KEGG   Rattus norvegicus (rat): 299284
Entry
299284            CDS       T01003                                 
Symbol
Dicer1
Name
(RefSeq) endoribonuclease Dicer
  KO
K11592  endoribonuclease Dicer [EC:3.1.26.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    299284 (Dicer1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:rno03036]
    299284 (Dicer1)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Gene silencing
   RISC (RNA-induced silencing complex)
    299284 (Dicer1)
   microRNA pathway
    RISC loading complex
     299284 (Dicer1)
SSDB
Motif
Pfam: Dicer_platform Dicer_dsRBD Ribonuclease_3 Dicer_PBD Ribonucleas_3_3 Dicer_dimer PAZ Helicase_C ResIII DEAD
Other DBs
NCBI-GeneID: 299284
NCBI-ProteinID: NP_001414144
RGD: 1309381
Ensembl: ENSRNOG00000010711
Position
6:complement(129392298..129457252)
AA seq 1918 aa
MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNT
IVCLNTGSGKTFIAVLLTKELAHQIRGDLSPHAKRTVFLVNSANQVAQQVSAVRTHSDLK
VGEYSNLEVNASWTKERWSQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLA
ILDHPYREIMKLCDSCPSCPRILGLTASILNGKCDPDELEEKIQKLEKILKSGAETATDL
VVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALDFINDCNVSVHSKERDSTLISK
QILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCE
EYFSPASLDLKYVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDD
DEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFIT
GHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLP
TEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDGAEAD
VHAVVDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPD
GTFYSTLYLPINSPLRASIVGPPMGCVRLAERVVALICCEKLHKIGELDEHLMPVGKETV
KYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTP
LPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQ
QMLELVTRLHQYIFSHILRLEKPALEFQPAGAESAYCVLPLNVVNDSSTLDIDFKFMEDI
EKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF
PSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKR
KAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGV
GVRSLPADFRYPNLDFGWKKSIDSKSFISTCNSSLAESDNYCKHSTTVVPENAAHQGATR
PSLENHDQMSVNCKRLPAESPAKLQSEVSVDLTAINGLSYNKSLANGSYDLVNRDFCQGN
QLTYFKQEIPVQPTTSYPIQNLYNYENQPTPSNECPLLSNKYLDGNANTSTSDGSPAGSP
RPAMMTAVEALEGRTDSEQSPSVGHSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGD
SFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKQGLPSRMVVSIFDPPVNW
LPPGYVVNQDKSNSEKWEKDEMTKDCLLANGKLGEDCEEEEEEELAWRAPKEEAEYEDDL
LEYDQEHIQFIDSMLMGSGAFVKKIPLSPFSTSDSAYEWKMPKKASLGSVPFSSDLEDFD
YSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADC
VEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSRDKASYPAQENSSSQQKSPSGSCA
AAVSPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFENFEKKINYIFKNKAYLL
QAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTI
FASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEV
PKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPET
AKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPLVPNS
NT seq 5757 nt   +upstreamnt  +downstreamnt
atgaaaagccctgctttgcagcccctcagcatggcaggcctgcagctcatgacccctgct
tcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataac
atttatacgccaagaaaataccaggttgagctgctggaagcagctctggaccacaacacc
attgtgtgcttgaacactggctcagggaagacgttcatcgccgtcctgctcaccaaagag
ctggcccaccagatcaggggcgacctcagtccgcatgcaaaaaggactgtgttcctcgtc
aactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcactcagatctcaag
gttggggagtactcaaacctcgaagtgaatgcatcttggacaaaagagagatggagccaa
gagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaa
aatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgca
attctagaccacccctatcgtgaaattatgaagctctgtgacagttgtccatcatgccct
cgaattttgggactaactgcttccattttaaatgggaaatgtgacccagacgaattggaa
gaaaagattcagaaactggaaaagattctcaagagtggcgctgagaccgcaactgacctg
gtggtcctggacagatacacttctcagccttgtgagattgtggtggattgcggaccattt
actgacagaagtgggctttatgaaagactgctgatggagttagaagaagcacttgacttt
atcaatgactgtaatgtatctgtacattcaaaggaaagagattctactttgatttccaaa
caaatcctctcagactgccgtgcagtgctggtcgtcctgggaccctggtgtgcagataaa
gtagcggggatgatggtaagagaacttcagaagtacatcaaacatgagcaagaggagcta
cacaggaagttcttattgtttacagacactctgctaaggaaaatacatgcactgtgtgaa
gagtacttctcccctgcctcacttgacctgaagtatgtaactcccaaagtcatgaaactg
ctcgagatcctgcgcaaatacaagccctatgagcgacagcagttcgaaagtgttgagtgg
tacaataacaggaatcaggataattatgtgtcctggagtgattctgaggacgatgacgat
gatgaagaaattgaagaaaaagaaaagccagagacaaattttccttctccatttaccaat
attttatgtggaattatttttgtggaaagaagatacacagcagttgtcctaaacagattg
ataaaggaagctggcaaacaagatccagagctggcttatatcagcagcaactttataact
gggcatggcattggaaagaaccagcctcgcagcaagcagatggaggcggagttcagaaag
caagaggaggtacttaggaaatttcgagcacatgagaccaacctgctcattgcaacaagt
gttgtagaagagggtgtggacattcccaagtgcaatttggtggttcgttttgatttgccc
acagagtatcgttcttacgttcagtctaaaggacgggcacgagcaccgatctctaattat
gtaatgttagcagacacagacaaaataaagagctttgaagaagacctcaagacctacaaa
gctatagaaaagatcttaagaaacaagtgttcaaagtcagtggatggtgctgaggctgac
gtccatgctgttgtagatgatgatgatgttttcccgccatatgtactgaggcctgatgat
gggggtcctcgagtcacaatcaacactgccattggacacatcaacagatattgtgctcga
ttaccaagtgatccgtttacgcatctagctcccaaatgtagaacccgagaattgcctgat
ggtacattttattcaactctttatcttccgattaactcacctcttcgagcctccattgtt
ggtccaccgatgggctgtgtacggctggctgagagagtggtagctctcatctgctgtgaa
aaactgcacaaaattggtgaactggatgaacatttgatgccagttgggaaagagactgtt
aagtatgaagaagaacttgacttacatgatgaagaggagaccagcgttccagggagacca
ggatccacaaaacgaaggcagtgctaccccaaagcaattccagagtgcttgagggagagt
taccccaaacccgatcaaccctgttacctgtatgtgataggaatggtcttaaccaccccc
cttcctgatgagctcaacttcaggcggcggaagctctaccctcctgaggacaccaccaga
tgctttgggatcctgacagccaaacccatacctcagatccctcactttcctgtgtatact
cgctctggagaggtcaccatatccatcgagctgaagaagtctggtttcacactgtctcaa
caaatgcttgagctggttacgagactgcaccagtacatattctcacacattctccggctc
gagaagcctgccctggagtttcaacccgcgggcgctgagtcagcgtactgtgttctacct
cttaacgtcgttaatgactccagcactttggacattgactttaaattcatggaggatatt
gagaagtctgaagctcgtataggcattcccagcactaagtattcaaaggaaacaccgttt
gtttttaagttagaagattaccaagatgcagttatcattccaagataccgcaattttgat
cagcctcatcgattttatgtagctgatgtgtatactgatcttaccccactcagtaaattt
ccttcccctgaatatgaaacttttgcagaatattataaaacaaagtataaccttgacctg
accaatctcaaccagccactgctggatgttgaccacacatcttccagactgaaccttcta
acccctcggcatttgaatcagaaggggaaagcacttcctctaagcagtgctgaaaagagg
