KEGG   Rattus norvegicus (rat): 304573
Entry
304573            CDS       T01003                                 
Symbol
Pole
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
  KO
K02324  DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03030  DNA replication
rno03410  Base excision repair
rno03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    304573 (Pole)
   03410 Base excision repair
    304573 (Pole)
   03420 Nucleotide excision repair
    304573 (Pole)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:rno03032]
    304573 (Pole)
   03400 DNA repair and recombination proteins [BR:rno03400]
    304573 (Pole)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     304573 (Pole)
DNA replication proteins [BR:rno03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    304573 (Pole)
DNA repair and recombination proteins [BR:rno03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      304573 (Pole)
SSDB
Motif
Pfam: DUF1744 DNA_pol_B_exo1 DNA_pol_B DNA_pol_B_exo2 RNase_H_2 APP_N
Other DBs
NCBI-GeneID: 304573
NCBI-ProteinID: NP_001100622
RGD: 1594540
Ensembl: ENSRNOG00000037449
UniProt: D3Z8X4
Position
12:complement(52005155..52053761)
AA seq 2283 aa
MVLRNSGRRHPEPGADSEGSRDDGPSSSVSALKRLERSQWTDKMDLRFGFERLKEPGERT
GWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIAARKGCDREVSSFL
SKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQ
DHASDEYTTMLSSILQGGSLITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHV
AHWYNVRFRGNAFPVEIARRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMV
TYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVC
EQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPG
ATCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
RRLADYCRKAYKKIHMTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNVKKPKLTISYPGAMLNIM
VKEGFTNHQYQELTEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYASVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQA
SENSLSLCTPDMEDFGLTKPYHSTVPVATKRKRVWESQKESQDITLTVPWQEVLGQPPSL
GTTQEEWLVWLQFHKKKWQLQAQQRLARRKKQRLESAEDMPRLGAIREGPATGLGSFLRR
TARSIMDLPWQIIQISETRQAGLFRLWAIIGSDLHCIKLSIPRVFYVNQRVAKAEDGPSY
RKVNRALPRSNIVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQL
GCVCVVNKQLARQLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHTQGHKALFG
VFIPSQRRASVFVLDTVRSNQMPGLSALYSAEHSLLLDKVGPNLLPPPKHTFEVRAETNL
KTICRAIQRFLLAYKEERRGPTLIAIQSSWELCRLTSEIPVLEEFPLVPVRVADKISYAV
LDWQRHGARRMIRHYLNLDICLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQRHN
HLLWLSPTSRPDLGGKEADDNRLVMEFDDRATVEINNSGCYSTVCVELDIQNLAVNTILQ
SHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALASYDETALCSSTFRILKSMVVG
WVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGS
SVIYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSN
YGGIKGKVPSSIHCGQVREQDSQTREETEDEEDNEKDEEEEEDMGQSEVEDLLENNWNIL
QFLPQAASCQSYFLMIVSAYIVAVYQSMKDELRHSAPGSTPVKRKGASQFSQEAEGAAGA
LPGMITFSQDYVANELTQTFFTITQKIQKKVTGSRNTAEPSEMFPVLPGSHLLLNNPALE
FIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNF
CRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLK
CRGMKETHMPVYCGCAGDFVLTIHTEVFMEQIRIFQNIAKYYNMSYLQEAIEWLLQTSPV
SNF
NT seq 6852 nt   +upstreamnt  +downstreamnt
atggtgctgaggaacagtggacggaggcatcccgagccgggcgcggacagcgaaggcagc
cgggatgatggtccctcctcttcagtctcagcactcaagcgtctggaacggagccagtgg
acggataagatggacttacggtttggttttgaaaggttgaaagagcctggagaaaggact
ggctggcttatcaacatgcaccctacagagattttagatgaagacaaacgcttagtcagt
gcagtggattactacttcattcaagatgatggaagcagatttaaggtggccttgccctac
