KEGG   Rattus norvegicus (rat): 29433
Entry
29433             CDS       T01003                                 
Symbol
Pak3
Name
(RefSeq) serine/threonine-protein kinase PAK 3
  KO
K05733  p21-activated kinase 3 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04660  T cell receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05132  Salmonella infection
rno05170  Human immunodeficiency virus 1 infection
rno05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    29433 (Pak3)
   04014 Ras signaling pathway
    29433 (Pak3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    29433 (Pak3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    29433 (Pak3)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    29433 (Pak3)
  09158 Development and regeneration
   04360 Axon guidance
    29433 (Pak3)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    29433 (Pak3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    29433 (Pak3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    29433 (Pak3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    29433 (Pak3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     29433 (Pak3)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: STE group
  STE20 family
   29433 (Pak3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo
Other DBs
NCBI-GeneID: 29433
NCBI-ProteinID: NP_062083
RGD: 3251
Ensembl: ENSRNOG00000004676
UniProt: Q62829 A6KG82
Position
X:111912967..112171037
AA seq 544 aa
MSDSLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL
DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEE
EEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEATPPSAENANSSTLYRNTDRQ
RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN
LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD
EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS
TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP
ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAIK
NSSR
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtctgacagcttggataacgaagaaaaacctccagctcccccactgaggatgaacagt
aacaaccgagattcttcagcactcaaccacagctccaaaccactgcccatggccccggaa
gagaagaataagaaagccaggcttcgctctatcttcccaggaggaggggataaaaccaat
aagaagaaagagaaagaacgcccagagatctctcttccttcagactttgagcatacgatt
catgtgggttttgatgcagtcaccggggaattcactggaattcctgaacaatgggctcga
ctgctccaaacctccaacattacaaaactggaacagaagaagaacccacaggctgttctg
gatgttctcaagttttacgactccaaagaaacagtcaacaaccagaaatacatgagcttt
acatcaggagataaaagtgcccatggatatatagcagcacatcagtcgaataccaaaaca
gcttcagaacctcctttggctcctcctgtatctgaagaagaggatgaagaagaggaagag
gaagaagatgataatgagcccccgcctgtcattgcaccaagaccagagcatacaaaatca
atctatactcgttctgtggttgagtcaattgcttcaccagcagcaccaaataaagaagcc
accccaccttctgctgagaatgccaattccagtactttgtacaggaatacagatcggcaa
agaaaaaaatccaagatgacagatgaggagatcctagagaagctaagaagcattgtgagt
gttggggacccaaagaagaaatatacaagatttgaaaaaattggccaaggggcatcagga
actgtttacacagcactagacattgcgacaggacaagaggtggctataaagcaaatgaac
cttcaacagcagcccaaaaaggaattaattattaatgaaattcttgtcatgagggaaaat
aagaaccccaatattgtcaattatttagatagctacttagtgggtgatgaactgtgggta
gtcatggaatacttggctggtggctctttgactgacgtggtcacagaaacctgtatggat
gaaggacagatagcagccgtctgtagagagtgcctccaagctttggatttcttgcactca
aaccaagtgatccacagagatataaagagtgacaatattctcctcgggatggatggttct
gttaaactgactgattttggattctgtgcccaaatcactcctgagcaaagtaaacgaagc
actatggtgggaactccctattggatggcacctgaggtggtaactcgaaaagcttatggc
ccgaaagttgatatctggtctctgggaatcatggccattgaaatggtggaaggtgaaccc
ccttaccttaatgaaaatccactcagggccttatatctgatagccactaatggaacccca
gagctccagaatcccgagagactgtcagctgtattccgtgacttcttaaatcgctgtctt
gagatggatgtggatagacgagggtctgccaaggagcttttgcagcatccatttttaaaa
ttagccaagcccctgtccagcctcactcctctgattcttgctgcaaaggaagccattaag
aacagtagccgttag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (20)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (21)   
   RefSeq(nuc) (17)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (70)   

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