KEGG   Rattus norvegicus (rat): 306811
Entry
306811            CDS       T01003                                 
Symbol
Wnk2
Name
(RefSeq) serine/threonine-protein kinase WNK2
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    306811 (Wnk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    306811 (Wnk2)
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    306811 (Wnk2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     306811 (Wnk2)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: Other
  Wnk family
   306811 (Wnk2)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     306811 (Wnk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 306811
NCBI-ProteinID: NP_001178485
RGD: 1307284
Ensembl: ENSRNOG00000016684
Position
17:15709648..15818874
AA seq 2063 aa
MDGDGGRRDAPGALMEAGRGTGSAGMAEPRARAARLGPQRFLRRSVVESDQEEPPGLEAA
ETPSAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAAPAAPPGSPSAPSDPGPERAG
TQEPSPDPTTASAAATPVPDGGPRQEEAPAPTQEDTGATEAKPEPGRARKDEPEEEEDDE
DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK
EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS
WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT
PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK
VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV
EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIDSGFFHESDVKIVAKSIRDRVALIQ
WRRERIWPALQSQEPKDTGSPDKARGLPAPLQVQVTYHAQSGQPGQPEPEEPEADQHLLP
PTLPASVTSLASDSTFDSGQGSTVYSDSQSSQHSMVLSSLVDTAPTPASCVCSPPVSEGP
GLTHSLPKLGAFQQPAAVPGLSVGPVPPPARPPLLQQHFPEPSMSFTPVLPPPSTPVPTG
PSQPAPPVQQPLPMAQPPTLPQVLAPQPMGTVQPVPSHLPPYLAPTSQVVAPAQLKPLQM
PQPPLQPLAQVPPQMPQMPVVPPITPLAGLDGLPQTLADLPAANVAPVPPPQYFSPAVIL
PSLTTPLPTSPALPLQAVKLPHPPGAPLAVPCQTIVPNAPAAIPLLAVAPQGVAALSIHP
AVAQIPAQIPAQPVYPAAFPGMVPGDVPPSPHHTVQSLRATPPQLASSVPPQSVQPSVVH
LPEQAAPSAASGTQVLLGHPPSYTTDVAAPVSAVSLPPAVLSPPLPDTLLPTVPELLPKL
PSSLAPTVVAASQSVPTQTSTLLPPTNPPLPTGPAVAGPCPAVQLTVEAAQEEQVSQDKP
PGPPQSCESLGGSDVTSGRDLSDNCEGTFGTGRLEGRAARKHHRRSTRARSRQERASRPR
LTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILPAERETFIE
QMKDVMDKAEDMLSEDTDADHGSDTGTSPPHLGTCGLTTGEENGQSQANAPVYQQNVLHT
GKRWFIICPVAEHPAADTSESSPPLPLSSLQPEASQDPAPYPDQLSLTDKPSFPAAQQLL
SQAGSSNPPGGASAPTAPSSPPVTSVMPAAPATSTVPESAAGTAMQAGGPGTHQGPASVH
ETLHPLAETHRAQGAAQPLSTGQGPCTPALEASHCSTGLGEPISTKEVSTQGGTLSASMP
EPSPPTGAVQSVPSQPPPPLPITVGTIGLAAPQLPSPPLGPTAPPPPPSALESDGEGPPP
RVGFVDNTIKSLDEKLRTLLYQEHVPTSSASAGTPLEANDRDFTLEPLRGDLPSALSDKT
PSLTQQSQPSLEKSETAPAGWALAPREQGASSSMTAESSSSNTLGCDSDTGQVASDSPTA
PSVPQDTSVSSVPTHMDPKDQNGSAPRETLVAPMQSCPGTFTEGSPAQLRGVRDSGSPHK
RPGQQDSSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEIPSSPEVKLAVRRV
QTASSIEVGVEEPASSDSGDECPRRRTQVQKQSSLPGSGGVASDFVKKATAFLHRSSRAG
SLGPETPSRAGVKVPTISITSFHSQSSYISSDNDSEFEDADIKKELRSLREKHLKEISEL
QSQQKQEIEALYRRLGKPLPPNVGFFHTAPPMGRRRKTSKSKLKAGKLLNPLVQQLKVVA
SSTGSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPTLHVQAQVNNSNNKKGTFTDDLHKL
VDEWTTKTVGAAQVKPTLNQLKQTQKLHDMEASGEARATSVPRGGVATSCLAPAPGPLSS
TAIPGVTPALPVPTPDPESEKPD
NT seq 6192 nt   +upstreamnt  +downstreamnt
atggacggcgatggcggccgccgagacgcccccggcgcgttgatggaggccgggcgcggc
acggggtcggcgggcatggcggagccgcgagcgagggcggcgcggctcgggccccagcgc
ttcctgcggcgcagcgtggtggagtcggaccaggaggagccgccgggcctggaggcggcc