aagccatatttctacattgcagctagaaagggttgtgatcgagaagtttcatcttttcta
tccaagaagtttcagggtaaaattgcaaagttagagaatgtgcccaaagaagacctggac
ttgccaaaccacttggtgggcttgaagcggagttacatcaagctgtccttccacactgtg
gaggatcttgtcaaagtgagaaaggagatctctcctgctgtgaagaagaaccgagagcag
gaccatgctagtgacgagtacacaacaatgctctccagtattctgcaaggaggcagtcta
attactgatgaggaggaaacctctaagaagatagctgaccaattggacaacatagtggac
atgcgggagtatgatgttccctaccacattcgcctctccattgacctcagaatccatgtg
gcccactggtacaatgttagatttcgaggaaatgcttttcctgtggaaattgcccgacga
gatgatctcgtcgaacgacctgatcctgtggttttggcatttgacattgagacaaccaaa
ctacctctcaaattccctgatgctgagacagatcagattatgatgatctcctatatgatt
gatggccagggctacctcatcactaacagggagattgtttcagaagacattgaagatttt
gagttcacccccaagccagaatatgaagggcctttctgtgtcttcaatgaacctgatgag
gtccatctgatccagagatggtttgagcatatccaggagaccaaacctaccattatggtc
acctacaatggggatttttttgactggccgtttgtggaggccagggcagcaattcatggc
ctaagcatgtaccaggagataggcttccagaaggatagccagggggaatataaggcacca
cagtgcatccacatggactgcctcaggtgggtgaagagggacagttaccttcctgtgggc
agtcataatctcaaggcagctgccaaagccaaacttggctatgaccctgtggagctggac
cctgaggacatgtgccgtatggccactgaacagccccagactctggccacttactcagtg
tcagatgctgttgctacttattacctgtacatgaaatatgtgcaccccttcatattcgcc
ctctgcaccattattcccatggaacctgatgaggtgctgcggaagggctctggaacattg
tgcgaagccttgctgatggtgcaagccttccatgccaacattatctttcccaataagcaa
gagcaggagttcaacaagctgacagatgatggccacgtgctagatgctgagacctacgtt
gggggccatgtggaggccctagagtctggtgtcttccgaagtgatatcccctgccggttt
aggatgaatcctgcagcctttgatttcctgctgcagcgagttgagaagactatgcgccat
gccattgaagaagaagagaaggtgcctgtggaacaagccaccaacttccaagaggtgtgt
gagcagattaagaccaaactcacctccctaaaagatgttcctaacagaattgaatgtcct
ctaatctaccatctagatgtgggggccatgtatcctaacataatcctcaccaaccgcctg
cagccttctgccatagtggatgaggccacctgtgctgcctgtgacttcaataagcctgga
gcaacttgtcagaggaaaatggcctggcaatggaggggagaattcatgccagccagtcgt
agtgagtaccatcgaatccagcatcagctagagtcggagaagttcccccctttgttccca
gaggggccagcaagggcctttcatgagctgtcccgtgaagaacaggctaaatacgagaaa
cggaggctggcagattattgccggaaagcctataagaagatccatatgaccaaggtagaa
gagcgcctgactaccatctgccagcgggaaaactcattttatgtggacacagtgcgggcc
ttcagagacaggcgctatgaattcaaaggactgcacaaggtgtggaagaagaagctctcg
gcggctgtagaggtgggcgatgcatcagaggtgaagcgctgcaagaacatggagatcctt
tatgattcgctgcagctggctcacaaatgcatcctgaactcattctacggctatgttatg
cgcaaaggagctcgctggtactccatggagatggctggtatcgtctgctttacaggagcc
aacatcatcacccaggcaagagagctgattgagcagatcgggaggcctttagaactggac
acggacggaatatggtgcgttctacccaatagctttcctgaaaattttgtcatcaagaca
accaatgtgaaaaaacccaaactgaccatctcctatcctggtgccatgttgaacatcatg
gtcaaggaaggctttaccaaccaccagtaccaggaactaacagagccttcgtctctcacc
tatgtcacccgctctgagaacagcatcttttttgaagttgatggaccataccttgctatg
atccttccagcctccaaggaagaaggcaagaagctgaagaaaagatatgctgtattcaat
gaagatggctccttggctgaactgaaaggttttgaggtgaaacgccgaggggagttgcag
ttgattaaaatcttccagtcctcagtgtttgaggccttcctcaagggcagcacactagag
gaggtgtatgcctctgtggccaaagtggctgactactggctagatgtgctctatagcaag
gctgctaatatgcccgattctgaattattcgaactgatttctgagaaccgctccatgtca
cggaagctagaagattatggggagcagaagtctacgtccatcagcacagcaaagcgcctg
gctgagttcctgggagaccagatggtcaaagatgctggactgagctgccgctacattatc
tcccgaaagccagagggatctcctgtcactgagagggccattccacttgccattttccaa
gcagagcctacagtgaggaaacattttctccggaaatggttaaagagttcatcacttcaa
gactttgatattcggacaattctggactgggactactacatagagcggctggggagtgcc
atccagaaaatcatcaccatccctgcagctctacagcaggtgaagaacccagttccacgt
gtcaaacatccagactggctgcacaaaaagctactagagaagaatgatatctacaaacag
aagaagatcagtgagctctttgtgcttgaaggaaagagacagattgtgatggcccaggct
tcagaaaacagtctgagtctctgcactccagacatggaggactttggactcacaaagcca
