KEGG   Rattus norvegicus (rat): 304883
Entry
304883            CDS       T01003                                 
Symbol
Abl2
Name
(RefSeq) tyrosine-protein kinase ABL2
  KO
K08887  abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    304883 (Abl2)
   04014 Ras signaling pathway
    304883 (Abl2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    304883 (Abl2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    304883 (Abl2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    304883 (Abl2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     304883 (Abl2)
Protein kinases [BR:rno01001]
 Non-receptor tyrosine kinases
  ABL family
   304883 (Abl2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase F_actin_bind SH2 SH3_1 SH3_2 SH3_9 SH3_3 Haspin_kinase SH3_6 ABC1 RGS12_us1 Kinase-like
Other DBs
NCBI-GeneID: 304883
NCBI-ProteinID: NP_001382059
RGD: 1590898
Ensembl: ENSRNOG00000004305
Position
13:71223902..71319770
AA seq 1182 aa
MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPVGRTADAGFNVFTQHDHFASCVE
DGFEGDKTGGSSPEVLHRPFGCDAESQALNEAIRWSSKENLLGATESDPNLFVALYDFVA
SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR
SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFST
LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG
EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV
TEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN
HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT
YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE
TMFHDSSISEEVAEELGRTASSSSVVPYLPRLPLLPSKTRTLKKQGENKENLDGGLDASE
ILASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKK
RNAPMPPKRSSSFREMENQPHKKYELTGNFSPVASLQHADGFSFTPGQQESNLVPAKCYG
GSFAQRNLCGDDDSGGGGGSGTAAGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPF
PRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSE
EGAAPARERPKAKLLPRGATALALRAPDPAITESDCPGVGVAGVAAAPKGKERNGGTRLG
VAGVPEDAEQPGWSSPAKAVAVLPTTHNHKVPVLISPTLKHTAADVQLIGTDSQGNKFKL
LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAGQHTPDTQD
GGKKAAPGPVPSSGKPGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS
ADKISKAALLECAGLLSSAITEPVPHSQLVDTGHQLLHYCSGYVDCIPHTRNKFAFREAV
SKLELSLQELQVSSTAAGVPGTNPVLNNLLSCVQEISDVVQR
NT seq 3549 nt   +upstreamnt  +downstreamnt
atggggcagcaggtgggccgcgtcggggaggctcccgggctccagcagccacagccgcgc
gggatccggggcagcagcgcagccaggccctccggccgcaggcgggacccggtggggcgt
accgcagacgccggcttcaacgtcttcacccagcacgatcactttgccagctgtgtggag
gatggatttgagggagacaagactggaggcagtagtccagaagttttgcaccgccccttt
ggttgtgacgctgaatctcaggcactgaatgaagctatcaggtggagctccaaggagaac
ttgctgggcgccactgagagcgaccctaatctctttgttgcactttatgactttgtggca
agtggcgataacacactcagcatcaccaaaggtgaaaagctacgagtccttggttacaac
caaaatggtgaatggagtgaagttcgctccaagaatgggcagggttgggtgcccagcaac
tacatcactccagtcaacagcctggagaaacattcctggtaccatgggcctgtgtcccgc
agtgcagcggagtatctcctcagcagccttatcaatggcagtttcctggtgcgagagagt
gagagcagccctgggcagctgtccatctctctcagatatgagggacgtgtgtatcactac
aggatcaataccaccacagacagcaaggtgtacgtgactgccgagagccgcttcagcacc
ttagcagagcttgttcaccaccactccacagtcgctgatgggctagtgaccacgctacat
