KEGG   Rattus norvegicus (rat): 308776
Entry
308776            CDS       T01003                                 
Symbol
Pde8a
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
  KO
K18437  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno01100  Metabolic pathways
rno04927  Cortisol synthesis and secretion
rno04934  Cushing syndrome
rno05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    308776 (Pde8a)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    308776 (Pde8a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    308776 (Pde8a)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    308776 (Pde8a)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     308776 (Pde8a)
SSDB
Motif
Pfam: PDEase_I PAS_9 PAS PAS_4 PAS_3 PDE8 PAS_8 Response_reg
Other DBs
NCBI-GeneID: 308776
NCBI-ProteinID: NP_942062
RGD: 735125
Ensembl: ENSRNOG00000019005
UniProt: Q76KC6
Position
1:144575203..144698216
AA seq 823 aa
MGCAPSIHISDNRVSNPSDSDGEDEDVRVPALRSRQRWSTPPGLVEPQPRDSGASKVSVA
DVQFGPMRFHQDQLQVLLVFTKEDSQCNGFYRACEKAGFKCTVTKEVQTVLACFQDKLHD
IIIIDHRNPRQMDAEAMCRSIRSSKLSENTVIVGVVRRVDKEEVSLMPFLAAGFTRRYIE
NPNVMACYNELLQLAFGEVRSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAFET
TMGYQSGELIGKELAQVPINEKKGDLLDAINSCVTIDKEWQGVYHTQKKNGDNIQQNVKI
IPVIGQGGKIRHYVSIIRVCNGSNKVETTTECVQTDSQTDSQAGKHKDRRKHSMDVKAVS
SRTSEVSNQRRHSSLARIHSMMIEAPITKVINILSAAQENSPVSVTEALNHVLDILRTTE
LYSPQFNTEDDPHATDLVGGLMSDGLRRFSGNEYTLATKSLRPSSSQLAVPISLHDIPPR
IAQVIENEEQWDFDIFELEAATQNRPLIYLGLKTFARFEICEFLQCSEATLKSWFQIIES
NYHSSNPYHNSTHAADVLHATAYFLSRNKLKDTLDRLDEVAALIAATIHDVDHPGRTNSF
LCNAGKELAVLYNDTAVLESHHAALAFQLTLENDKCNIFKNTDRNDYRTLRQSIIDMVLA
TEMTKHFEHVNKFINSINKPLKAQKNEVQETGRSLEDIRAMVRTPESRTLIKRMMIKCAD
VSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFVYLPNLMRHLEDNFKYWKGLDEKELCTLRPPPE
NT seq 2472 nt   +upstreamnt  +downstreamnt
atgggctgcgccccgagcatccacatttccgacaaccgagtgtcgaaccccagcgacagc
gacggcgaggacgaggacgtccgggtccccgcgctgaggtctagacagcgatggtcgacc
ccgcccgggctcgtggagcctcagcctcgcgacagcggtgcctcgaaggtatcagttgct
gatgtgcaatttggcccgatgagatttcatcaagaccagcttcaggtacttttagtgttt
accaaagaagatagccagtgtaatggattctacagggcatgtgaaaaagccgggtttaag
tgcacagtcaccaaggaggtgcagactgtccttgcctgtttccaggacaaactccatgac
atcatcatcatagaccacagaaatccccgacagatggatgcggaggcaatgtgcaggtct
atcagatcatcaaaattatcagaaaacacagttattgttggcgtagtacgcagggtggac
aaagaagaggtgtctttaatgcccttccttgccgctggcttcacgcggaggtatatagaa
aaccccaacgtcatggcctgttataatgaactgctccagttggcatttggagaggtgcga
tcacagctgaaactcagggcttgtaactcagtgttcactgcgttagagaagagtcaagaa
gcgattgagatcacaagtgaggaccacatcatccagtatgcaaaccctgcatttgaaaca
acaatgggttatcagtcgggagaactaatagggaaggagttagcacaagtgcccatcaat
gagaagaaaggtgacttgctggatgccataaattcctgtgtcacaatcgacaaggagtgg
caaggagtttaccatacccaaaagaaaaatggagataacatccaacaaaatgtgaagata
atacctgtcattgggcagggaggaaaaatcagacactatgtgtccattatcagagtgtgc
aatggcagcaataaggttgagaccacaactgagtgtgttcagactgatagtcaaacagat
agtcaggcaggcaagcataaagacaggaggaaacattcgatggacgtcaaagcggtttcc
tccagaacaagcgaagtttccaatcagagaagacattcctctctggcccggatacattct
atgatgattgaggcaccaatcaccaaggtaatcaatattcttagtgctgcccaggaaaac
agtcctgtgtctgtgacagaagccttgaaccatgtgctggatatcctgagaaccactgaa
ctgtattcaccccagtttaatactgaggatgaccctcacgccactgacctcgttgggggc
ttaatgtctgatggcttacggaggttttcaggaaatgagtatactcttgcaacaaaaagc
cttcggccatcttcaagccagttggccgtccccatctcccttcatgatatcccaccacgg
attgctcaggtcatagaaaatgaggagcaatgggactttgacatttttgagctggaagct
gcaacccaaaataggcctttgatttatctaggtctcaaaacgtttgctcgttttgaaatc
tgtgagttcttacagtgctctgaggcaacgctgaaatcatggtttcaaattattgaatcc
aattaccattcctctaacccctaccacaattccacgcacgccgcggatgtgcttcacgcc
actgcgtatttcctttccagaaacaagttaaaggacactttagatcgccttgatgaggtc
gctgccctcatcgctgccaccatccacgatgtggatcaccccgggagaaccaactctttc
ctctgcaatgcgggaaaggagctggccgtactgtacaatgacactgctgtgctagagagc
caccacgcagcgctggccttccagctgacccttgaaaatgacaaatgcaatatctttaaa
aacacagacaggaatgactaccggacactacgccagagtatcattgacatggtcctagcc
acagagatgacaaagcactttgaacacgtcaacaaatttatcaacagcatcaacaagcct
ctgaaagcacagaaaaacgaggttcaggaaactggcagaagtctggaagatataagagcc
atggtcaggactccagagagccggactctcatcaaaaggatgatgattaagtgtgccgac
gtgtccaacccctgccggcccctcgagcactgcatcgagtgggctgcacgcatctcagag
gagtatttctcccagaccgatgaagagaaacagctggacttgcctgtggtgatgccagtg
tttgacagaaacacctgcagcatccccaagtctcagatctccttcatcgactacttcatc
acagacatgtttgatgcctgggatgcctttgtttacctgcctaaccttatgcggcacctg
gaggacaacttcaagtactggaaaggactggatgagaaggagctgtgcaccctccggccc
cctccagaatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (10)   
   RefSeq(nuc) (8)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (46)   

Download RDF
DBGET integrated database retrieval system