tatcactctacagttccagttgctactaagaggaagcgagtctgggagagccaaaaggag
tctcaggatattacactaactgtgccctggcaagaggtcttagggcagcctccctccctt
ggaaccacacaggaagagtggttggtctggctccagttccacaagaaaaagtggcagctg
caggctcaacagcgcctagcccgcaggaagaaacagcgcttagagtcagcagaagatatg
ccaaggcttggggctatccgagaggggcctgccacaggactggggagctttctgcgacgg
accgcccgcagcatcatggacctcccctggcagatcatacagatcagtgagaccagacag
gctggtctgttccggctgtgggctatcattggcagcgacttgcactgcatcaagctgagt
atccctcgagtattctatgtaaaccagcgggtagccaaagcagaggatgggccttcgtat
cgaaaggtgaatcgggctcttcctcgttccaacatcgtctacaatctctatgagtactca
gtaccagaggacatgtaccaagaacacatcaacgagatcaacactgagttgtcagcacca
gacattgagggcgtgtatgagactcaggtcccattgttattccgggccctggtgcagctg
ggctgtgtgtgtgtggtcaacaaacagctggcaaggcaactttcaggctgggaagctgaa
acctttgccctcgagcaccttgaaatgcgttctctggcccagttcagctacttggaacca
gggagtatccgccacatctacctgtaccatcacacacagggccacaaggcactctttggg
gtctttatcccctcacagcgaagagcatctgtgtttgtgttggatactgtgcgcagcaac
caaatgccagggctcagtgccctatactcagcagaacacagcctgctgctggacaaggtg
ggccccaacctcctgcctcccccaaaacacacctttgaagttcgtgctgaaaccaacctg
aagaccatctgcagagccatccaacgcttcctgcttgcctacaaggaagagcgccggggg
cccacgctcatcgctatccagtctagctgggaactgtgtaggctgaccagtgagattcca
gtcttagaggagttcccactagtgcctgtccgagtggctgacaagatcagctatgcagtc
ctggactggcagcgccacggagctcgccgaatgatccggcactacctcaatttagacatt
tgcctttcacaggcctttgagatgagcaggtacttccacatccccgttggaaacctgcca
gaagacatctccacctttggctctgacctcttttttgcacgccatctccagcgccataac
cacctactttggttgtcccctacctctcggcctgacctgggtgggaaggaagctgatgac
aaccgccttgtcatggagtttgatgaccgagccactgtggagatcaataattccggctgt
tactctactgtgtgcgtggagctggacattcaaaacctggcagtcaacaccatcctccag
tcccaccatgtcaatgacatggagggggctggcagcatgggcatcagcttcgatgtgatc
cagcaggcctccctagaggacatggttacaggcaatcaagctgccagtgccctggccagc
tacgatgagacagccctctgctccagtacgttcaggatcctgaagagcatggtggttggc
tgggtaaaggaaatcacacagtaccacaacatctatgctgacaaccaggtgatgcacttc
taccgctggctccagtcgccgtgctctctgctccacgacccagcccttcaccggacactg
cacaatatgatgaagaagctcttcctgcagctcattgctgagttcaagcgcctggggtca
tcggtcatctatgccaacttcaatcgcatcatcctctgtacaaagaagcgccggatagag
gatgcccttgcctatgtggaatatatcaccaacagcatccattctaaagagatctttcat
tccctgaccatctctttctctcgatgctgggaattccttctctggatggatccatccaac
tatggtggaatcaaaggaaaagtcccatccagtattcactgtggacaagtaagggagcaa
gactcccagacaagggaggaaactgaggatgaggaggacaatgaaaaggatgaggaggaa
gaggaggacatggggcaatctgaggttgaggacttactggagaacaactggaacattcta
cagttcttgccacaggcagcctcttgccagagctacttccttatgatcgtttcagcatac
atcgtggctgtgtaccaaagcatgaaggatgagttgagacacagtgccccaggcagtacc
cctgtgaagaggaagggggccagccagttctcccaggaggctgaaggggcagccggggcc
cttcctggaatgatcactttctctcaagattatgtggcaaatgagctcactcagaccttc
ttcaccattactcagaaaattcagaagaaagtcacaggctctcggaacaccgctgagccc
tcagagatgttccctgtcctccctggttcacatttgctgctcaataaccctgctctggag
ttcatcaaatacgtgtgcaaggtactatctctggatacaaacatcacaaatcaggtgaat
aagctaaacagagacctgcttcgcctggtagacgttggtgaattctctgaggaggcccag
ttcagagacccctgccactcctacgtgctccctgaggtaatctgccacagctgtaatttc
tgccgagacctggacctatgcaaagattcttctttctctcaggacggagccatcctgcct
cagtggctttgctccaattgtcaggccccctacgactcatctgccattgagtcagccttg
gtggaagccctgcagaggaaactgatggccttcacacttcaggacctggtgtgcctcaag
tgccgtggtatgaaagagacccatatgcctgtgtactgcggctgcgcaggggactttgtt
ctcaccatccatactgaggtcttcatggaacagattagaatcttccagaacattgccaag
tactacaacatgtcatatctccaagaggccatagaatggctgctacagacaagccctgta
tcaaacttttag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (13)   
   RefSeq(nuc) (13)   
Protein domain (6)   
   Pfam (6)   
All databases (40)   

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