KEGG   Rattus norvegicus (rat): 29693
Entry
29693             CDS       T01003                                 
Symbol
Atp2a2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform b
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04148  Efferocytosis
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04380  Osteoclast differentiation
rno04919  Thyroid hormone signaling pathway
rno04972  Pancreatic secretion
rno05010  Alzheimer disease
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    29693 (Atp2a2)
   04024 cAMP signaling pathway
    29693 (Atp2a2)
   04022 cGMP-PKG signaling pathway
    29693 (Atp2a2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    29693 (Atp2a2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    29693 (Atp2a2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    29693 (Atp2a2)
   04261 Adrenergic signaling in cardiomyocytes
    29693 (Atp2a2)
  09154 Digestive system
   04972 Pancreatic secretion
    29693 (Atp2a2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    29693 (Atp2a2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    29693 (Atp2a2)
   05017 Spinocerebellar ataxia
    29693 (Atp2a2)
   05022 Pathways of neurodegeneration - multiple diseases
    29693 (Atp2a2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    29693 (Atp2a2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    29693 (Atp2a2)
   05414 Dilated cardiomyopathy
    29693 (Atp2a2)
   05415 Diabetic cardiomyopathy
    29693 (Atp2a2)
Enzymes [BR:rno01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     29693 (Atp2a2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 29693
NCBI-ProteinID: NP_001104293
RGD: 2174
Ensembl: ENSRNOG00000001285
UniProt: P11507
Position
12:39733519..39782942
AA seq 1043 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECAQPATKPSCSLSACTDGISWPFV
LLIMPLVVWVYSTDTNFSDMFWS
NT seq 3132 nt   +upstreamnt  +downstreamnt
atggagaacgctcacacaaagaccgtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgaa
ttgccggctgaagaaggaaagaccttgctggaacttgtgatcgagcagtttgaagactta
ctagttagaattttattgctggcagcatgtatatctttcgttttggcttggttcgaagaa
ggtgaagaaacgattacagcctttgtagaaccttttgtaattctgcttatattggtagcc
aatgcaattgtgggtgtatggcaggagagaaacgctgaaaatgcaatagaagctcttaag
gagtatgaacctgaaatgggcaaggtgtatcgacaggacagaaagagtgtgcagcggatt
aaagcgaaagatatagttcctggggatatagtggaaattgctgttggtgacaaagttccg
gctgacattagattgacatccatcaagtctacaactctgagagttgaccagtcgattctt
acaggtgaatctgtctcggtcatcaagcatactgaccctgtccctgacccacgagctgtt
aatcaagacaaaaagaacatgctcttttctggcacaaacatcgctgctggcaaagctatg
ggagtggtggtggcgactggagtcaatactgagatcggcaagatccgggatgaaatggtt
gcaacagaacaggagagaacacccctacagcagaagctggacgagtttggggaacagctt
tccaaagttatctccctcatttgcattgcagtctggatcatcaacatcgggcatttcaat
gacccagttcatggtggctcttggatcagaggtgccatctactactttaagattgcagtg
gccctggctgttgctgccatccctgagggtctgcctgctgtcatcaccacctgcttggct
cttggaactcgaaggatggcaaagaaaaatgctattgttcgaagtctgccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagaccggcacacttaccacaaaccag
atgtccgtctgcaggatgttcattctggacaaagtagaaggtgatacttgttcccttaat
gagtttaccataactggatcaacctatgcacccattggagaagtgcaaaaagatgacaag
ccagtgaaatgccatcagtatgacgggcttgtagagttagcaacgatctgtgctctgtgt
aatgactctgctttggattacaatgaggcgaagggtgtgtatgaaaaagttggagaagcc
acagagactgctctcacgtgcctggtagagaagatgaatgtattcgacacggagctgaag
ggactttctaaaatagaacgcgccaacgcctgcaactcggtcataaaacagctcatgaag
aaggaattcacgctagagttttcacgtgatagaaaatcaatgtccgtctactgtacacca
aacaaaccgagccggacgtccatgagcaagatgtttgtgaagggtgctccagaaggtgtc
atcgacaggtgcacccacatccgagttggaagtaccaaggtccccatgacgcctggtgtt
aaacagaagattatgtctgtcattcgggagtggggcagtggcagcgacacactgcggtgc
ctggctctggccactcatgacaacccgctgaggagagaggagatgcacctggaagattct
gcgaacttcatcaaatatgagaccaatctgactttcgttggctgtgtgggcatgctggac
cctcccaggattgaagtggcctcttctgtgaagctgtgccggcaagcgggcatccgagtc
atcatgatcactggggataacaaaggcactgctgtggccatctgtcgccgcattggcatc
tttgggcaggatgaggatgtgacatcaaaggcttttacagggcgagaatttgatgaatta
agcccctcagcccagagagacgcctgcttaaatgcccgttgttttgctcgagttgaacct
tcccacaagtctaagatcgttgagttcctgcagtcctttgatgagatcacagctatgact
ggtgatggtgtgaacgacgcgcccgctctgaagaagtcggaaatcgggattgccatgggc
tcagggactgcagtggctaagacggcctctgagatggtgctggccgacgacaacttctcc
accatcgtggccgctgttgaggaggggcgcgccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggggaggtggtctgtatcttcctgacggcagccctt
gggtttcctgaagctttgattcctgtccagttactctgggtcaatctggtgacggatggt
ctgcctgccactgcgctggggttcaatcctccagatctggacatcatgaacaaaccccca
cggaacccaaaagaaccgctgatcagcgggtggctctttttccgttacctggctattggc
tgttatgttggcgctgccaccgtgggtgctgctgcgtggtggttcatcgctgctgacggt
ggtccgagagtctccttctaccagctgagtcatttcctgcagtgtaaggaggacaaccca
gacttcgaaggagtggattgtgcaatctttgagtccccgtatccgatgacaatggcactt
tctgttctagtcaccatagagatgtgcaatgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcttgtccatg
tcccttcacttcttgatcctctacgtggaacctttgccactcattttccagatcacaccg
ctgaatctgacccagtggctgatggtgctgaaaatctccctgcctgtgatcctcatggac
gagacgctcaagtttgtggcccgaaactacctggagcctggtaaagagtgtgcgcagcct
gccaccaaaccctcctgctccctgtcggcatgcaccgacggcatttcctggccctttgtg
ctgctcattatgcccctggtggtctgggtctacagcacagacactaactttagtgatatg
ttctggtcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (39)   
   RefSeq(nuc) (3)   
   GenBank (18)   
   EMBL (18)   
Protein domain (7)   
   Pfam (7)   
All databases (76)   

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