KEGG   Rattus norvegicus (rat): 29424
Entry
29424             CDS       T01003                                 
Symbol
Htt
Name
(RefSeq) huntingtin
  KO
K04533  huntingtin
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05016  Huntington disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    29424 (Htt)
   05022 Pathways of neurodegeneration - multiple diseases
    29424 (Htt)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    29424 (Htt)
   04131 Membrane trafficking [BR:rno04131]
    29424 (Htt)
   03029 Mitochondrial biogenesis [BR:rno03029]
    29424 (Htt)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     29424 (Htt)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    29424 (Htt)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    29424 (Htt)
SSDB
Motif
Pfam: Htt_C-HEAT Htt_N-HEAT Htt_bridge Htt_N-HEAT_1 HEAT
Other DBs
NCBI-GeneID: 29424
NCBI-ProteinID: NP_077333
RGD: 68337
Ensembl: ENSRNOG00000011073
UniProt: A6IK16 G3V9P7
Position
14:complement(80070456..80219668)
AA seq 3120 aa
MATLEKLMKAFESLKSFQQQQQQQQPPPQAPPPPPPPPPQPPQPPPQGQPPPPPPLPGPA
EEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSDDAES
DVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQK
CRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKS
SSPTVRRTAAGSAVSICQHSRRTQYFYNWLLNVLLGLLVPMEEDHPTLLILGVLLTLRCL
VPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQ
QLFRTPPPELLQALTTPGGLGQLTLVREEAGGRGRSGSIVELLAGGGSSCSPVLSRKQKG
KVLLGEEEALEDDSESRSDVSSSAFAASVKSEIGGELAASSSGVSTPGSVGHDIITEQPR
SQHTLQADSVDLSGCDLTSAATDGDEEDILSHSSSQFSAVPSDPAMDLNDGTQASSPISD
SSQTTTEGPDSAVTPSDSSEIVLDGADSQYLGVQIGQPQEEDEEEAAGVLSGEVSDVFRN
SSLALQQAHLLERMGHSRQPSDSSVDKFVSKDEVAEAGDPESKPCRIKGDIGQPNDDDSA
PLVHCVRLLSASFLLTGEKKALVPDRDVRVSVKALALSCIGAAVALHPESFFSKLYKVPL
STMESTEEQYVSDILNYIDHGDPQVRGATAILCGTLVYSILSRSRLRVGDWLGTIRALTG
NTFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCVLSLCSSSYSDLGLQLLIDMLPLKNS
SYWLVRTELLETLAEIDFRLVSFLEAKAESLHRGAHHYTGFLKLQERVLNNVVIYLLGDE
DPRVRHVAATTLTRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPPSHFSVST
ITRIYRGYSLLPSVTDVTMENNLSRVVAAVSHELITSTTRALTFGCCEALCVLSAAFPVC
TWSLGWHCGVPPLSASDESRKSCTVGMASMILTLLSSAWFPLDLSAHQDALILAGNLLAA
SAPKSLRSSWASEEEGSSAATRQEEIWPALGDRTLVPMVEQLFSHLLKVINICAHVLDDV
TPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQTSTPMSPKKGGEASTASRQSDTSGPV
TASKSSSLGSFYHLPSYLRLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILE
LATLQDIGKCVEEVLGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQFDGLSSNPSKSQ
CRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQADQEHDASGWFDVLQKVSA
QLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLLAQLVQLR
VNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPK
IIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLI
QYHQVLEMFILVLQQCHKENEDKWKRLSRQVADIILPMLAKQQMHIDSHEALGVLNTLFE
ILAPSSLRPVDMLLRSMFITPSTMASVSTVQLWISGILAILRVLISQSTEDIVLSRIQEL
