KEGG   Rattus norvegicus (rat): 298947
Entry
298947            CDS       T01003                                 
Symbol
Pik3cg
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  KO
K21289  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00562  Inositol phosphate metabolism
rno01100  Metabolic pathways
rno04022  cGMP-PKG signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04261  Adrenergic signaling in cardiomyocytes
rno04371  Apelin signaling pathway
rno04611  Platelet activation
rno04725  Cholinergic synapse
rno04921  Oxytocin signaling pathway
rno05132  Salmonella infection
rno05145  Toxoplasmosis
rno05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    298947 (Pik3cg)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    298947 (Pik3cg)
   04072 Phospholipase D signaling pathway
    298947 (Pik3cg)
   04022 cGMP-PKG signaling pathway
    298947 (Pik3cg)
   04151 PI3K-Akt signaling pathway
    298947 (Pik3cg)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    298947 (Pik3cg)
   04062 Chemokine signaling pathway
    298947 (Pik3cg)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    298947 (Pik3cg)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    298947 (Pik3cg)
  09156 Nervous system
   04725 Cholinergic synapse
    298947 (Pik3cg)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    298947 (Pik3cg)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    298947 (Pik3cg)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    298947 (Pik3cg)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    298947 (Pik3cg)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     298947 (Pik3cg)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    298947 (Pik3cg)
SSDB
Motif
Pfam: PIK3CG_ABD PI3_PI4_kinase PI3Ka PI3K_rbd PI3K_C2 DUF4135
Other DBs
NCBI-GeneID: 298947
NCBI-ProteinID: NP_001358229
RGD: 1306468
Ensembl: ENSRNOG00000009385
Position
6:complement(54494247..54529563)
AA seq 1102 aa
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGKAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWEAESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALMVGRSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt   +upstreamnt  +downstreamnt
atggagctggagaactatgaacaacctgtggttctgagagaggacaacctccgcaggcgc
cggaggatgaagccacgcagcgcagcaggcagcctgtcttccatggagctcatccccatt
gagttcgtactgcccaccagccagcgcatcagcaagacaccggaaacggccctgctgcat
gtggctggccacggcaatgtggagcagatgaaagctcaggtgtggttacgcgcactggag
accagtgtggctgcggaattctaccaccgattaggtccggaccaattcctcctcctctac
cagaagaagggacagtggtatgagatctacgataggtaccaagtggtgcagaccctagac
tgcctacgttactggaagatgatgcacaagagccccggccagatccacgtggtacagcga
catgtaccttctgaggagaccctggctttccagaagcagctcacctccctgattggctac
gacgtcactgacatcagcaacgtgcacgatgatgagctagaattcactcgccgccgtctg
gttacgccccgcatggctgaagtggctggccgggatgccaaactctatgccatgcaccct
tgggtgacctccaaacctcttccagactacctgtcaaaaaaaattgtcaacaattgcatt
ttcattgtcatccatcgtggtaccaccagtcaaaccatcaaggtctccgcagatgatact
cctgacaccatccttcagagcttcttcaccaagatggccaagaagaagtccctaatgaat
atcccagaaagtcaaagtgagcaggattttgtgctgcgggtctgtggccgtgatgagtac
ctagtaggtgaaacgcccctcaaaaatttccagtgggtgaggcagtgcctcaagaacgga
gaggaaatacacctggtgctcgacacgcctccagacccggccctagatgaggtgaggaac
gaagaatggccgctggtggatgactgcactggagtcaccggctaccatgagcagctgacc
atccatggcaaggaccacgagagcgttttcacagtgtctttgtgggactgtgaccgaaag
ttcagggtcaagatcagaggcattgatatccctgtcttgcctcggaacaccgacctcact
gtttttgtggaagcaaatatccagcatgggcaacaagtcctctgccaaaggagaaccagc
cctaagctcttcacagaagaggtgctctggaatgtgtggctggagtttggcattaaaatc
aaagacttgcccaaaggggccctactgaacctacagatctactgctgcaaaaccccatca
ctgtccagtaaggcttccgtagagacgccaggctccgagtccaagggcaaagcccagctc
ctctattacgtgaacttgctgttgatagaccaccgcttcctcctccgccatgggggctac
gtgctccacatgtggcagatatctgggaaggcagaggaacagggcagcttcaatgccgac
aagctcacctccgcaaccaatcctgacaaggagaactcaatgtccatttccatcttgctg
gacaactactgtcaccccattgctttgcctaagcaccggcctactccggacccagaagga
gacagagttcgagctgaaatgcccaatcagcttcgaaagcaattggaggcaatcatagcc
acagatccacttaaccccctcacagcagaggacaaagaattgctctggcattttagatat
gaaagcctgaagcatccaaaggcataccctaaactattcagctcagtaaagtggggacag
caagaaattgttgccaaaacataccagctattagccagaagggagatctgggatcaaagt
gctttggatgttggcttaaccatgcaactcctggactgcaacttttcagatgaaaacgta
agggccattgcagttcagaaactggagagcttggaggacgatgacgttttacattacctt
ctccagctggtgcaggctgtgaaatttgaaccataccatgacagtgcgctggccagattc
ttgctgaagcgtggcttgagaaacaagagaattggtcacttcttattctggttcttgcga
agtgagatagcccagtccagacactatcagcagaggttcgctgtgatcctggaagcgtac
ctgcgcggctgtggcaaggccatgctacaggacttcacgcagcaggtccacgtgattgag
atgttacagaaagtcaccattgatatcaaatcactctcggctgagaagtatgatgtcagt
tcccaagttatttcacagcttaagcaaaagcttgaaagcctgcagaattccagtcttcct
gagagctttagagttccctatgatcctggactgaaagcaggtaccctggtgattgagaag
tgtaaagtgatggcctccaagaagaagcccctgtggcttgagtttaaacgtgccgatcct
acagtcctatccaatgaaaccattgggatcatctttaaacatggcgacgatctacgccaa
gacatgttgatcttacagattctacgcatcatggagtccatttgggaggctgaatctctg
gacctgtgccttctgccttacggttgcatctcaactggtgacaaaatagggatgatagag
attgtgaaggacgccacgacgattgctcaaattcagcagagcacggtgggtaacacgggg
gcattcaaagatgaagtcctgaatcactggctcaaggaaaaatgccctattgaagaaaag
tttcaggcagcagtggaaaggttcgtttactcctgtgcaggctactgtgtggccacattt
gttcttgggataggtgacaggcacaacgacaacatcatgatctcagagacaggaaaccta
tttcacatagactttggacacattcttggcaattacaagagtttcctgggcatcaataaa
gagagagtaccttttgtcctaaccccggacttcttgtttgtgatgggaacttcgggcaaa
aagacaagtccacacttccagaaattccaggatgtctgcgttagggcttacctagctctt
cgccaccacacaaacctgctgatcatcctgttctccatgatgctgatgacaggaatgccg
cagctgacaagcaaagaggacattgaatacatccgggatgccctcatggtggggagaagc
gaggaggacgccaagaagtatttccttgatcagattgaagtctgcagggacaaaggatgg
actgtgcagtttaactggttcctccatcttgttcttggcatcaagcaaggagagaaacac
tccgcttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (6)   
   Pfam (6)   
All databases (45)   

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