KEGG   Rattus norvegicus (rat): 298596
Entry
298596            CDS       T01003                                 
Symbol
Sdhb
Name
(RefSeq) succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor
  KO
K00235  succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00020  Citrate cycle (TCA cycle)
rno00190  Oxidative phosphorylation
rno01100  Metabolic pathways
rno01200  Carbon metabolism
rno04714  Thermogenesis
rno04932  Non-alcoholic fatty liver disease
rno05010  Alzheimer disease
rno05012  Parkinson disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05415  Diabetic cardiomyopathy
Module
rno_M00009  Citrate cycle (TCA cycle, Krebs cycle)
rno_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
rno_M00148  Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    298596 (Sdhb)
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    298596 (Sdhb)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    298596 (Sdhb)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    298596 (Sdhb)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    298596 (Sdhb)
   05012 Parkinson disease
    298596 (Sdhb)
   05014 Amyotrophic lateral sclerosis
    298596 (Sdhb)
   05016 Huntington disease
    298596 (Sdhb)
   05020 Prion disease
    298596 (Sdhb)
   05022 Pathways of neurodegeneration - multiple diseases
    298596 (Sdhb)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    298596 (Sdhb)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    298596 (Sdhb)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.5  With a quinone or related compound as acceptor
    1.3.5.1  succinate dehydrogenase
     298596 (Sdhb)
SSDB
Motif
Pfam: Fer2_3 Fer4_17 Fer4_8 Fer4_10 Fer2 Fer4_18 Fer4_9 Fer4_7
Other DBs
NCBI-GeneID: 298596
NCBI-ProteinID: NP_001094009
RGD: 1308598
Ensembl: ENSRNOG00000007967
UniProt: P21913
Position
5:158547775..158568589
AA seq 282 aa
MAAVVGVSLKRGFSATALGRVGLQFQACREAQTAAAAAPRIKTFAIYRWDPDKAGDKPRM
QTYKVDLNKCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRID
TDLGKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEDRE
KLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDEFTEERLAKLQDPF
SLYRCHTIMNCTQTCPKGLNPGKAIAEIKKMMATYKEKRALA
NT seq 849 nt   +upstreamnt  +downstreamnt
atggcggcggtggtcggggtctccttgaagcgcggcttttcggctacggctctcggcaga
gtcggcctgcagtttcaggcctgccgagaggcacagacagctgctgctgcagctcccaga
atcaaaaccttcgccatttaccgatgggacccggacaaggctggagataaacctcgaatg
cagacatacaaggtggatctgaataagtgtggaccgatggtgctggatgctctaatcaag
attaagaatgaaatcgattctactttgaccttccgaagatcatgcagagaagggatctgt
ggctcttgtgccatgaacatcaacggaggcaacacgctggcatgcacgcgcaggatcgac
acagaccttggcaaagtctcgaaaatataccctcttccgcatatgtatgtgatcaaggat
ctagtccctgacttgagtaacttctatgcacaatacaaatccattgagccctatctgaag
aagaaggatgagtcccaggagggcaagcaacagtatctgcaatccatcgaggaccgggag
aagctggacggattgtatgagtgcatcctgtgtgcctgctgcagcaccagctgtcccagt
tactggtggaacggagacaagtacctggggcctgcagttctcatgcaggcttatcgctgg
atgatcgactccagagatgaattcacagaggagcgcctggccaagctgcaggaccccttc
tctctctaccgctgccacaccatcatgaactgtacacagacctgccccaagggtctgaat
ccaggaaaagcaattgcagaaatcaagaagatgatggcgacctacaaggagaagcgggca
ttggcttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (17)   
   KEGG PATHWAY (14)   
   KEGG MODULE (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (8)   
   Pfam (8)   
All databases (57)   

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