KEGG   Rattus norvegicus (rat): 292756
Entry
292756            CDS       T01003                                 
Symbol
Pak4
Name
(RefSeq) serine/threonine-protein kinase PAK 4
  KO
K05734  p21-activated kinase 4 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04660  T cell receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05170  Human immunodeficiency virus 1 infection
rno05206  MicroRNAs in cancer
rno05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    292756 (Pak4)
   04014 Ras signaling pathway
    292756 (Pak4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    292756 (Pak4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    292756 (Pak4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    292756 (Pak4)
  09158 Development and regeneration
   04360 Axon guidance
    292756 (Pak4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    292756 (Pak4)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    292756 (Pak4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    292756 (Pak4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    292756 (Pak4)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     292756 (Pak4)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: STE group
  STE20 family
   292756 (Pak4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal hnRNP_Q_AcD RIO1 Kdo KIND
Other DBs
NCBI-GeneID: 292756
NCBI-ProteinID: NP_001099708
RGD: 1307705
Ensembl: ENSRNOG00000019883
UniProt: F7FL63 B5DF62
Position
1:complement(92977437..93016721)
AA seq 593 aa
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRESPPPPARAHQENGMLEE
RAALARMAPDKAGGRGRATGHSEAGSGSGDRRRVGPEKRPKSSREGPGGPQEVSRDKRPL
SGPDVSTPQPGSLASETKLAAGRPFNTYPRADTDHPPRGTQGEPHTMAPNGPSAIGLAAP
QSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARALAAPAVPPAPGPPGPRSPQREPQR
VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQ
RRELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIA
AVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGT
PYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNL
HKASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRNR
NT seq 1782 nt   +upstreamnt  +downstreamnt
atgtttggaaagaagaagaagcgggtggagatctcggccccatccaacttcgagcaccgc
gtacacacaggcttcgatcagcatgagcagaagttcacagggctgccccgccagtggcag
agcctgattgaggagtcagcgcgcagacccaagcccctgatcgaccctgcttgcatcact
tccatccagcctggagcccccaagaccatcgtgcggggcagcaaaggtgccaaggatggg
gctctcacactgctgcttgacgaatttgagaacatgtcggtgacacgctccaactccctg
cgcagagagagtcctccaccccctgcccgcgcccatcaggaaaatggaatgctggaggag
cgggcagctctggccagaatggcccctgacaaagctggaggcaggggccgggccacaggc
cacagtgaggcaggcagtggcagtggtgacagacggcgggtggggccagagaagaggccc
aagtcatcaagggagggcccaggagggccccaggaggtctcccgtgataagcgccccctc
tctggtcctgatgtcagcactcctcagcctggcagtctggccagcgagacaaaactagca
gctggcagaccctttaacacataccctcgggctgacacggaccacccaccccggggtacc
cagggggagccacacaccatggcccctaatgggccatcagccataggcctggctgctcct
cagtcttcctcctcctcccggcctcccacccgagcccgtggtgctcccagcccgggagtg
ctgggtccccatgcctctgagccccagttggcccccccagcacgtgcccttgctgcccct
gctgtaccccctgctcctgggccccctgggcctcggtcaccacagcgggagccccaacga
gtatcccatgagcagttccgggccgccctgcagctagtggtggacccaggggaccctcgt
tcctatctagacaacttcatcaagattggcgagggctctacaggtattgtgtgcatagcc
actgtgcgaagctcgggcaaactggtggccgtcaagaagatggacttgcgtaagcagcag
agacgtgagctgctcttcaatgaggtggtgatcatgagggactaccggcatgaaaacgtg
gtggagatgtacaacagctacctggtaggcgatgagctctgggtggtcatggagttcctg
gagggaggcgccctcacggatattgtcacccacaccaggatgaatgaggaacagattgcc
gccgtgtgcctggctgtgcttcaggcgctgtctgtgctccatgcccagggcgtcatccac
cgtgacatcaagagtgactccatcctgctgacccacgatggccgggtgaagctgtccgac
ttcgggttttgtgcccaggtgagcaaggaggtgcctcggaggaagtcgctggtgggcacc
ccatactggatggccccagagctcatctcccgccttccctacgggccagaggtggatatc
tggtcactgggggtaatggtgatcgagatggtggatggggaacccccctacttcaacgag
ccacccctgaaagccatgaagatgattcgggacaacctgccgccccgactgaagaacctg
cacaaggcctcaccatctctgaaaggcttcttggatcgcctgctggtgcgtgacccagcc
cagcgggccactgctgctgagctgctgaagcacccgttcctcaccaaggcggggccgcca
gccagcattgtgccccttatgcgccagcaccgaaacagatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (38)   

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