KEGG   Rattus norvegicus (rat): 308457
Entry
308457            CDS       T01003                                 
Symbol
Egln2
Name
(RefSeq) prolyl hydroxylase EGLN2
  KO
K09592  hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04066  HIF-1 signaling pathway
rno05200  Pathways in cancer
rno05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    308457 (Egln2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    308457 (Egln2)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    308457 (Egln2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.29  hypoxia-inducible factor-proline dioxygenase
     308457 (Egln2)
SSDB
Motif
Pfam: 2OG-FeII_Oxy_3 2OG-FeII_Oxy_4 2OG-FeII_Oxy
Other DBs
NCBI-GeneID: 308457
NCBI-ProteinID: NP_001004083
RGD: 631376
Ensembl: ENSRNOG00000020947
UniProt: Q6AYU4
Position
1:complement(91579205..91586985)
AA seq 415 aa
MDSPCQPQALNQALPQLPGSVSESLEPSRARMGVESYLPCPLLPSYHRSGASGEASAGNG
TPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRK
WAKDGGDAPSPSKRPWARQENQEAKGESGVGCDSGGGSSNSTTHSSGEASSRLREEAQPS
APERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPP
RSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGL
GYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWS
DRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPATPT
NT seq 1248 nt   +upstreamnt  +downstreamnt
atggacagcccgtgccagccgcaggccctgaatcaagctctccctcagttgccagggtct
gtgtcagagtccttggagcctagccgagccaggatgggggtggagagttacctgccctgt
cctctgctcccctcctaccaccgttcaggagcatctggggaggcctcggctggcaacggg
acccccagaaccacagccactgctactactaccactgccagtcccctgcgggagggcttt
ggtgggcaggatggtggtgagctgtggccactgcagagtgaaggtgctgctgcgttggtt
accaaggagtgccagcgactggcggcccagggtgcccgacctgaggcccccaaacggaag
tgggccaaggatggtggggatgccccttcacccagcaagcgaccgtgggccaggcaagag
aaccaggaggccaagggggaaagtggtgtgggctgtgacagcggtggcggcagcagcaac
agcactacccatagcagtggcgaggcaagttctaggctgagggaggaagcccagccctct
gcacctgagcgcctggccttggactatattgtgccttgcatgcggtactatggtatctgc
gtcaaggacaacttcttgggggcagtactgggtggccgtgtgctggctgaggtggaagcc
ctgaagtggggcgggcgtctacgtgatgggcaactagtgagccagcgggcgatcccaccg
cgcagcattcgtggggaccagattgcctgggtagaaggccacgagccaggctgccggagc
attggtgccctcatggctcatgtggacgcagtaatccgccactgtgcagggcggctgggc
aactacgtcatcaatgggcgcaccaaggccatggtggcgtgttacccaggcaatgggctc
gggtacgtgaggcatgttgacaatccccacggcgatgggcgctgcatcacctgtatctat
tacctgaatcagaactgggatgttaaggtgcatggcggcctgctgcagatcttccctgag
ggtcggccagtggtagccaacatcgagccactctttgaccggttgctcattttctggtct
gaccgacggaatccacatgaggtgaagccagcctatgccaccaggtacgccatcactgtc
tggtattttgatgccaaggagcgggcagcagccagagacaagtatcagctagcatcggga
cagaaaggtgttcaagtacccgtgtcacagccagctacacctacctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (32)   

Download RDF
DBGET integrated database retrieval system