SFSPYLISCPVINRLRDGDSNPTLGERSEGKQVKNLPEDTFSRFLLQLVGILLEDIVTKQ
LKVDMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAATRLFTSDGCEGSFYTLDSLN
ARVRAMVPTHPALVLLWCQILLLINHTDHRWWAEVQQTPKRHSLSCTKSLNPQISAEEDS
GSAAQLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLSHEPPVQDFI
SAIHRNSAASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQSGAVLTLYVDRLLGTP
FRALARMVDTLACRRVEMLLAANLQSSMAQLPEEELNRIQEHLQNTGLAQRHQRLYSLLD
RFRLSTVQDSLSPLPPVTSHPLDGDGHTSLETVNPDKDWYLQLVRSQCWTRSDSALLEGA
ELVNRIPAEDMSDFMMSSEFNLSLLAPCLSLGMSEIANGQKSPLFEAARRVTLDRVTNVV
QQLPAVHQVFQPFLPTEPTAYWSKLNDLFGDTTSYQSLTTLARALAQYLVVLSKVPAPLH
LPPEKEGHTVKFVVMTLEALSWHLIHEQIPLSLDLQAGLDCCCLALQVPGLWGVLSSPEY
VTHTCSLIHCVRFILEAIAVQPGDQLLGPESRSHTPRAVRKEEVDSDIQNLSHITSACEM
VADMVESLQSVLALGHKRNSTLPSFLTAVLKNIVVSLARLPLVNSYTRVPPLVWKLGWSP
KPGGDFGTVFPEIPVEFLQEKEVLKEFIYRINTLGWTSRTQFEETWATLLGVLVTQPLVM
EQEESPPEEDTERTQIHVLAVQAITSLVLSAMAVPVAGNPAVSCLEQQPRNKPLKALDTR
FGRKLSMIRGIVEQEIQEMVSQRENTATHHSHQAWDPVPSLLPATTGALISHDKLLLQIN
SEREPGNMSYKLGQVSIHSVWLGNNITPLREEEWDEEEEEEADAPAPTSPPVSPVNSRKH
RAGVDIHSCSQFLLELYSRWILPSSAARRTPVILISEVVRSLLVVSDLFTERTQFEMMYL
TLTELRRVHPSEDEILIQYLVPATCKAAAVLGMDKTVAEPVSRLLESTLRSTHLPSQIGA
LHGILYVLECDLLDDTVKQLIPVVSDYLLSNLKGIAHCVNIHSQQHVLVMCATAFYLMEN
YPLDVGPEFSASVIQMCGVMLSGSEESTPSIIYHCALRGLERLLLSEQLSRLDTESLVKL
SVDRVNVQSPHRAMAALGLMLTCMYTGKEKASPGRASDPSPATPDSESVIVAMERVSVLF
DRIRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQT
LHSAGQSSMVRDWVMLSLSNFTQRTPVAMAMWSLSCFLVSASTSPWVSAILPHVISRMGK
LEQVDVNLFCLVATDFYRHQIEEEFDRRAFQSVFEVVAAPGSPYHRLLACLQNVHKVTAC
NT seq 9363 nt   +upstreamnt  +downstreamnt
atggcaaccctggaaaaactgatgaaggctttcgagtcgctcaagtcgttccagcagcaa
cagcagcagcagcagccgccgccgcaggcgccgccaccaccgccgccgccgccgcctcaa
ccccctcagccgccgcctcaggggcagccgccgccaccaccgccgctgccaggtccggcc
gaggagccgctgcaccgaccaaagaaggaactctcagccaccaagaaggaccgtgtgaat
cactgtctaacaatatgtgaaaacattgtggcacagtctctcagaaattctccagaattt
cagaaactcttgggcattgctatggaactgtttctgctgtgcagcgacgatgcggagtca
gacgtcagaatggtggctgatgagtgcctcaacaaagtcatcaaagctttgatggactct
aatcttccaaggctacagttagaactctataaggaaattaaaaagaatggtgctcctcga
agtttgcgtgcagctctgtggaggtttgctgagctggctcacctggttcgacctcagaag
tgcaggccttatctggtgaatcttcttccatgtttgacccgaacaagcaaacgaccggag
gagtcagttcaggagactttggctgcagctgttcctaaaattatggcctcttttggcaat
ttcgcgaatgacaatgaaattaaggttctattgaaagctttcatagcaaatctgaagtca
agctctcccactgtgcggcggacagcagctgggtcagcagtgagtatctgccagcactct
aggaggacacagtacttctacaactggctcctgaatgtgctcctaggtttgctggttccc
atggaggaagaccaccccactctcctgatccttggtgtgttgctcacactgaggtgtcta
gtgcccttgctccagcagcaggtcaaggacacaagtctaaagggcagctttggggtaaca
cggaaagaaatggaagtctctccttctgcagagcagcttgtccaggtttatgaactgact
ttgcatcacacacagcaccaagaccataatgtggtgacaggggcattggagctcctgcag
cagctcttccgtacccctccacctgagctgctgcaagcactgaccacaccaggagggctc
gggcagctcactctggttcgagaggaagccgggggccgaggccgcagcgggagtatcgtg
gagcttttagctggagggggttcctcatgcagccctgttctctcaagaaagcaaaaaggc
