KEGG   Rattus norvegicus (rat): 29392
Entry
29392             CDS       T01003                                 
Symbol
Bace1
Name
(RefSeq) beta-secretase 1 precursor
  KO
K04521  beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    29392 (Bace1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    29392 (Bace1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.46  memapsin 2
     29392 (Bace1)
Peptidases and inhibitors [BR:rno01002]
 Aspartic peptidases
  Family A1: pepsin family
   29392 (Bace1)
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N PE-PGRS_C
Other DBs
NCBI-GeneID: 29392
NCBI-ProteinID: NP_062077
RGD: 2191
Ensembl: ENSRNOG00000016847
UniProt: P56819 A6J452
Position
8:55038842..55061138
AA seq 501 aa
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKSVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHIPNIFSLQLCGAGFPLNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTADMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq 1506 nt   +upstreamnt  +downstreamnt
atggccccggcgctgcgctggctcctgctatgggtgggctcgggaatgctgcctgcccag
ggaacccatctcggtatccgactgccccttcgcagcggcctggcagggccacccctgggc
ctgaggctgccccgggagacggacgaggaacctgaggagcctggccggagaggcagcttt
gtggagatggtggacaacctgaggggaaagtccggccagggctactatgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagtagtaattttgca
gtgggggctgccccacaccctttcctgcatcgatactaccaaaggcagctgtccagtaca
taccgagacctccgaaagtctgtgtatgtgccctacacccagggcaagtgggagggggaa
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcctgacgactccttggagcccttttttgactcc
ctggtgaagcagacccacattccgaacatcttttccctgcagctctgtggcgctggcttc
cccctcaaccagactgaggcactggcctcggtgggagggagcatgatcattggtggtatc
gaccattccctatacactggcagtctctggtacacacccatccggcgggagtggtattat
gaagtgatcattgtacgtgtagaaatcaatggtcaagatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtatttgaagctgcagtcaagtccatcaaggcagcctcctcgacggagaagttcccggat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcacgaccccttggaacatt
ttcccagtcatttcactttacctcatgggtgaagtcaccaatcagtccttccgcatcacc
atccttcctcagcaatacctacggccagtggaagatgtggccacgtcccaagacgactgt
tacaagttcgccgtctcacagtcatccacaggcaccgttatgggagcggtcatcatggaa
ggcttctatgtggtctttgatcgagcccgaaagcgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacggcggcagtggaaggtccgtttgtcacggcagacatg
gaagactgtggctacaacattccacagacagatgagtcgacacttatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgctg
aaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (23)   

Download RDF
DBGET integrated database retrieval system