KEGG   Rattus norvegicus (rat): 303614
Entry
303614            CDS       T01003                                 
Symbol
Smurf2
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF2
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04120  Ubiquitin mediated proteolysis
rno04137  Mitophagy - animal
rno04144  Endocytosis
rno04340  Hedgehog signaling pathway
rno04350  TGF-beta signaling pathway
rno04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    303614 (Smurf2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    303614 (Smurf2)
   04350 TGF-beta signaling pathway
    303614 (Smurf2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    303614 (Smurf2)
   04137 Mitophagy - animal
    303614 (Smurf2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    303614 (Smurf2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    303614 (Smurf2)
   04121 Ubiquitin system [BR:rno04121]
    303614 (Smurf2)
   03029 Mitochondrial biogenesis [BR:rno03029]
    303614 (Smurf2)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     303614 (Smurf2)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    303614 (Smurf2)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    303614 (Smurf2)
Ubiquitin system [BR:rno04121]
 Ubiquitin ligases (E3)
  HECT type E3
   303614 (Smurf2)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    303614 (Smurf2)
SSDB
Motif
Pfam: HECT WW C2 GpA_nuclease
Other DBs
NCBI-GeneID: 303614
NCBI-ProteinID: NP_001100531
RGD: 1310067
Ensembl: ENSRNOG00000014623
UniProt: A6HK62 F1M3F2
Position
10:complement(92261516..92362185)
AA seq 748 aa
MSNPGGRRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPK
WNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKL
GPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHIT
RTTQWERPTRPASEYSSPGRPLSCFVDENTPITGTNGATCGQSSDPRLAERRVRSQRHRN
YMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLP
PGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVSLCPDDT
ECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWK
RLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL
SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEND
ITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLA
LQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKANTRLKHCTPDSNVVKWFWKAV
ELFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI
DIPPYESYEKLYEKLLTAIEETCGFAVE
NT seq 2247 nt   +upstreamnt  +downstreamnt
atgtctaaccccggaggccggaggaacgggcccgtcaagctgcgcctgacagtactctgt
gcaaaaaacttggtgaaaaaggattttttccgactccctgatccgtttgctaaggtggta
gttgatggttctgggcaatgccattctacagatactgtgaagaacacacttgatccaaag
tggaatcagcattatgacctgtatattgggaagtctgattccgtcacgatcagcgtgtgg
aatcataagaagatccataagaagcaaggtgctggatttcttggttgtgttcgtcttctt
tccaatgccatcaatcgcctcaaagacactggctatcagaggttggatttatgcaaactg
gggccaaatgacaatgatacagttcgaggacaaattgtagtaagtcttcaatccagagac
cgaataggcacgggaggacaagttgtggactgcagtcgtttgtttgataatgatttacca
gacggttgggaagaaaggcgaactgcctctggaagaatccagtatctaaaccacatcaca
agaactacacagtgggaacgcccaacaagaccggcgtcagaatattctagtcctggcagg
cctcttagctgctttgtggatgagaatactccaattactggaacaaatggtgcaacatgt
ggacagtcttcagatcccagactagcagagaggagagtccggtctcagcgacatagaaat
tacatgagcaggacacacttacacactcctccagacctacccgaaggctatgaacagagg
acaacacaacagggtcaggtatatttcttacatactcagactggcgtgagcacgtggcat
gatccacgagtgcctagggatcttagcaacatcaattgtgaagagctcggtcctctgcct
cctgggtgggagatccgcaataccgcgacaggcagagtttatttcgtggaccataacaac
agaacaacacagtttacagatcctcgtctctctgctaacttgcatttagttttaaatcgt
cagaaccagttgaaagaccaacagcaacagcaagtggtgtcgttgtgtcccgatgacact
gagtgtctgacagtgccaaggtacaagcgagacttggttcaaaaactaaagatcttgcgg
caagaactttcccaacagcagcctcaagctggccactgccgcattgaggtgtcaagggaa
gagatttttgaggaatcatatcgacaagtcatgaaaatgagaccaaaggatctatggaag
cgattaatgataaaatttcgaggagaagaaggccttgactatggaggagttgccagggaa
tggttgtatctcctgtcgcatgaaatgttgaatccttactacggtctcttccagtattca
agagatgatatctacacgttacagatcaatcccgattctgcagttaatccggagcatttg
tcctatttccactttgttggacgaataatgggaatggctgtattccatggacattatatt
gatggtggtttcacattacctttttataaacagttgcttgggaagtcaattactttggac
gacatggagctagttgatccagaccttcataatagtttggtgtggatacttgaaaatgat
atcacaggtgttctggaccataccttctgtgttgaacataacgcatatggtgaaattatt
cagcatgaactcaaaccaaatggcaaaagtattcctgttactgaagaaaataaaaaagaa
tatgtcaggctttacgtaaactggagattcctccgaggcattgaagctcagttcctggca
ctacagaagggatttaatgaagtcattccacagcatctgctgaagacatttgatgagaag
gagctggagctcattatctgtgggcttggcaaaattgacgtgagcgactggaaggccaac
acccggttaaagcactgcaccccagacagcaacgtcgtcaagtggttttggaaagctgtg
gagctttttgatgaggagagacgagcacggctgctccagtttgtgacagggtcctctcga
gtgcctctgcagggcttcaaagcactccaaggtgccgcgggcccacggctctttaccata
caccagattgatgcctgcacgaacaacctgccaaaagcccacacttgtttcaatcgaata
gacattccgccctatgagagctatgagaagctctacgaaaagctgctaacagccatcgag
gagacctgtggctttgctgtggagtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (2)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (4)   
   Pfam (4)   
All databases (33)   

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