aaagtgctcttaggagaggaagaagccttggaggatgactcggagtccaggtcagatgtc
agcagctcagcctttgcagcctctgtgaagagtgagattggtggagagctcgctgcttct
tcttcgggtgtctccactcccggttctgtaggtcacgacatcatcactgagcagcctcga
tcccagcacacacttcaagcagactctgtggatttgtcaggctgtgacttgaccagtgct
gctactgatggagatgaggaagacatcttgagccacagctccagccagttcagtgctgtt
ccatccgaccctgccatggacctgaatgatgggacccaggcctcctcacccatcagtgac
agttctcagaccaccactgaaggacctgattcagctgtgactccttctgacagttctgaa
attgtcttagatggtgctgacagccagtatttaggcgtgcagataggacagccacaggag
gaagacgaggaggaagctgcaggtgttctttctggtgaagtctcagacgttttcagaaac
tcttctctggcccttcagcaggcacacttgttggaaagaatgggtcatagccggcagcct
tctgacagcagtgttgataagtttgtttcaaaagatgaggttgctgaagctggggaccca
gaaagcaagccttgccgaatcaaaggtgacataggacagcctaatgatgatgattctgct
cctctggtacattgtgtccgtcttttatccgcttcctttttgttaactggcgaaaagaaa
gcactggttccagacagagatgtgagagtcagtgtgaaggccctggccctcagctgtatt
ggtgcagctgtggcccttcatccagagtcgttcttcagcaaactctacaaagtacctctc
agtaccatggaaagtactgaggaacagtatgtctctgacatcctgaactacatcgatcat
ggagaccctcaggtgcgaggagctactgccattctctgtgggacccttgtctactccatc
ctcagcaggtcccgtctccgtgttggtgactggctgggcaccatcagggccctgacagga
aatacattttctctggtggactgcattcctttactgcagaaaactttgaaggatgaatct
tctgttacttgcaagttggcttgtacagctgtgaggcactgtgtcctgagtctttgcagc
agcagctacagtgacttgggattacaactgcttattgacatgctgcctctgaagaacagc
tcctactggctggtgaggactgaactgctggaaactcttgcagagattgatttcaggctg
gtgagttttttggaggcaaaagcagaaagtttacaccgaggggctcatcattatacaggg
tttctaaaactacaagaacgagtactcaataatgtggtcatttatttgcttggagatgaa
gaccccagggttcgacatgttgctgcgacgacattgacaagacttgtcccaaagctgttt
tataagtgtgaccaaggacaggctgacccagtcgtggctgtagcaagagatcaaagtagt
gtttacctgaagctcctcatgcatgagacccagccaccatcccacttctccgtcagcacc
ataaccagaatctatagaggctacagcttactaccaagtgtaacagatgtcaccatggaa
aacaacctctcaagagtcgttgccgcagtttctcatgaactcattacgtcaactacacgg
gcactcacatttgggtgctgtgaagccttgtgtgttctttcagccgcctttccagtttgc
acttggagtctaggatggcactgtggagtgcccccactgagtgcctctgatgagtccagg
aagagctgcactgttgggatggcctccatgattctcaccttgctttcatcagcttggttc
ccactggatctctcagcccatcaggatgccttgattttggctggaaacttgctagcagcg
agtgcccccaagtctctgagaagctcatgggcctcggaagaagaaggcagctcagcagcc
accagacaggaggagatctggcctgccctgggggatcggactctggtgcccatggtggag
cagcttttctcccacctgctgaaggtgatcaatatctgtgctcatgtcttggatgacgtg
actcctggaccagcaatcaaggcagctttgccttctctcacaaaccccccttctctaagt
cctattcgacggaaagggaaggagaaagagcccggagaacaaacatccactccgatgagt
cccaagaaaggtggagaggccagtacagcctctcgacagtcagacacctcaggacctgtc
acagcgagtaaatcatcttcacttgggagtttctaccatctcccttcctacctcagactg
catgatgtcctgaaagccactcacgccaactataaggtcaccttagatcttcagaacagc
actgaaaagtttggggggttcctgcgctctgccttggacgtcctttctcagattctagag
ctggcgacactgcaggacattggaaagtgtgttgaagaggtccttggatacttgaaatcc
tgctttagtcgagaaccaatgatggcgactgtctgtgttcagcagctattgaagactctc
tttgggacaaacttagcctcacagtttgatggcttatcttccaaccccagcaagtctcag
tgccgagcacagcgccttggctcttccagtgtgaggcccggcttatatcactactgcttc
