KEGG   Rattus norvegicus (rat): 305509
Entry
305509            CDS       T01003                                 
Symbol
Adcy1
Name
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno01100  Metabolic pathways
rno01522  Endocrine resistance
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04114  Oocyte meiosis
rno04211  Longevity regulating pathway
rno04213  Longevity regulating pathway - multiple species
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04371  Apelin signaling pathway
rno04540  Gap junction
rno04611  Platelet activation
rno04713  Circadian entrainment
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04727  GABAergic synapse
rno04750  Inflammatory mediator regulation of TRP channels
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04913  Ovarian steroidogenesis
rno04914  Progesterone-mediated oocyte maturation
rno04915  Estrogen signaling pathway
rno04916  Melanogenesis
rno04918  Thyroid hormone synthesis
rno04921  Oxytocin signaling pathway
rno04923  Regulation of lipolysis in adipocytes
rno04925  Aldosterone synthesis and secretion
rno04926  Relaxin signaling pathway
rno04927  Cortisol synthesis and secretion
rno04928  Parathyroid hormone synthesis, secretion and action
rno04934  Cushing syndrome
rno04935  Growth hormone synthesis, secretion and action
rno04970  Salivary secretion
rno04971  Gastric acid secretion
rno04972  Pancreatic secretion
rno04976  Bile secretion
rno05032  Morphine addiction
rno05142  Chagas disease
rno05146  Amoebiasis
rno05163  Human cytomegalovirus infection
rno05166  Human T-cell leukemia virus 1 infection
rno05200  Pathways in cancer
rno05207  Chemical carcinogenesis - receptor activation
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    305509 (Adcy1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    305509 (Adcy1)
   04371 Apelin signaling pathway
    305509 (Adcy1)
   04020 Calcium signaling pathway
    305509 (Adcy1)
   04072 Phospholipase D signaling pathway
    305509 (Adcy1)
   04024 cAMP signaling pathway
    305509 (Adcy1)
   04022 cGMP-PKG signaling pathway
    305509 (Adcy1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    305509 (Adcy1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    305509 (Adcy1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    305509 (Adcy1)
   04062 Chemokine signaling pathway
    305509 (Adcy1)
  09152 Endocrine system
   04911 Insulin secretion
    305509 (Adcy1)
   04923 Regulation of lipolysis in adipocytes
    305509 (Adcy1)
   04912 GnRH signaling pathway
    305509 (Adcy1)
   04913 Ovarian steroidogenesis
    305509 (Adcy1)
   04915 Estrogen signaling pathway
    305509 (Adcy1)
   04914 Progesterone-mediated oocyte maturation
    305509 (Adcy1)
   04921 Oxytocin signaling pathway
    305509 (Adcy1)
   04926 Relaxin signaling pathway
    305509 (Adcy1)
   04935 Growth hormone synthesis, secretion and action
    305509 (Adcy1)
   04918 Thyroid hormone synthesis
    305509 (Adcy1)
   04928 Parathyroid hormone synthesis, secretion and action
    305509 (Adcy1)
   04916 Melanogenesis
    305509 (Adcy1)
   04925 Aldosterone synthesis and secretion
    305509 (Adcy1)
   04927 Cortisol synthesis and secretion
    305509 (Adcy1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    305509 (Adcy1)
   04270 Vascular smooth muscle contraction
    305509 (Adcy1)
  09154 Digestive system
   04970 Salivary secretion
    305509 (Adcy1)
   04971 Gastric acid secretion
    305509 (Adcy1)
   04972 Pancreatic secretion
    305509 (Adcy1)
   04976 Bile secretion
    305509 (Adcy1)
  09156 Nervous system
   04724 Glutamatergic synapse
    305509 (Adcy1)
   04727 GABAergic synapse
    305509 (Adcy1)
   04725 Cholinergic synapse
    305509 (Adcy1)
   04720 Long-term potentiation
    305509 (Adcy1)
   04723 Retrograde endocannabinoid signaling
    305509 (Adcy1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    305509 (Adcy1)
  09149 Aging
   04211 Longevity regulating pathway
    305509 (Adcy1)
   04213 Longevity regulating pathway - multiple species
    305509 (Adcy1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    305509 (Adcy1)
   04714 Thermogenesis
    305509 (Adcy1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    305509 (Adcy1)
   05207 Chemical carcinogenesis - receptor activation
    305509 (Adcy1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    305509 (Adcy1)
   05163 Human cytomegalovirus infection
    305509 (Adcy1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    305509 (Adcy1)
   05142 Chagas disease
    305509 (Adcy1)
  09165 Substance dependence
   05032 Morphine addiction
