KEGG   Rattus norvegicus (rat): 295378
Entry
295378            CDS       T01003                                 
Symbol
Vav3
Name
(RefSeq) guanine nucleotide exchange factor VAV3
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04024  cAMP signaling pathway
rno04062  Chemokine signaling pathway
rno04510  Focal adhesion
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05135  Yersinia infection
rno05205  Proteoglycans in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    295378 (Vav3)
   04024 cAMP signaling pathway
    295378 (Vav3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    295378 (Vav3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    295378 (Vav3)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    295378 (Vav3)
   04660 T cell receptor signaling pathway
    295378 (Vav3)
   04662 B cell receptor signaling pathway
    295378 (Vav3)
   04664 Fc epsilon RI signaling pathway
    295378 (Vav3)
   04666 Fc gamma R-mediated phagocytosis
    295378 (Vav3)
   04670 Leukocyte transendothelial migration
    295378 (Vav3)
   04062 Chemokine signaling pathway
    295378 (Vav3)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    295378 (Vav3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    295378 (Vav3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    295378 (Vav3)
SSDB
Motif
Pfam: RhoGEF SH3_2 CAMSAP_CH CH SH2 SH3_1 SH3_9 C1_1 PH CDC24 Filamin LZ3wCH PH_10 C1_2 Prok-RING_1 zf-RING_16
Other DBs
NCBI-GeneID: 295378
NCBI-ProteinID: NP_001178643
RGD: 1565941
Ensembl: ENSRNOG00000020485
UniProt: A0A8I5ZPB5
Position
2:199699861..200042344
AA seq 847 aa
MEPWKQCAQWLIHCKVLPANHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEI
NLRPQMSQFLCLKNIRTFLAACCDTFGMKKSELFEAFDLFDVRDFGKVIETLSRLSRTPI
ALATGIRPFPTEESVNDEDIYKGLPDLIDETRVEDEEDLYDCVYGEDEGGEVYEDLMKAE
EAHQAKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPD
LVKVHRSLMQEIHDSIVNKDDHNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKE
DVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKSNLKLALDA
MKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQER
HIFLFDLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGL
EFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQ
GYLCFKCGAKAHKECLGRVDNCGRVNSVEQGPFKPPEKRTNGLRRASRQVDPGLPKMRVI
RNYTGTPPPALHEGPPLHIQAGDTVELLRGEAHTVFWQGRNLASGEVGFFPSDAVKPSPC
VPKPVDYSCQPWYAGPMERLQAETELINRVNSTYLVRLRTKESGEYAISIKYNNEAKHIK
ILTRDGFFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHASGQRGNRT
GNSLLSPKVLGIAIARYDFCARDMRELSLLKGDMVKIYTKMSANGWWRGEVNGRVGWFPS
TYVEEDE
NT seq 2544 nt   +upstreamnt  +downstreamnt
atggagccgtggaagcagtgcgctcagtggctcatccactgcaaagtgctgcccgccaac
caccgggtgacctgggactcggcgcaggtgttcgacctggcgcagaccctccgcgatgga
gtcctgctctgccagctgctcaacaacctgcggccacactccatcaatctgaaggagatc
aacctgagaccccagatgtcccagtttctctgtctgaagaatatccggacatttctggcc
gcctgctgtgacacgttcggaatgaagaaaagtgagctttttgaggcatttgacctattc
gatgttcgtgactttggaaaggttatagaaacattatctcgcctatcccgaacaccaata
gcattggccacaggaatcaggccattccccacggaagaaagtgtaaatgatgaagacatc
tacaaaggccttcctgacctgatagatgaaacccgtgtggaggacgaagaagacctctat
gactgtgtgtacggggaggatgaaggcggagaagtctatgaagatttgatgaaggcggag
gaggctcaccaagctaaatcacaagaaaatgatatacggagttgttgcctagcagaaatt
aggcagacagaagaaaaatacacagaaactttggagtcaatagaaaaatatttcatggca
ccattgaaaagatttctgacagcggcggaatttgattcagtatttatcaacattcctgac
cttgtaaaagttcatcggagcttaatgcaagagattcacgattccattgtaaataaagat
gaccataacttgtatcaagtttttattaactacaaggaaagattggttatttatggacag
tactgcagtggagtggagtcagccatctctagcctagactacatctctaagacaaaagaa
gatgtcagactgaaactagaggaatgttcaaagagagccaataatgggaaatttactctg
cgtgatttgctggtagttcccatgcagcgggtgctgaaatatcacctcctccttcaggag
ctggttaaacacacccatgatcccatggagaagtcgaacctgaagctggctctggatgca
atgaaggacttggcacaatatgtgaatgaagtaaaaagagataatgagacccttcgtgaa
attaagcagtttcagctatctatagaaaatttgaaccagcccgttttgctctttgggcga
ccgcagggagacggtgaaatccgaataaccacactggacaagcatacgaaacaagaaagg
catatcttcttattcgatctggcagtgattgtctgtaaaaggaaaggggataactacgag
atgaaggaaataatagatctccagcagtacaagatcgccaacaaccctaccacggataaa
gagaataaaaagtggtcttatggcttctacctcatccatacccaaggacaaaatgggctg
gaattttattgcaaaacaaaagatttaaagaaaaaatggctggaacagtttgaaatggct
ttatccaacataaggccggactatgcagactccaatttccatgacttcaagatgcacaca
ttcactcgggtgacatcctgtagggtctgccaaatgctcctgagggggacattttatcaa
ggctacttatgttttaagtgtggagcaaaagcgcataaagaatgtttgggaagagtagac
aattgtggcagagttaattccgttgaacaagggccattcaaaccaccggagaagcggacc
aatggacttcggagagcttccagacaggtggatccaggcttgccgaagatgcgggtcatt
aggaactacactggcaccccgcccccagctcttcacgaaggaccaccgttgcatatccag
gcaggggacactgttgaacttctgagaggagaggcacacactgttttctggcagggacga
aacttagcttcaggagaggttggatttttcccaagcgatgctgtcaagccatctccatgt
gtacctaaaccagtagattattcttgccaaccctggtatgctggcccaatggaaagattg
caggcagaaactgaacttattaacagggtgaatagcacttaccttgtaaggctcaggacc
aaagagtctggagaatatgcaattagcattaagtacaataatgaagcaaaacacatcaag
attttaacaagagatggcttttttcacattgcagaaaatagaaaatttaaaagcttaatg
gaacttgtggagtactacaagcaccattctcttaaagaagggttcaggaccttagatacg
acgctacagtttccatacaaggagcctgaacacgcatctggacagaggggtaatagaaca
ggcaacagcttgctaagtcccaaagttctgggcattgccatcgctcggtatgacttctgt
gcaagagatatgcgggagctctccctattgaaaggagacatggtgaagatttacacaaag
atgagtgcaaatggctggtggagaggagaagtaaatggcagggtgggctggtttccatcc
acgtatgtggaagaagacgagtaa

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (16)   
   Pfam (16)   
All databases (45)   

Download RDF
DBGET integrated database retrieval system