atggcaccatacacgcacttcacgcaggctttggctgatgccagcctgaggaacatggta
caggcggaccaggagcacgatgcctcagggtggtttgatgtactccagaaagtgtctgct
cagttgaagacgaaccttacaagtgtcacaaagaaccgtgcagataagaacgctattcat
aaccacattaggttatttgagcctcttgttataaaagcattgaagcagtacaccacgaca
acatcagtacaactgcagaagcaggttttggatttgctggcacagctggttcagctacgg
gtcaattactgtctactggattcagatcaggtgttcatcgggtttgtgctgaagcagttt
gagtacattgaagtgggccagttcagggaatcagaggcaattattccaaatatatttttc
ttcctggtactattatcttatgagcgctaccattcaaaacagatcattggaattcctaaa
atcatccagctgtgtgatggcatcatggccagtggaaggaaggctgtcacacatgctatt
cctgcgctgcagcccattgtccatgacctctttgtgttaagaggaacaaataaagctgat
gcagggaaagagcttgaaacccagaaggaggtggtggtctcaatgctgttacgactcatc
cagtaccatcaggtgctagagatgttcatcctcgtcctgcagcagtgccacaaagagaat
gaggacaagtggaaacggctctctcggcaggtcgcagacatcatcctgcccatgttagcc
aagcagcagatgcatattgactctcatgaagcccttggagtattaaataccttgtttgag
attttggctccttcctccctacgtcctgtggacatgcttttgcggagtatgttcatcact
ccaagcacaatggcatctgtaagcactgtgcagctgtggatatctggaatcctagccatt
ctgagggttctcatttcccagtcaaccgaagacattgttctttctcgtattcaggagctc
tccttctctccatatttaatttcctgtccagtaattaacaggttaagggatggagacagt
aatccaacactaggagaacgcagtgaagggaaacaagtaaagaatttgccagaagataca
ttctcaaggtttctcttacagctggttggtattcttctggaagacattgttacaaaacag
ctcaaagtggacatgagtgaacagcagcatacattctattgccaagagctcggcacactg
ctcatgtgtctgatccacatattcaaatctggaatgttccggagaatcacagccgctgcc
actagactcttcaccagtgatggctgtgaaggcagcttctatactctagatagcctgaat
gcacgggtgcgagccatggtgcccacacacccagctctggtactgctctggtgtcagatc
ctactgctcatcaaccacactgaccaccgatggtgggccgaggtgcagcagacgcccaag
agacacagtctgtcctgcacgaagtcactaaacccccagatatctgctgaagaggattct
ggctcagcagctcagcttggaatgtgcaatagagaaatagtacgaagaggggcccttatt
ctcttctgtgattatgtctgtcagaatctccatgactcagaacacttaacatggctcatt
gtgaatcacattcaagatctgatcagcttgtcccacgagcctccagttcaagactttatt
agtgccattcatcgtaattctgcagctagtggtctttttatccaggcaattcagtctcgc
tgtgaaaatctttcaactccaaccactctgaagaaaacacttcagtgcttggaaggcatc
catctcagccagtctggtgctgtgctcacactgtatgtggacaggctactgggcacccct
ttccgtgcgctggctcgcatggtcgacaccctggcctgtcgccgagtagaaatgcttttg
gctgcaaatttacagagcagcatggcccagttgccagaggaggaactgaacagaatccag
gaacacctccagaacactgggcttgcacaaagacaccaaaggctctattcactgctggac
agattccgactctctactgtgcaggactcacttagccccttgcccccagtcacttcccac
cctctggatggggatgggcacacatccctggaaacagtgaatccggacaaagactggtac
ctccagcttgtcagatcccagtgttggaccaggtcagattctgcactgctggaaggtgca
gagctggtgaaccgtatccctgctgaagatatgagtgacttcatgatgagctcggagttc
aacctaagccttttggctccctgcttaagccttggcatgagcgagattgctaatggccaa
aagagtcccctttttgaagcggctcgtagggtgactctggaccgggtgaccaatgtggtt
cagcagctgcctgcagtccatcaagtcttccagcctttcctgcctacagaacccacagcc
tactggagcaagctgaatgatctctttggtgataccacatcataccagtctctgaccaca
cttgcccgtgccctggcacagtacctggtggtgctctccaaagtgcctgctcctttgcac
cttcctcctgagaaggaggggcacacggtgaagtttgtggtaatgacacttgaggccctg
tcatggcatttgatccatgagcagatcccactgagtctggacctccaagccggcctagac
tgctgctgcctggcactgcaggtgcctggcctctggggggtgctgtcctccccagagtac
