
acagtcgctttaaaagatataaaaatatggagacaactgttaaaagatattcctgacctt
tatgatgatgccgctattttccaggccaaaaagtcattcttttggtcaagaaaaaggagc
cattcctttgttgtgaacgtgctggctcaggcgttgtatgaactattttctgctacagat
gattccttgcgtcagctccgaaaagcttgctttctttattttaaacttggtggagaatgt
ttgactggtcctgttgggttgctttctatattgtctcctgaccctctcctattgattcga
cacttcttctccgttgcagtctatgccacgtatttctgcttcaagtcagagccatgggct
acaaaacctcgggctcttttcagtagtggtgctatactgtacaaagcgtgctctataata
tttcctctcatctattcagaaatgaagtatctggttcactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (19)   
   Pfam (19)   
All databases (51)   

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