KEGG   Rattus norvegicus (rat): 301005
Entry
301005            CDS       T01003                                 
Symbol
Impdh2
Name
(RefSeq) inosine-5'-monophosphate dehydrogenase 2
  KO
K00088  IMP dehydrogenase [EC:1.1.1.205]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01232  Nucleotide metabolism
Module
rno_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    301005 (Impdh2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    301005 (Impdh2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    301005 (Impdh2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.205  IMP dehydrogenase
     301005 (Impdh2)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   301005 (Impdh2)
  Exosomal proteins of breast cancer cells
   301005 (Impdh2)
SSDB
Motif
Pfam: IMPDH NMO CBS FMN_dh His_biosynth NanE ThiG Dus Glu_synthase G3P_antiterm B12-binding YceG_bac DUF561 DHO_dh
Other DBs
NCBI-GeneID: 301005
NCBI-ProteinID: NP_954530
RGD: 735092
Ensembl: ENSRNOG00000031965
UniProt: Q6P9U9
Position
8:118135204..118139892
AA seq 514 aa
MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMT
KREDLVVAPAGVTLKEANEILQRSKKGKLPIVNESDELVAIIARTDLKKNRDYPLASKDT
KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVI
GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
AMMYSGELKFEKRTSSAQVEGGVHGLHSYEKRLF
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggcggactacctgattagcggaggcacttcttacgtgccagacgacgggctcaccgca
cagcagctcttcaactgcggggacggcctgacctacaatgactttctcattcttcctgga
tatatcgacttcactgcggaccaggtggacttgacctctgctctaaccaagaagattact
ctgaagacccccttggtttcctcacctatggacactgtcacggaggctggaatggccatc
gcaatggcgcttacaggaggcattggcttcatccaccacaactgcacacctgaattccag
gccaatgaagttcggaaagtgaagaaatatgaacagggattcatcactgaccctgtggtc
cttagccccaaggatcgtgtgcgcgatgtttttgaggccaaagccaggcatggcttctgt
ggtatccccatcacagataccggccggatggggagtcgattggtgggcatcatctcctcg
agggacattgacttcctcaaggaggaagagcatgatcgcttcttggaagagatcatgact
aagagagaagatttagtggtagcccctgccggcgtcactctaaaagaagcaaatgaaatt
ctgcagcgcagtaaaaagggaaagttgcccattgtgaatgagagtgatgagctggtagcc
atcatcgcccggacagacctcaagaagaatcgtgactacccactggcttccaaagatacc
aaaaagcaactactgtgtggggcagccattggcacccatgaggatgacaagtatcggctg
gacttactggcccttgctggtgtggatgtggtagttttggactcttcccagggaaactcc
attttccaaatcaatatgatcaagtacatcaaggaaaaataccccaatctccaggtcatc
ggaggcaatgtagtcactgctgctcaagccaagaacctcatcgacgcaggtgtggacgct
ctgcgagtcggcatgggaagtggttccatctgcatcacccaggaagtgttggcctgtggg
cgaccccaagcaacagcagtatacaaggtctctgagtatgcccgtcgcttcggtgtccct
gttattgctgatggaggaatccagaatgtgggtcatattgccaaagctttggctcttggg
gcctctacagtcatgatgggctccctcttggctgccaccactgaggcccctggtgagtac
ttcttctccgatgggatccggctgaagaagtatcgtggtatgggctctcttgatgccatg
gacaaacacctcagcagccagaaccgatatttcagtgaagctgacaagatcaaagtggcc
caaggagtttcaggggcagtgcaggacaaagggtctatccacaagtttgtcccttatttg
attgctggcatccagcattcctgtcaggacattggtgccaagagcttaacccaagtcaga
gccatgatgtactcgggggaacttaaatttgagaagagaacgtcctcagctcaggtggaa
ggtggcgttcacggcctccattcgtatgagaaacggctcttctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (14)   
   Pfam (14)   
All databases (47)   

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