tacccagcacccaagtgcaacaagccaaccgtctacggtgtgtctcctatccacgacaag
tgggagatggagcgcacagatatcaccatgaagcacaagcttgggggcggccagtatgga
gaggtttacgttggcgtctggaagaaatacagccttacagttgctgtgaaaacactgaag
gaagataccatggaggtagaggagttcctgaaggaagctgcagtgatgaaggaaatcaag
catcctaatttagtacagctgttaggtgtgtgcaccctggagccgccattctacattgtg
actgaatacatgccgtacgggaatctgctcgattacctccgggagtgcagccgtgaggag
gtgactgcagtggtgctgctttacatggccactcagatctcctctgccatggagtacttg
gagaagaagaacttcatccacagagatcttgctgcacggaactgcctggtgggggagaac
catgtggtgaaagtggctgactttggtctaagtagactgatgactggagacacctacacc
gctcatgctggagccaaatttcctattaaatggacagcgcctgagagtctggcctacaat
accttttcaattaaatctgacgtttgggcttttggagtactgttgtgggaaattgctacg
tatggaatgtcaccatatccaggtattgacctatctcaagtctatgacctactggaaaaa
ggatatcgaatggagcagcctgagggatgcccccctaaagtgtatgaacttatgagagca
tgctggaagtggagccctgcggacaggccctcttttgctgaaacccatcaagcttttgaa
accatgttccatgactccagcatctctgaagaggtagctgaggagcttgggagaactgcc
tcctcctcatctgtagttccatacctgcctcgactgccactacttccttccaagacaagg
accctgaagaagcagggggagaacaaagagaacctagatgggggccttgatgcctccgag
atcctggcctccagctcagcaccagcagggttcattagaagcacccaggcctccagtggg
tccccagctctgcctcgaaagcaaagagataagtcacccagcagcctcttagaagatgcc
aaagagacatgcttcaccagggacaggaagggaggcttcttcagctccttcatgaaaaaa
agaaatgcccccatgccccctaagcgcagcagctcttttcgagaaatggagaatcagccc
cacaagaaatatgaactcacgggtaacttctcacctgttgcttctctgcagcatgctgat
gggttctctttcactcccggccagcaagagtcgaatctggtgccagccaagtgctatggg
gggagctttgcacagaggaacctctgtggtgatgatgacagtggtgggggtgggggtagt
ggcactgctgcgggtgggtggtctggtatcacaggcttctttacacctcgcttaatcaaa
aagacactgggcttgcgagcaggtaaaccgacagccagtgatgacacttccaagcctttt
ccaaggtcaaactctacatcttccatgtcctcagggctccccgagcaggataggatggca
atgacccttcccaggaactgccagaggtccaaactccagctggaaaggacagtgtccacc
tcttctcaaccagaagagaatgtggacagggctaatgacatgcttccaaaaaaatcagag
gaaggtgctgctccagccagggagagaccaaaagccaaactattgcccagaggagccacg
gctcttgccctgagagcccctgatccagccatcactgagagtgactgtccaggggtaggg
gtggctggagtggcagctgcccccaaaggcaaggagaggaatggtgggacgcggcttgga
gtcgctggagtcccagaggacgcagagcagccaggctggtcttctccagccaaggctgta
gctgtcctcccaaccactcacaaccacaaagtgccagtccttatctcacccactctgaaa
cacactgcagctgatgtgcagctcattggcacagactctcaggggaacaaattcaagctc
ttatctgagcatcaggtcacatcctctggagacaaggaccgaccccgacgggtaaaacca
aagtgtgccccacccccgccaccagtgatgagactactgcagcatccgtccacatgctca
gaccccgaggaagagccaactgccccccctgcaggacagcacactccagacacccaggac
ggaggaaaaaaggcagctccagggccagtgcccagtagtgggaaacctgggaggccagtg
atgcctccacctcaagtgcctttgcccacatcttccatctcgccagccaaaatggccaat
ggcacagcaggtactaaggtggccctgaggaaaaccaaacaggcagctgagaaaatctca
gctgacaaaatcagcaaagcggccctgctggagtgtgccggcctactgtccagtgcaatc
acagaacctgtgccccatagccagctggtggacactgggcaccagctactccactactgc
tcagggtatgtggactgcatcccccacactcgcaacaaatttgccttccgagaggctgtg
agcaaactggaacttagcttacaggagctgcaggtgtcttccacagctgctggtgtgcct
gggacaaaccctgtccttaataacttattgtcatgtgtacaggaaattagtgatgtggtg
cagaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (15)   
   UniProt (2)   
   RefSeq(pep) (13)   
DNA sequence (14)   
   RefSeq(nuc) (14)   
Protein domain (13)   
   Pfam (13)   
All databases (57)   

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