gagacgccgagcgcgcagcccccacagcccctgcagcgcagggtgcttctactctgcaag
acgcgccgcctcatcgcggagcgcgcccggggccgccccgccgcgcccgcgcctgccgcg
cccgctgcgcctcctggctccccgagtgccccctcggaccctggcccggagcgagcgggc
acgcaggagcccagcccagatcccaccaccgcgtcagctgcagccaccccggtccccgac
ggcggcccgcggcaggaggaggcgcccgccccaacccaggaggacactggagctaccgag
gcaaagccggagcccgggcgcgcacgcaaggatgaacctgaggaggaggaggacgatgag
gacgacctcaaggctgtggctacctctttggacggccgcttcctcaagttcgacatcgag
ctgggccggggctccttcaagacggtctacaaggggctggacacggagacctgggtggag
gtagcatggtgtgaactgcaggaccggaagctcaccaaactcgaacggcagcggttcaaa
gaggaggcagagatgctgaaaggtctacagcaccccaacattgtgcgcttctatgacttc
tgggagtccagtgccaagggcaaacgatgtattgtgctggtgacggagctgatgacctca
gggacattgaagacgtacctgaagcggttcaaggtgatgaagcccaaggtactgagaagc
tggtgccggcagatcctgaagggcctgttgtttctgcacacaaggactccccccatcatc
caccgagacctcaagtgtgacaacatcttcatcaccgggcccaccggctccgtgaagatt
ggcgacttgggtctggccaccctgaaaagagcatcttttgccaaaagtgtaataggtacc
cccgagttcatggcacccgaaatgtacgaggagcattacgacgagtcggttgatgtctac
gctttcgggatgtgcatgctggagatggccacctcagagtatccctattcggagtgccag
aacgccgcccagatctatcgcaaggtcacctgtggcatcaagccggccagctttgagaag
gtgcatgatcctgagatcaaggagatcatcggagagtgcatctgcaagaacaaagaggag
aggtacgagattaaggacctgctgagccacgccttcttcgcggaagacacgggcgtccgg
gtggaacttgcagaggaggaccatggcaggaagtctaccatagccctgcggctttgggta
gaagaccccaagaagctgaagggcaagcccaaagacaatggagcgatagagtttaccttt
gacctggagaaggagacccccgacgaggtggcccaagaaatgattgattccggatttttc
catgagagtgatgtgaagattgtggccaagtccatccgggaccgggtagcactcattcaa
tggcgtcgtgagaggatctggcctgcactgcagtctcaggagccaaaggacacaggcagc
cctgacaaggccaggggtctgccagcacccctgcaggtccaggtgacctaccatgcacag
agcgggcagcctggacagccagaacctgaggagcctgaggcggaccagcatctcctgccc
cctaccttgccagctagcgttacctccttagcctcggacagcacctttgacagtggccag
ggctctaccgtgtactcggactcccagagcagccagcatagcatggtgctcagctccctc
gtggacacagctccaaccccagcctcgtgcgtatgcagcccccctgtgagtgaggggccc
ggcttgacacacagcctgcctaaactaggggccttccagcagccagccgctgtgcctggc
ctatcagtgggccctgtgccaccccctgcccgccctccactcctccagcagcattttcca
gagccttccatgagcttcacccctgtgctgccaccacccagcacccctgtgcccacgggc
ccaagccagccagcacccccagttcagcagcctcttccaatggcccagccacctaccctg
ccgcaggtcctggccccacagcccatgggcactgtccagccagtgccctctcatttgcct
ccatacctggctccaacctcccaggtagtggcccctgctcagctgaagcctctccagatg
ccacagccacctctacaacctcttgctcaagtccctccgcagatgcctcaaatgcctgtg
gttccccccatcactcccttagcaggactcgacggcctccctcagaccctcgctgacctg
ccggctgcaaacgtggcccctgtgccgccacctcagtatttctcacctgctgtgatcttg
ccaagcctcacaacgcccctgcccacatcaccggccctgcctctgcaggctgtcaagctg
cctcacccccctggggcacccctggctgtgccctgtcagaccatcgtgccaaacgcacca
gctgctatccccctcttggccgtggccccgcagggtgtggccgcactgtccatccatcca
gcagtggcccagatcccagcccagatcccagcccagcctgtgtacccagcagccttccca
ggaatggtacctggagacgtccctccctcaccccaccacacagtgcagagcttacgggcc
acccctccacagctggcctcgtctgtgcctcctcagtctgtccagcccagtgtcgttcat
ctacctgagcaggctgctccatctgctgcctcagggacccaggtcctgctgggccaccct
ccttcgtacaccacggatgttgctgctccagtctctgctgtgtccctgccgcctgctgtc
ctttcccctcctctgccagatactctgctgcctactgtccctgagctcctgcccaagctc
cccagctctctggcccctacggtggtcgcagcttctcagagtgtgcccacacagacctct
acactcctcccaccaacaaacccacctctgcccactgggcctgcagtcgctggcccctgc
cctgctgtccagctgacggtggaagcagctcaagaggagcaggtctcacaagacaaaccc
ccgggccccccacagagctgtgagagcttgggaggttctgatgtcacctctggaagagat