aaagccaaatgggaaagtctgcagaacaaacagatactggttccggaactctgtgctata
catccaatcccagcatcactgtggagaaaagcagtttgtctccccagcatactgtatcgc
cttcactgccttctgactgcggaggagctcagagctcagacagccagcgatgctggcgta
ggagtcagatcacttccggccgattttagataccctaacttagacttcgggtggaaaaag
tctattgatagcaagtctttcatctcaacctgtaactcctcgttggctgagagtgataat
tactgtaagcacagcacaactgtagtccctgaaaatgctgcacatcaaggtgctactaga
ccctccttagaaaaccatgaccaaatgtctgtgaactgcaaaaggttgcccgccgagtca
cctgctaagctccaaagtgaggtttcagtggatcttacagcaatcaatggtctttcttac
aataaaagccttgccaatggcagttatgatttagttaacagagacttttgccaaggaaat
cagctgacttacttcaagcaggaaatacctgtacaaccaactacctcatatcccattcag
aatttatacaattatgagaaccagcccacgcccagcaatgaatgtcctctactgagtaat
aagtaccttgatgggaacgctaacacatctacctcagacggaagccccgcagggtcccca
aggcctgccatgatgactgctgttgaagcactggagggcaggacagactctgagcagagc
ccttctgtggggcactcctcaaggactctcggccccaacccaggactgattcttcaggct
ttgacactgtcgaacgctagcgatgggtttaacctagagcggcttgagatgcttggcgac
tccttcttaaagcacgctatcaccacgtatctgttttgcacataccctgatgctcatgag
ggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaacctgtaccgccttggc
aagaagcagggactgcccagccgcatggtggtgtcgatatttgatcctcctgtgaattgg
cttcctcctggttatgtggtaaaccaagacaaaagtaactcagagaaatgggaaaaggat
gaaatgacaaaagactgcttgctggctaatggcaaactgggtgaggactgtgaggaggag
gaggaggaggagctggcgtggagggctcccaaggaggaggctgagtatgaagacgacctc
ctggagtatgaccaggagcacattcagtttatagacagcatgctaatgggctcaggggcc
tttgtgaagaaaatccctctttcccccttttccacctctgattctgcatatgaatggaaa
atgcccaaaaaggcctccctgggcagtgtgccgttttcctcagaccttgaggattttgat
tacagctcttgggatgcaatgtgctatctggatcctagcaaagccgttgaagaggatgac
tttgtggtaggtttctggaatccatcagaagaaaactgtggcgtggacacagggaagcag
tccatttcttacgacttgcacactgagcagtgcatcgcggacaagagcatagcggactgc
gtggaggccctgctgggctgttacttaaccagctgtggtgagagggctgctcagctcttc
ctctgctcgctggggctgaaggtgctcccagtcatcaaaaggaccagccgggacaaggcc
tcgtaccctgctcaggagaactcaagcagccaacagaagagcccttcagggagctgtgct
gctgcagtcagtccccgctcctctgcagggaaagacttggagtatggctgcttgaagatc
ccgccaaggtgtatgtttgaccatccagatgcagagaaaaccctgaaccacctcatatct
gggtttgaaaattttgaaaagaaaatcaactacatattcaagaataaggcttaccttctg
caggcttttacacatgcctcctaccactacaacactattactgattgttaccagcgctta
gaattcctgggagatgcgattttggactacctcataaccaagcacctttatgaagaccca
cggcagcattctccaggggtcctgactgacctgcgctctgccctggtcaataacaccatc
tttgcgtcgctggctgtgaagtatgactaccacaagtactttaaagccgtctctcctgag
ctcttccacgtcattgatgacttcgtgcagtttcagctggagaagaacgagatgcaagga
atggactctgagcttaggagatccgaggaggatgaggagaaagaagaggatattgaagtc
cccaaggccatgggagacatttttgagtctcttgctggtgccatttatatggacagtggg
atgtccctggaggtggtctggcaggtgtactatccgatgatgcggcctctaatagaaaag
ttttctgcaaatgtgcctcgttctccggtaagagaattgcttgagatggaaccagaaact
gccaagtttagcccagcggagagaacttacgatgggaaggtcagagtcaccgtggaagtg
gtgggaaaggggaagtttaaaggtgtcggccggagctacaggatcgcaaagtctgctgca
gcacgaagagccctccgcagcctcaaagctaaccagcctctggttcctaacagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (2)   
   RefSeq(pep) (8)   
DNA sequence (10)   
   RefSeq(nuc) (8)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (40)   

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