KEGG   Rattus norvegicus (rat): 306103
Entry
306103            CDS       T01003                                 
Symbol
Dis3
Name
(RefSeq) exosome complex exonuclease RRP44
  KO
K12585  exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    306103 (Dis3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    306103 (Dis3)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Exosome cofactors
     306103 (Dis3)
SSDB
Motif
Pfam: RNB OB_Dis3 PIN_4 Rrp44_CSD1 Rrp44_S1 CSD2 Toxin_R_bind_C
Other DBs
NCBI-GeneID: 306103
NCBI-ProteinID: NP_001120955
RGD: 1304646
Ensembl: ENSRNOG00000009125
UniProt: B2RYL7
Position
15:complement(82231922..82258299)
AA seq 957 aa
MLKSKTFLKKTRAGGVVKIVREHYLRDDIGCGTPACSACGAAHAGPALELQPRDQASSLC
PWPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPIYKRIRDVTNNQEKHF
YTFTNEHHKETYIEQEQGENANDRNDRAIRVAAKWYNEHLKMSAENQLQVILITNDKKNK
EKAAEEGIPAFTCEEYVKSLTANPELIDRLACLSDEMNEIESGKIIFSEHLPLSKLQQGI
KSGSYLQGTFRASRENYLEATVWIHGDKEDEKEILIQGLKHLNRAIHEDIVAVELLPKSQ
WVAPSSVVLHDEGQNEDDVEKDEERELLLKTAVSEKMLRPTGRVVGIIKRNWRPYCGMLS
KSDIKESRRHLFTPADKRIPRIRIETRQASALEGRRIIVAIDGWPRNSRYPNGHFVKNLG
DVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEEDMKNREDLRHLCVCSVDPP
GCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVP
ELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRIDSAA
MNDDITTSLRGLNKLAKILKRGRIEKGALTLSSPEIRFHMDSETHDPIDLQTKELRETNS
MVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEVLVKAAKSKNLEIRTDTAKSL
ADSLDRAECPDFPYLNTLLRILATRCMMQAVYFCSGMDSDFHHYGLASPIYTHFTSPIRR
YADIIVHRLLAVAIGADCTYPELTDKHKLSDICKNLNFRHKMAQYAQRASVAFHTQLFFK
SKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPKPRLTYDDEIPSLRIEGTVF
HVFDKVKVKITLDSSNLQHQKIRMALVEPQIPGINMPPDVSDMDLNGPGGKKRKLEK
NT seq 2874 nt   +upstreamnt  +downstreamnt
atgctcaagtccaaaacattcttaaagaagacccgcgcgggcggcgtggtgaagatcgtg
cgcgagcactacctgcgggatgacatcggctgcggcacgccggcttgctcggcctgtggc
gcggcgcacgcgggcccggccctggagctgcagccccgggaccaggcgagcagcctctgc
ccatggccgcactacctcctgccggacaccaatgtgctgctgcaccagattgatgttctt
gaggaccctgctatcaggaacgtaattgtgcttcagacagtcctgcaggaagtgagaaac
cggagtgcccccatatataagcgaatcagggatgtgacgaataaccaggagaagcatttc
tatacgttcactaacgagcaccataaagaaacctacatagagcaagaacagggggagaat
gccaatgacagaaatgacagagccattcgagtagcagcaaagtggtacaatgaacatcta
aagatgtcagcagaaaatcagctacaagttatccttataacaaacgacaagaagaacaaa
gaaaaggctgcagaagaaggaataccagctttcacatgtgaagaatatgtaaagagcctg
actgctaaccctgaacttatagatcgtcttgcttgtttgtctgatgagatgaatgaaata
gaaagtgggaaaataatattttcagagcatcttcctttaagcaagctccaacaaggcata
aaatctggttcataccttcaaggaacattcagagctagcagggaaaattacttagaagct
acagtgtggattcatggagacaaagaagatgaaaaagagatacttatacaaggacttaaa
catctaaacagagctattcatgaagatattgtggctgtggaactattgcccaagagtcag
tgggtggcaccatcttctgtggttttacatgatgaaggtcaaaatgaagatgatgtggag
aaagatgaggagagagaactcctgcttaagactgctgtaagtgaaaaaatgttgaggcct
acaggtagagttgtggggataataaagaggaattggagaccgtactgtggcatgctttcc
aagtctgatattaaggagtcaagaagacatctctttacacctgctgataagagaattcca
cgaattcggatagaaaccagacaggcttctgcattagaaggacggagaattattgtcgct
attgatggttggcccagaaattctagatatccaaatggacactttgtaaaaaatttaggt
gatgttggagagaaagagacggaaacggaagttttgctgcttgagcatgacgttcctcat
cagcccttttcccaggctgttcttagcttcctgccgaagatgccctggagcattactgag
gaggacatgaaaaaccgagaagatctgagacatctgtgtgtttgcagtgtggatcctcca
ggatgtactgacatagatgatgccctgcactgcagagaactcagcaatggaaacttggag
gttggtgttcatattgcggatgttagccattttatcaggccaggaaatgcattggatcaa
gaatcagcaagaagaggaacaactgtttatctttgtgaaaagaggattgacatggtccca
gagctgctcagctccaacctctgttccttaagatccaacgtggacaggttggcattttcc
tgtatttgggaaatgaatcataatgctgaaatattaaaaacgagatttaccaaaagtgtc
attaattcaaaggcttctcttacatatgctgaagcacagatgagaattgattcagccgct
atgaatgatgacattaccactagtctccgtggactgaataaactagctaaaattctaaaa
aggggaaggattgaaaagggggctttgacactctcttctccagaaattcgatttcacatg
gacagtgaaactcacgacccaattgacctgcagaccaaggagctgagagaaacaaattcc
atggtggaagaatttatgttactcgctaatatttctgttgcaaaaaaaattcatgaagag
ttttctgaacatgctttgcttcgaaaacatccagccccacctccctccaattatgaagtt
cttgttaaggccgctaagtccaagaatttggaaattcggactgatacagccaaatctttg
gctgactctttggaccgggctgaatgtcctgatttcccatacctgaatactctgttaagg
atattggccactcgctgtatgatgcaagctgtctacttctgttctgggatggatagtgac
tttcatcactatggcttagcctccccaatatacacacatttcacttctcctatcagaaga
tatgcagacataattgttcatcggctattagctgtggcgattggggctgattgtacttat
ccagagttgacggacaaacacaagctttcagatatatgtaaaaacctcaatttccggcat
aaaatggctcagtatgcccagcgtgcgtcagtagcttttcatacacagttgtttttcaaa
agcaaaggaatagtaagcgaagaagcctatattctctttgtaagaaaaaatgcaattgta
gtgttaattccaaagtatggcttagaaggtacagttttttttgaagaaaaagataaacca
aagccacgccttacttatgatgatgagataccttcactcagaatagaaggtacagtgttc
catgtgtttgataaagttaaagtgaaaatcacattagattcatcaaatcttcaacaccag
aaaatccgcatggcccttgtagaaccacagataccaggaataaatatgcctcctgatgtt
tcagacatggatcttaatggaccagggggaaagaagaggaaacttgaaaagtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (34)   

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