KEGG   Rattus norvegicus (rat): 296603
Entry
296603            CDS       T01003                                 
Symbol
Vav2
Name
(RefSeq) guanine nucleotide exchange factor VAV2
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04024  cAMP signaling pathway
rno04062  Chemokine signaling pathway
rno04510  Focal adhesion
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05135  Yersinia infection
rno05205  Proteoglycans in cancer
rno05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    296603 (Vav2)
   04024 cAMP signaling pathway
    296603 (Vav2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    296603 (Vav2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    296603 (Vav2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    296603 (Vav2)
   04660 T cell receptor signaling pathway
    296603 (Vav2)
   04662 B cell receptor signaling pathway
    296603 (Vav2)
   04664 Fc epsilon RI signaling pathway
    296603 (Vav2)
   04666 Fc gamma R-mediated phagocytosis
    296603 (Vav2)
   04670 Leukocyte transendothelial migration
    296603 (Vav2)
   04062 Chemokine signaling pathway
    296603 (Vav2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    296603 (Vav2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    296603 (Vav2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    296603 (Vav2)
SSDB
Motif
Pfam: RhoGEF SH3_2 CAMSAP_CH CH SH3_1 SH3_9 SH2 PH C1_1 SH2_2 CDC24 C1_2 PH_10 zf-RING_16 zf-RING-like
Other DBs
NCBI-GeneID: 296603
NCBI-ProteinID: NP_001100033
RGD: 1306285
Ensembl: ENSRNOG00000007422
UniProt: D3ZYG0
Position
3:complement(30982754..31152116)
AA seq 868 aa
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI
AQSKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMKMGLTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRQVLSPVDMATIFINLE
DLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLLIYGEYCSHMEHAQSALNQLLASRD
DFRQKVEECTLKVQEGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQCSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRKGYSYELKEVIELLFHKMTDDPMHNKDIKKWSYGFYLIHLQGKQGF
QFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQ
GYLCTRCGVGAHKECLEVIPPCKMSSPADADAPGAGLGPKMVAVQNYHGNPAPPGKPVLT
FQTGDVIELLRGDPDSPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPVGRPPSREIDYTA
YPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDSWIH
ITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKFPYKSRERAATRASSRSPASCASYSF
SFLSPQGLSFAPQGPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIG
GDQGWWKGETNGRIGWFPSTYVEEEGIQ
NT seq 2607 nt   +upstreamnt  +downstreamnt
atggagcagtggcggcaatgcggccgctggctcattgactgcaaggtcctgccgcccaac
caccgcgtcgtgtggccctcggcggtggtcttcgacctggcgcaggcgctgcgcgacggc
gtccttctgtgccagctgctgcacaacctctcccccggctccatcgaccttaaggacatc
aacttccggccgcagatgtcccagttcctgtgtctgaagaatattcgcaccttcctcaaa
gtctgccacgacaaatttggactaaggaacagtgagctgtttgaccctttcgacctcttt
gatgtccgagacttcgggaaggtcatctctgccgtgtcccgtctgtccctgcacagcatc
gcgcagagcaaagggatcaggccttttccatcagaggagacggctgaaaacgatgacgat
gtctaccggagtctggaagagctggctgacgagcatgacctgggtgaggacatctacgac
tgtgtcccgtgtgaagatgaaggagatgacatttatgaggacatcatcaaggtggaggtg
cagcagcccatgaaaatgggactaaccgaggacgacaagaggagctgctgcttgttagag
attcaggagaccgaggccaagtactaccgcaccctggaggacattgagaagaactacatg
ggtcccttgcggcaggtgctgagccccgtggacatggccaccatcttcatcaacctggag
gacctcatcaaggtgcaccacagctttctgcgagccatcgatgtgtccatgatggctggt
ggcagtaccctggctaaggtcttcctggagtttaaggaacggctcctgatctacggagag
tactgtagccacatggagcatgcgcagagcgcactgaaccagctcctcgccagccgagac
gacttcaggcagaaagtggaggagtgcacactcaaggtccaggagggcaagttcaagctg
caggatctgctggtggtgcccatgcagcgggtgctcaagtaccacctgttgctcaaggag
ctcctgagccattccgcagaccggcctgaaagacaacagctcaaagaagcactggaagcc
atgcaggacttggccatgtatattaatgaagtgaaacgggacaaggagaccttgaagaag
attagtgagttccagtgctccatagaaaacctgcaagtgaagctggaggaatttgggagg
ccgaagattgacggggagctgaaagttcggtccatagtcaaccacaccaagcaagacagg
tacctgttcctgtttgacaaggtggtcatcgtgtgtaagaggaagggctacagctatgag
ctgaaggaggttattgaactgctcttccacaagatgactgatgaccccatgcacaacaaa
gacatcaagaagtggtcctatggcttctacctgattcacctccaagggaagcaaggcttt
cagttcttctgcaagacggaagacatgaaacggaagtggatggagcagttcgagatggcc
atgtcaaacatcaagccagacaaggccaatgccaaccatcatagtttccagatgtacacg
tttgacaagaccaccaactgcaaagcctgcaagatgttcctcaggggtaccttctaccag
ggatacctgtgtaccagatgtggtgtcggggcacacaaggagtgcctggaggtgataccc
ccctgcaagatgagttcgcctgcagatgcggacgctcccggagcaggactaggtcccaag
atggttgccgtgcagaattaccatggtaacccagcccctcccgggaagcccgtgttgacc
ttccagacaggggatgtgatagagctgctccggggtgaccccgattctccttggtgggag
gggaggctggttcaaactcggaagtcagggtatttccccagctcatctgtgaagccctgc
ccggtggacggaaggccgcctgttggccgcccgccatcccgggagatcgattacactgca
tacccgtggttcgctggcaacatggaacggcagcagacggacaatctactcaagtctcat
gccagcgggacctacctcatcagagagcgcccagcagaggcagagcgtttcgccatcagc
atcaagttcaatgatgaagtgaaacacatcaaggtggtggaaaaagacagctggatccac
atcacggaagctaagaagtttgagagcctcctggagctggtggagtactaccagtgccac
tcacttaaggagagcttcaagcagttagacactacactcaagttcccctacaagtctcgg
gagcgcgccgccaccagggcctcaagccgatctccagcttcgtgtgcttcctacagcttt
tcttttctcagtcctcagggcctcagctttgccccccagggcccctctgctcccttctgg
tcagtgttcacaccgcgggtcatcggcacagccgtggccaggtacaactttgctgcacga
gacatgcgggagctgtcgctgcgggaaggtgatgtggtgaagatctacagccggatcggt
ggggaccagggctggtggaagggcgagacgaacgggcggatcggttggtttccttcgacg
tacgtggaagaggaaggcatccagtga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (15)   
   Pfam (15)   
All databases (49)   

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