    305509 (Adcy1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    305509 (Adcy1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    305509 (Adcy1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    305509 (Adcy1)
Enzymes [BR:rno01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     305509 (Adcy1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom DUF6594 HNOBA
Other DBs
NCBI-GeneID: 305509
NCBI-ProteinID: NP_001100709
RGD: 1309318
Ensembl: ENSRNOG00000059479
UniProt: A6KJ71
Position
14:86125119..86234459
AA seq 967 aa
MGSAVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVPAKRPRLWRT
LGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPR
NVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFG
KFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDL
NMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYE
VEPGHGHERNTFLRTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMH
CRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLL
EARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILATLFGLIYLLVIPQ
SVAVLLLLVFSICFLVACTLYLHITRVQCFPGCLTIQIRTALCVFIVVLIYSVAQGCVVS
CLPWAWSSHSNSSLVVLAAGGRRTVLPALPCESAHHGLLCCLVGTLPLAIFLRVSSLPKM
ILLSGLTTSYILVLELSGYTKVGGGALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDY
LWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFAS
IPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLA
PTAGTRAKKSISSHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARR
PQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLNRCSYQFVCRGKVSVKGKGEMLTYF
LEGRTDGSSSHSRSLRLERRMFPYGRGGGGQARRPPLCPAAGPPIKPGLSPAPTSQYLSS
TAAGKEA
NT seq 2904 nt   +upstreamnt  +downstreamnt
atgggctcggcggttgccgaacagggggtttggcaactccttttggtcaccttcgtgtcc
tatgccttgctgcccgtgcgcagcctactggccatcggcttcgggctcgtggtggctgcc
tcgcacttactggtcacagccgccttggtccctgccaagcgcccacgtctctggaggacg
cttggtgccaatgccctgctcttctttggtgtgaacatgtatggcgtcttcgtgcggatc
ttgactgagcgctcccagaggaaggccttcctgcaggctcgaaactgcattgaggaccgg
ctgcggctggaagatgagaatgagaaacaggagcggttgctcatgagcctcttgccccgg
aatgtcgccatggagatgaaggaagacttcctgaagccccctgagaggatatttcacaag
atttacatccagaggcacgacaatgtgagcatcctgtttgcagacatcgtgggtttcaca
ggtctggcgtcccagtgcacggcccaggagctggtgaaactgctcaatgaactctttggc
aagttcgatgagttagccacggaaaaccactgtcgccgaatcaagatccttggagactgc
tactactgtgtgtctggcctcacccagcccaagacggatcacgcccactgctgtgtggag
atgggacttgacatgatcgataccatcacatccgtggctgaggctactgaagtagacctg
aacatgcgtgtgggcctacacactggcagggtcctctgtggtgtcctgggcctacgcaag
tggcagtacgacgtatggtccaacgacgtcaccctggccaatgtcatggaggctgctggc
ttaccagggaaggtccacatcacgaagacaacccttgcgtgcttgaacggggactacgag
gtggagccgggccacggccatgagaggaacacctttctgagaactcacaacatcgagacc
ttctttattgtgccatcccatcggaggaagatatttccaggtttgattctctcggatatc
aaaccagccaagaggatgaagttcaagaccgtctgctacctgctggtgcagctcatgcat
tgccggaaaatgttcaaggctgagatccccttctccaacgtaatgacctgtgaggatgat
gacaagcgaagggcattgagaacggcctcggagaagctcagaaaccgttcgtcattctct
accaacgtggtctacaccactccgggtacgcgtgtcaacaggtacatcagccgccttctt
gaagcccgccagacagagctggagatggccgacctgaacttctttaccctcaagtacaag
catgttgaacgggaacaaaaataccaccagcttcaagatgagtacttcaccagcgccgtt
gtcctcgccctcatcctggctaccttatttgggcttatctaccttctggtaatcccacag
agcgtggctgtcctgctgctgctggtgttttctatctgcttcttggtggcctgtaccctg
tacctgcacatcacgagggtccagtgttttccagggtgcctgaccatccagatccgcacc
gctctgtgtgtgttcatcgtggtcttaatctactcagtagctcaaggatgtgtggtgagc
tgtctgccttgggcctggagctctcactccaacagctccctagtggtcctcgcagctggt
ggccggcgcactgtgctgcctgccctgccctgtgagtctgcacaccatggcctgctctgc
tgcctggtgggcaccctcccactagccatattcctgcgggtgtcctccttgccaaagatg
atcctgctgtctgggctgacgacttcctacatccttgtcctggagctcagtggatacacc
aaggttgggggcggtgccctctctgggcgcagctatgagcccatcatggctatcctgctg
ttctcatgcacgctggccctgcacgccaggcaggtggacgtcaggctacggctggactac
ctctgggcagcacaggcggaggaggaacgggacgacatggagagggtaaagctggacaac
aagaggatcctcttcaacctcctgccagcgcacgtcgcacagcacttcctcatgtccaat
ccccggaacatggatctctattaccagtcctactcccaggtgggcgtcatgttcgcctcc
atccccaacttcaacgacttctacatagaactggatggcaacaacatgggcgttgagtgt
ctgcggctcctcaatgagatcattgctgactttgatgagctcatggacaaggacttctac
aaggacctggagaagatcaagaccattgggagtacctatatggctgccgtggggctggcg
cccacagcaggaaccagggctaagaagtccatctcttcccatctgagcacgctggcagac
tttgccatcgacatgtttgatgtcctggatgagatcaactaccagtcctacaacgacttc
gttctccgagtcggcatcaacgttggccccgtggtcgctggagtgatcggtgctcgcagg
ccccagtacgacatctggggaaacacagtcaatgtggccagtcggatggatagcactggg
gtccagggaagaattcaggtgactgaggaagtccaccgactgctgaacaggtgctcatac
cagtttgtgtgcagaggcaaagtcagcgtcaagggcaagggagagatgctaacgtacttt
ctagaaggcaggactgatgggagcagttcccacagcaggtcccttcgcttggagcgaagg
atgtttccttatgggagaggcggcggaggccaggccaggcggcccccattgtgtcctgca
gctggacccccaatcaaaccggggctctctccagcccccactagccagtacctgtcatcc
acagcagcagggaaggaagcctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (52)   
   KEGG PATHWAY (52)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (77)   

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