KEGG   Rattus norvegicus (rat): 303604
Entry
303604            CDS       T01003                                 
Symbol
Map3k3
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04722  Neurotrophin signaling pathway
rno04912  GnRH signaling pathway
rno05166  Human T-cell leukemia virus 1 infection
rno05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    303604 (Map3k3)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    303604 (Map3k3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    303604 (Map3k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    303604 (Map3k3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    303604 (Map3k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    303604 (Map3k3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     303604 (Map3k3)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: STE group
  STE11 family
   303604 (Map3k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 303604
NCBI-ProteinID: NP_001100528
RGD: 1304575
Ensembl: ENSRNOG00000061424
UniProt: A6HK01 A0A0G2K8Y1
Position
10:91519976..91588651
AA seq 626 aa
MDEQEALDSIMKDLVALQMSRRPRVSGYETMKNKDTGHPNRQSDVRIKFEHNGERRIIAF
SRPVRYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSASMKSLRILL
LSQDRNHTSSSPHSGVSRQVRVKPSQSAGDINTIYQAPEPRSRHLSVSSQNPGRSSPPPG
YVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSLDRSADSPSF
RKSQMSRARSFPDNRKECSDRETQLYDKGVKGGTYPRRYHVSVHHKDYNDGRRTFPRIRR
HQGNLFTLVPSSRSLSTNGENMGAAVQYLDPRGRLRSADSENALTVQERSVPTKSPSAPI
NWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQ
HERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYL
HSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVIS
GEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFL
RRIFVEARQRPSAEELLTHHFAQLVY
NT seq 1881 nt   +upstreamnt  +downstreamnt
atggatgaacaagaggcattagactcaatcatgaaggacctggtggccctccagatgagc
cgacgtccccgggtgtctggatatgagaccatgaagaacaaggacacaggtcacccaaac
aggcagagtgacgtcagaatcaagtttgaacacaatggggagagacgaattatagcattc
agccggcctgtgagatatgaagatgtggaacacaaggtgacaacggtctttgggcagcct
cttgatttgcattatatgaataatgagctctccatcctgttgaaaaaccaagatgatctc
gataaagcaattgacattttggatagaagcgcgagtatgaaaagccttaggatactactg
ttatcccaagacagaaaccatactagttcctctccccactctggagtgtccaggcaggtt
cgggtcaagccttcccagtctgcaggggatataaataccatctaccaagctcctgagccc
agaagcaggcacctctctgtcagctcccagaaccctggccgaagctctcctccccctggt
tatgtacctgagcgacaacagcacattgcccggcagggatcatatacgagcatcaatagt
gaaggtgaattcatcccagagaccagcgagcagtgcatgctagatcccctgagcagtgcc
gaaaattccttgtcaggaagctgccaatccttggacaggtcagcagacagcccatctttc
aggaaatcacaaatgtcccgagcccggagcttcccagacaacagaaaggaatgctcggat
cgggagacccagctctatgataaaggagttaaaggcggaacctatcccaggcgttaccat
gtatctgtgcatcataaagactacaatgatggcagaagaacgtttccccgaatacgacgg
caccagggcaacctattcactctggtgccctcaagtcgctccttgagcacaaatggcgag
aacatgggtgccgctgtgcagtacttggacccccgcgggcgcctacggagtgcagacagt
gaaaatgccctcactgtgcaggaaagaagtgtgccaaccaagtctcctagtgctcccatc
aattggcgtcgggggaagctcctgggtcaaggtgccttcggcagggtctacttatgctat
gatgtggacacaggacgtgaacttgcttctaagcaggttcagtttgacccagatagtcct
gagactagcaaggaggtgagtgctctggagtgcgagatccagttgctgaagaacttgcag
catgagcgcatcgtgcagtactatggctgcctgcgggaccgtgctgagaagatcctcacc
atctttatggagtatatgccagggggctctgtaaaagaccagttgaaggcctacggagct
ctgacggagagtgtgacccgcaagtatacacggcagatcctggagggcatgtcctacctg
cacagcaacatgatcgtgcatcgtgacatcaagggagccaatatcctccgagactcggct
gggaatgtgaagcttggggattttggggccagcaaacgcctgcaaaccatctgcatgtca
gggacaggcatgcgctctgtcactggcacaccctactggatgagtcctgaagtcatcagt
ggcgagggctatggaagaaaggcagatgtgtggagcctgggctgtaccgtggtggagatg
ctgacagagaaaccaccttgggcagagtatgaagctatggctgccattttcaagattgcc
acccagcctaccaatcctcagctgccctctcacatctcagaacacggcagggacttcctg
aggcgcatatttgtggaagctcgtcagagaccctcggctgaggagctgctcacacaccac
tttgcacagctagtgtactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (6)   
   Pfam (6)   
All databases (30)   

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