KEGG   Rattus norvegicus (rat): 297376
Entry
297376            CDS       T01003                                 
Symbol
Htra2
Name
(RefSeq) serine protease HTRA2, mitochondrial
  KO
K08669  HtrA serine peptidase 2 [EC:3.4.21.108]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04210  Apoptosis
rno04215  Apoptosis - multiple species
rno05012  Parkinson disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    297376 (Htra2)
   04215 Apoptosis - multiple species
    297376 (Htra2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    297376 (Htra2)
   05022 Pathways of neurodegeneration - multiple diseases
    297376 (Htra2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    297376 (Htra2)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    297376 (Htra2)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.108  HtrA2 peptidase
     297376 (Htra2)
Peptidases and inhibitors [BR:rno01002]
 Serine peptidases
  Family S1: chymotrypsin family
   297376 (Htra2)
Chaperones and folding catalysts [BR:rno03110]
 Other chaperones and cochaperones
  DegP / HtrA
   297376 (Htra2)
SSDB
Motif
Pfam: Trypsin_2 Trypsin PDZ_6 PDZ_2 PDZ Peptidase_S46 GRASP55_65
Other DBs
NCBI-GeneID: 297376
NCBI-ProteinID: NP_001100069
RGD: 1308906
Ensembl: ENSRNOG00000022448
UniProt: F7FLZ6 B0BNB9
Position
4:complement(117114631..117117793)
AA seq 458 aa
MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPAR
VPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLL
LWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFIVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPADVILAIGEKM
IQNAEDVYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE
NT seq 1377 nt   +upstreamnt  +downstreamnt
atggctgcgctgaaggcggggcggggtgcaaactggagccttcgggcatggcgggctttg
gggggcatcttctggaggaagggccccctgttagcccctgacctccgggctctgctgacg
tcaggaactcctgaccctcaggcccggatgacttatgggacccccagtctcccggcccgg
gtgcctttgggggtccttgcatcacgggcaaatctgacgtctgggaccccggatctctgg
gtacgactgactgtggggactccaggctctagtgaccaggaggactgcgggagccctgga
agccgtcggcgcgaatggctagcggtggcgttgggcgcagggggtgcagtgctgctgttg
ttgtggggttgggggcggggtccttccacggtgctggctgctgttcctgctccgccaccc
acctctccccggagccagtacaatttcatcgcagacgtggtggagaagacagcccctgct
gtggtctatatcgagatcctagaccggcaccctttctccggccgtgaagtccccatctca
aacggttcaggattcatagtggcttcagatgggctcatcgtaaccaacgcccacgtggtg
gctgatcggcgccgagtgcgagtgaggctacctagcggagacacttatgaggccatggtc
acagctgtggatcctgtagcagacattgccacattaaggattcaaaccaaggagcctctt
cccacactgcccctcggccgctccgctgatgtccggcaaggggagtttgttgttgccatg
ggaagtcccttcgctctgcagaacaccatcacgtccggcattgtcagctctgctcagcga
ccagccagggacctggggctccctcagaccaacgtggaatacattcagaccgatgcagct
attgactttggaaattctggtggtcccctggttaacctggatggggaggtgattggagtg
aacaccatgaaggtgacagctggaatctcctttgccatcccttctgatcgccttagggag
ttcctgcatcgcggggagaagaaaaattcctggtttggaatcagtgggtcccaacgccgc
tacattggagtgatgatgctgactctgacccccagcatccttgctgagctacagctccga
gagccaagtttccctgatgttcagcatggtgtcctcattcataaagttatcctgggctcc
cctgcacacagggctggcctgcggcctgctgatgtgatcttggccattggggagaaaatg
atacaaaatgctgaagatgtttatgaggctgttcgaacccaatcacagctggcagtgcgg
atccggcgtggaccagaaacgctgaccttatacgtgaccccagaggtcacagaataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (36)   

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