KEGG   Rattus norvegicus (rat): 294515
Entry
294515            CDS       T01003                                 
Symbol
Foxo3
Name
(RefSeq) forkhead box protein O3
  KO
K09408  forkhead box protein O3
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04062  Chemokine signaling pathway
rno04068  FoxO signaling pathway
rno04137  Mitophagy - animal
rno04151  PI3K-Akt signaling pathway
rno04152  AMPK signaling pathway
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04218  Cellular senescence
rno04722  Neurotrophin signaling pathway
rno04917  Prolactin signaling pathway
rno04936  Alcoholic liver disease
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05213  Endometrial cancer
rno05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    294515 (Foxo3)
   04151 PI3K-Akt signaling pathway
    294515 (Foxo3)
   04152 AMPK signaling pathway
    294515 (Foxo3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    294515 (Foxo3)
  09143 Cell growth and death
   04218 Cellular senescence
    294515 (Foxo3)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    294515 (Foxo3)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    294515 (Foxo3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    294515 (Foxo3)
  09149 Aging
   04211 Longevity regulating pathway
    294515 (Foxo3)
   04213 Longevity regulating pathway - multiple species
    294515 (Foxo3)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    294515 (Foxo3)
  09162 Cancer: specific types
   05213 Endometrial cancer
    294515 (Foxo3)
   05223 Non-small cell lung cancer
    294515 (Foxo3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    294515 (Foxo3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    294515 (Foxo3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    294515 (Foxo3)
Transcription factors [BR:rno03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    294515 (Foxo3)
SSDB
Motif
Pfam: FOXO_KIX_bdg Forkhead FOXO-TAD Pal1
Other DBs
NCBI-GeneID: 294515
NCBI-ProteinID: NP_001099865
RGD: 1309196
Ensembl: ENSRNOG00000000299
Vega: OTTRNOG00000001101
UniProt: A6K6Z2 D3ZBQ1
Position
20:complement(47251968..47348254)
AA seq 672 aa
MAEAPASPVPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
DDDEDDEDSGGRGSSAMVIGGGVSSALGSGLLLEDSARLLSPGGQDLGTGPASSAGALSG
GTQTQLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLS
QIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGG
KSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAAPESADDSPSQLSKWPGSPTSRSSD
ELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKP
CTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQASPPGGLMQRSSSFPYTAKSS
GLGSPTSSFNSTVFGPASLNSLRQSPMQTIQENRPATFSSVSHYGNQTLQDLLTSDSLSH
SDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQ
GALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSASANLPV
MGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTG
AKQASSQSWVPG
NT seq 2019 nt   +upstreamnt  +downstreamnt
atggcagaggcaccagcctccccggtcccgctctctccgctcgaagtggagctggaccca
gagttcgagccacagagtcggccacgctcctgtacgtggcccctgcagaggccggagctg
caggcgagcccggccaagccctcgggggagacggcggcagactccatgatccccgaggag
gacgacgatgaagacgacgaggacagcggcggccgaggcagctcggccatggtgatcggt
ggcggcgtgagcagtgcgctgggctccgggctgctcctcgaagattcggccaggctgctg
tctcccggagggcaggacctcgggacggggccagcgtcctccgcaggcgcgctgagtggg
ggcacgcagacgcagctgcagcctcagcagccactgccaccgccgcagccgggggcggct
gggggctctgggcaaccgaggaaatgctcctcgcggcggaatgcctgggggaacctgtcc
tacgctgacctgatcacccgcgccatcgagagctccccggacaaacggctcactttgtcc
cagatctacgagtggatggtgcgctgtgtgccctacttcaaggataagggcgacagcaac
agctctgcgggctggaagaactccatccgccacaacctgtcactgcacagccgtttcatg
cgggttcagaacgaagggactggcaagagctcttggtggatcatcaaccccgatggggga
aagagtgggaaggctccccggcggcgggccgtctccatggacaacagcaacaagtacacc
aagagccgaggccgggcagccaagaagaaggcggccctgcaggctgccccagagtcggca
gacgacagcccttcccaactctccaagtggccgggcagccccacatcccgcagcagcgac
gagctggacgcctggaccgacttccgctcgcgcaccaattccaacgccagcaccgtgagc
ggccgcctgtcacccatcttggcgagcacggagctggatgacgtccaggacgatgacggg
cccctctcccccatgctctacagcagctctgccagcctgtcgccttccgtaagcaagccg
tgtaccgtggagctgccgcggctgactgacatggcgggcaccatgaatctgaacgatggg
ctggccgagaacctcatggatgacctgctagataacatcgcgctcccgccctcccaggcg
tcgcctcctggcgggcttatgcagcggagctccagcttcccgtacaccgccaagagctcc
ggcctgggctccccaaccagctcctttaacagtaccgtgttcggacctgcgtcactcaac
tccctgcgccagtcgcccatgcagaccatccaggagaacagaccagccaccttttcttcc
gtgtcgcactacggcaaccagacactccaagacctgctcacttcggactcgctcagccac
agcgatgtcatgatgacccagtcagaccccttgatgtctcaggctagcaccgctgtgtcc
gcccagaacgcccgccggaacgtgatgcttcgcaacgacccaatgatgtcctttgccgcc
cagcctacccaggggagtttggtcaatcagaacttgctccaccaccagcaccaaacccag
ggcgctcttggtggcagccgtgccttgtcaaattctgtcagcaacatgggcttgagtgac
tccagcagcctcggctcagccaaacaccagcagcagtctcccgtcagccagtctatgcaa
accctctcggactctctctcaggctcctcactgtattcagccagtgcaaaccttcccgtc
atgggtcacgacaagttccccagtgacttggacctggacatgttcaatgggagcttggag
tgtgacatggagtccatcatccgtagcgaactcatggatgccgatgggttggattttaac
tttgactccctcatctccacacagaacgttgttggtttgaacgtggggaacttcactggt
gctaagcaggcctcatctcaaagctgggtgccaggctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (15)   
   KEGG PATHWAY (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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