KEGG   Rattus norvegicus (rat): 301458
Entry
301458            CDS       T01003                                 
Symbol
Ndufs1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
  KO
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00190  Oxidative phosphorylation
rno01100  Metabolic pathways
rno04714  Thermogenesis
rno04723  Retrograde endocannabinoid signaling
rno04932  Non-alcoholic fatty liver disease
rno05010  Alzheimer disease
rno05012  Parkinson disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05415  Diabetic cardiomyopathy
Module
rno_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    301458 (Ndufs1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    301458 (Ndufs1)
  09159 Environmental adaptation
   04714 Thermogenesis
    301458 (Ndufs1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    301458 (Ndufs1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    301458 (Ndufs1)
   05012 Parkinson disease
    301458 (Ndufs1)
   05014 Amyotrophic lateral sclerosis
    301458 (Ndufs1)
   05016 Huntington disease
    301458 (Ndufs1)
   05020 Prion disease
    301458 (Ndufs1)
   05022 Pathways of neurodegeneration - multiple diseases
    301458 (Ndufs1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    301458 (Ndufs1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    301458 (Ndufs1)
Enzymes [BR:rno01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     301458 (Ndufs1)
SSDB
Motif
Pfam: Molybdopterin Fer2_4 NADH-G_4Fe-4S_3 NADH_dhqG_C Fer2
Other DBs
NCBI-GeneID: 301458
NCBI-ProteinID: NP_001005550
RGD: 1359670
Ensembl: ENSRNOG00000011849
UniProt: Q66HF1 A6IPF8
Position
9:complement(72040286..72073605)
AA seq 727 aa
MLRIPVKRALIGLSKSPKGYVRSTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFEGKAVAAIAGGLVDAEALVALKDLLNK
VDSDTLCTEEIFPNEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHEFSKVLNAAKKPMVVLGSSA
LQRDDGAAILAAVSSIAQKIRVASGAAAEWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKLLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLGEVSPNLVRYDDVE
EANYFQQASELAKLVDQEFLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq 2184 nt   +upstreamnt  +downstreamnt
atgttaaggatacctgtaaaaagggccttgataggcctttctaagtctcctaaaggatat
gttcgatcaactggcacagcagcaagtaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaaccactgtcctgcaggcctgcgagaaggttggcatgcaaatc
cctcgattctgttaccatgaaaggttgtctgtagctggaaattgcaggatgtgcctggta
gagattgagaaagctccaaaggttgttgctgcttgtgctatgcctgttatgaagggctgg
aatatcctgacaaactcagaaaaatctaagaaagccagagaaggtgtgatggagttttta
ttagcaaatcacccattggattgtcctatttgtgaccagggaggtgaatgtgatctacag
gaccagtccatgatgtttggaagtgataggagccgatttctagaggggaagcgtgctgtg
gaggacaagaacattgggcccctggtaaagaccatcatgactagatgcatacagtgtacc
cgctgcatcaggtttgcaagtgaaattgcaggagtagatgatttgggaacaacggggaga
ggaaatgacatgcaagttggaacatacattgagaaaatgttcatgtctgaactgtctggg
aacatcattgatatctgccctgtcggggccctaacctctaagccttatgcctttactgcc
cggccttgggaaacaagaaagacagagtccattgatgtaatggatgcagtgggaagtaac
attgtggttagcacaagaactggagaggtaatgaggattttgccaagaatgcatgaagat
attaatgaagaatggatctctgataaaaccagatttgcctatgatggactgaaacggcaa
agacttaccgaaccaatggtcagaaatgaaaaggggcttttaacttatacctcctgggaa
gatgcactctctcgtgtagctggaatgttacagagttttgaaggcaaggctgtggcagca
attgcaggtggcttggtggatgctgaagccttggtagctctgaaagatttgcttaataaa
gttgactctgacaccttatgcactgaagagatcttccccaatgaaggagctggcacagat
ttacgttccaattatcttctcaataccacaattgccggtgtggaagaagcagatgttgtt
cttctagttggtacaaatccacgttttgaggcaccgctgtttaatgctagaatcagaaag
agctggctgcataatgacttaaaagtggccctaataggcagtccagtagacctcacttac
agatacgaccatctaggagactctcccaaaattctgcaagacattgcttcagggaatcat
gaattcagcaaggtcttaaacgcagctaaaaaaccaatggtggttttaggcagttctgca
ctccagagagatgatggggcagcaattcttgcagctgtgtccagcattgcacaaaagatt
cgggtggcaagtggtgctgctgcagagtggaaagttatgaatattctgcataggattgca
agccaggtagctgctttggaccttggctataaacctggggtagaagcaattaggaagaac
ccacccaaactgctgtttcttctgggagcagatggaggttgtatcacccggcaggacttg
ccaaaggattgtttcattgtttatcaaggacatcatggtgatgttggtgctcccatagct
gatgttattctcccaggggctgcttacacagaaaagtctgctacttacgtcaatactgag
ggcagagctcaacaaaccaaagtagcagtgacacctcctggcttggcaagagaagactgg
aaaatcataagagctctctctgagattgcaggtatcactctcccatatgatactctggat
caagtgagaaaccgtctcggagaagtctctcctaacctggttcgatatgatgatgttgaa
gaagctaattactttcaacaagcaagtgagcttgccaagctagtagaccaggaatttctt
gctgacccactggttccacctcagctaactataaaagacttctatatgacagattcaatt
agcagagcctcacagacaatggccaagtgtgtcaaagccgtcacagaaggcgctcaggca
gtagaggagccatccatatgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (13)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (5)   
   Pfam (5)   
All databases (44)   

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