gtgactcatacttgctcccttatccactgtgtgcgattcatcctggaagccattgcagta
caacctggagaccaacttcttggtccggaaagcaggtcacatactccaagggctgtcaga
aaggaggaagtagactcagatatacaaaacctcagtcacatcacttcggcctgcgagatg
gtggcagacatggtggaatccctgcagtcggtgctggccctgggccacaagaggaacagc
accctaccttcatttctcacagctgtgctgaagaacattgttgtcagtctggcccgcctc
cccctcgttaacagctatactcgtgtgcctcctctggtatggaaactcgggtggtcaccc
aagcctggaggggatttcggcacagtgtttcctgagatccctgtagagttcctccaggag
aaggaggtcctcaaggagttcatctaccgcatcaacaccctagggtggaccagtcgtact
caattcgaagaaacttgggccaccctccttggtgtcctggtgactcagcccttggtgatg
gaacaggaagagagcccaccagaggaagacaccgaaaggacccagatccacgtcctggct
gtacaggccatcacctctctagtgctcagcgcaatggctgtgcctgtggctggcaatcca
gctgtaagctgcttggagcaacagccccggaacaagccactgaaggctctcgataccaga
tttggaagaaagttgagcatgatcagagggattgtagaacaagaaatccaagagatggtt
tcccaaagagagaatactgccactcatcattctcaccaggcatgggatcctgtcccttct
ctgttaccagctactacaggtgctcttatcagccatgacaagctgctgctgcagatcaac
tcagagcgggagccaggcaacatgagctacaagctgggccaggtgtccatacactccgtg
tggctggggaacaacatcacacccctgagagaggaggaatgggatgaggaggaggaggaa
gaagcggatgcccctgcgccaacatcaccacctgtgtctccagtcaattccagaaaacac
cgtgctggggttgatattcactcctgttcgcagtttctgcttgaattatacagccgttgg
atcctgccatccagtgcagccagaaggacccctgtcatcctgatcagtgaagtggttcga
tctcttcttgtggtgtcagacttattcactgaacgtacccagtttgaaatgatgtatctg
acgctgacagaactacggagagtgcacccttcagaagatgagatcctcattcaatacctg
gtgcctgccacctgtaaggcagctgctgttcttggaatggacaaaactgtggcagagccg
gtcagccgcctactggagagcacactcaggagcacccacctgcccagccagatcggagcc
ctgcatggcatcctctatgtgttggagtgtgacctcttggatgacactgtaaagcagctc
attccagttgttagtgactatctgctgtccaacctcaaaggaatagcccactgcgtgaac
attcacagccagcagcatgtgctggtgatgtgtgccactgcattctacctgatggaaaac
taccctctggatgtggggccagaattctcagcatctgtgatacagatgtgtggagtaatg
ctgtctggaagtgaggagtccaccccctccatcatttaccactgtgccctccggggtctg
gaacggctcctgctgtctgagcagctctctcggctagacacggagtccttggtcaagcta
agtgtggacagagtgaatgtacaaagcccacacagggccatggcagccctaggcctgatg
cttacctgcatgtacacaggaaaggaaaaagccagtccaggcagagcttctgaccccagc
cctgctacccctgacagcgagtctgtgattgtagctatggagcgagtgtctgtgctcttt
gacaggatccgcaagggatttccctgtgaagccagggtcgtggcaaggatcctgcctcag
tttctagatgacttctttccacctcaagatgtcatgaacaaagtcattggagagttcctg
tccaaccagcagccatacccacagttcatggccactgtagtatacaaggtttttcagact
ctgcacagtgctgggcagtcatccatggtccgggactgggttatgctgtctctgtccaac
ttcacacaaagaactccagttgccatggccatgtggagcctctcctgcttccttgtcagt
gcatctaccagcccatgggtttctgcaatccttccacacgtcatcagcaggatgggcaaa
ctggagcaggtggatgtgaaccttttctgcctggttgccacagacttctacagacaccag
atagaggaggaattcgaccgcagggctttccagtctgtgtttgaggtggtggcagcacca
ggaagtccataccacaggctgcttgcttgtttgcaaaatgttcacaaggtcaccgcctgc
tga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (9)   
   UniProt (2)   
   RefSeq(pep) (7)   
DNA sequence (13)   
   RefSeq(nuc) (7)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

Download RDF
DBGET integrated database retrieval system