ctgagtgacaactgtgaaggcacctttggaacgggcaggctggagggaagggctgcccgg
aaacaccaccgtaggtccactcgtgcacgctcccggcaggagagggccagccggccccgg
ctcactatcctgaatgtgtgtaacacgggggacaagatggtggagtgtcagctggagacg
cataaccacaagatggtgaccttcaagtttgacctcgatggggacgctccagatgagatt
gccacatacatggtagagcatgacttcatcctgcccgctgagcgagagacgtttatcgag
cagatgaaggacgtcatggacaaggcagaagatatgctcagtgaggacacggatgctgat
catggctctgatacagggaccagccctccacacctgggtacctgtggtctgaccacgggg
gaggagaatggacagtcccaagccaatgcccctgtctatcagcagaatgtcttgcacacg
gggaagaggtggtttatcatctgtccagtggctgagcacccagcagcagacacttctgag
tcatcacccccacttcctctaagctctttgcagccagaagccagccaagacccagcaccc
tatccagaccagctgtccttgacggacaaacccagtttcccagctgctcagcagctcctg
agccaggcaggctccagcaaccctcctggtggagcatcagcccccacggccccatcttcc
cctcctgtgacttctgtaatgcccgcagcaccagccaccagcaccgtgccagagtcagca
gcagggactgccatgcaggcaggaggtccagggactcatcaaggaccagccagtgttcat
gagaccctccacccactggccgagacacatcgtgcccagggtgctgcccagccccttagc
actggccaaggaccttgcactccagctctggaggcctctcactgctccacaggtctggga
gagcccatctcaaccaaggaggtcagcactcaaggagggaccctgtctgcttcaatgcca
gagcccagccctcccactggggctgtacaatctgtaccgagtcagccaccacccccactg
cccatcacagtggggactataggtctggcagctccccagcttcccagtccccctctgggg
cctactgctcccccaccaccaccctcagccttggaatctgatggggaagggccaccccct
agggtgggcttcgtggacaacaccatcaagagtctggatgagaaactgcggactctgctc
taccaggagcatgtgcccacctcctcagcctcggctgggacccccttggaggcaaacgac
agagacttcaccctggagccccttcgaggagacctcccctcggccttgagtgacaagacc
ccaagcctcacccagcagagccagccctcattggaaaagtcagaaacggctcctgcaggg
tgggccctggccccgcgggaacagggtgcgtcctcttcaatgacagcagagtcctcttcc
agcaacacactgggctgtgacagtgacacagggcaggtggcctcggactcccccacagca
cccagtgtcccccaggatacctccgtttcttccgtccctacgcacatggatcccaaagat
cagaatggtagtgctcccagagaaaccttggtagcacccatgcagagttgcccagggacc
ttcacagagggcagcccagcccagctgcgtggcgtccgggactccgggtccccccataag
cggccagggcagcaggacagcagttctccagccaaaactgtgggccgcttctccgtggtc
agcacacaagacgagtggactctggcgtcacctcacagcctgcggtactccgccccacct
gatgtctacctggatgagatcccctctagccctgaggtgaagctggcagttcgtcgagta
cagacagcctcctccatcgaggttggcgttgaggagcctgcctccagtgactctggggat
gaatgcccaagaaggaggacccaggtgcagaagcagtcctccctgccggggagcggtggc
gtggcaagtgactttgtgaagaaggccactgccttcctgcacaggtcatcaagggctggc
tcgctgggccctgagacacccagcagggcaggtgtgaaggtccctaccatcagtatcacc
tccttccactcccagtcatcctacatcagcagtgacaacgactcggagtttgaggacgca
gacataaagaaggaactgcgcagcctgcgggaaaagcacctgaaggaaatctctgagcta
cagagccagcagaaacaggagattgaagccctgtacagacgcttgggcaagccgctccct
cccaatgtggggttcttccacaccgcaccccctatgggccgcaggagaaaaaccagcaag
agcaaattgaaggcgggcaagctgctgaatcccctggtgcaacagctcaaggtcgtggcc
tccagcacagggtcagccctgaagcgtctctgcctaggcaaagaacacagcagtaggtct
tccaccagcagcctggccccaggccctgagccaggtccccagcccaccctgcacgtccag
gcgcaggtgaacaacagcaacaacaagaagggcaccttcacggatgatctgcacaagctg
gtggatgagtggacaacgaagacagtgggggcggcccaagtgaagcccacgctcaaccag
ctgaagcagacgcagaagctgcatgacatggaggcctctggagaggctcgggctacatct
gtgcctcgaggaggagtggcaacatcgtgtctggccccagcacctggccctctgtccagc
acagccattcctggagtcaccccagccctgcctgtgcccacaccagatcctgagagtgaa
aagcccgactga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (21)   
   RefSeq(pep) (21)   
DNA sequence (23)   
   RefSeq(nuc) (21)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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