KEGG   Rattus norvegicus (rat): 303333
Entry
303333            CDS       T01003                                 
Symbol
Slc46a1
Name
(RefSeq) proton-coupled folate transporter
  KO
K14613  MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01523  Antifolate resistance
rno04977  Vitamin digestion and absorption
rno04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    303333 (Slc46a1)
   04978 Mineral absorption
    303333 (Slc46a1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    303333 (Slc46a1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    303333 (Slc46a1)
Transporters [BR:rno02000]
 Solute carrier family (SLC)
  SLC46: Folate transporter
   303333 (Slc46a1)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
    303333 (Slc46a1)
SSDB
Motif
Pfam: MFS_1 Sugar_tr
Other DBs
NCBI-GeneID: 303333
NCBI-ProteinID: NP_001013991
RGD: 1309472
Ensembl: ENSRNOG00000010291
UniProt: Q5EBA8 A6HH50
Position
10:63859551..63865987
AA seq 459 aa
MEGRVSPVGSSHRLLTAAVLFRGPVEPLVFLANFALVLQGPLTTQYIWHRISTELGYNGT
RHRENCGNQSADPVLKEVETLTSHWTLYMNVGGFLVGLFWSTLLGAWSDRVGRRPLLVLA
SLGLLLQAVVSIFVVQLQLHIGFFVLGRALCALLGDFNGLLAASFASVADVSSNHSRTFR
MALLEACIGVAGTLASLLGGHWLRAQGYANPFWLALAVLIVMTLYAAFCFGETVKEPKST
RLFTLRHHRSIVQLYVVPAPEKSRMHLALYSLAIFVVVTVHFGAQDILTLYELSTPLCWD
SKLIGYGSAAQHLPYLTSLLGLRLLQFCLADTWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVTTPVIRAKLSKLVSESEQGALFSAVACVNSLAMLMASGIFNSLYPATLNF
MKGFPFLLGAGLLFIPAILIGVLEKVNPHPEFQQFPQNS
NT seq 1380 nt   +upstreamnt  +downstreamnt
atggaggggcgcgtgagccccgtgggctcgtcccaccgtctcctcaccgccgccgtgctg
ttccgcggccccgtggagcccctcgttttcctagccaactttgcgctggttctacaggga
ccgctcaccacacagtacatttggcaccgcatcagcaccgagctcggatacaatggcacc
cgccaccgggagaactgtggcaaccagagcgcggatcccgtcctgaaggaagtggagacc
ctgacatcccactggaccctctacatgaacgtgggaggcttcctggtgggactcttctgg
tccaccctcctgggagcctggagtgaccgcgtgggtcgccgcccattgctggtgctggcc
tctcttggtctgctgctccaggccgtggtgtccatctttgtggtgcaactacaactgcac
atcgggttcttcgtgctcggccgagccctttgtgcccttctgggagatttcaacggcctt
cttgctgctagctttgcctctgtggctgatgttagctctaatcacagtcgcaccttccgg
atggctctgctggaagcatgcattggtgtggccgggaccctggcaagccttcttgggggt
cactggctccgggcccagggttatgccaaccctttctggctggctttggctgtgctgatc
gttatgactctatatgcagcattctgttttggtgagacagtgaaggagccaaagtccacg
aggcttttcacgctccgccatcaccgatccattgtccagctgtatgtggtcccagcccca
gagaagtccaggatgcatctagccctgtactcattggccatattcgtggtggtcactgtg
cactttggggctcaagacatcctgacgctctatgagctaagcacacccctctgctgggac
tccaagctgattggctatggctcagcagcccagcacttaccctacctcaccagcctgctg
ggcctgagacttctgcagttctgcctggccgacacctgggtggctgagattggcctggcc
ttcaacatcctgggaatggtggtctttgcgttcgcaaccatcacacccctcatgttcaca
gggtacggattactcttcctgtcattggtcactacgcctgtgatccgggccaagctctcc
aagctagtgagcgagtcggagcagggtgctctcttttcggctgtggcctgtgtgaatagc
ttggccatgttgatggcctccggcatcttcaactcactctacccggccactctgaacttc
atgaagggcttccccttcctcctgggagctggcctcctctttatcccggccattctgatt
ggggtactggagaaggttaatccacacccagagttccagcagtttcctcagaactcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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