KEGG   Rattus norvegicus (rat): 310159
Entry
310159            CDS       T01003                                 
Symbol
Drosha
Name
(RefSeq) ribonuclease 3
  KO
K03685  ribonuclease III [EC:3.1.26.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03008  Ribosome biogenesis in eukaryotes
rno05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    310159 (Drosha)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    310159 (Drosha)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    310159 (Drosha)
   03009 Ribosome biogenesis [BR:rno03009]
    310159 (Drosha)
   03036 Chromosome and associated proteins [BR:rno03036]
    310159 (Drosha)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.26  Endoribonucleases producing 5'-phosphomonoesters
    3.1.26.3  ribonuclease III
     310159 (Drosha)
Messenger RNA biogenesis [BR:rno03019]
 Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Ribonucreases
     310159 (Drosha)
Ribosome biogenesis [BR:rno03009]
 Eukaryotic type
  90S particles
   RNase
    310159 (Drosha)
 Prokaryotic type
  rRNA processing factors
   310159 (Drosha)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Gene silencing
   microRNA pathway
    Microprocessor complex
     310159 (Drosha)
SSDB
Motif
Pfam: Ribonuclease_3 Ribonucleas_3_3 dsrm
Other DBs
NCBI-GeneID: 310159
NCBI-ProteinID: NP_001101125
RGD: 1307626
Ensembl: ENSRNOG00000013451
UniProt: E9PTR3
Position
2:63591885..63703688
AA seq 1373 aa
MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPTYRPQNLRLLHPQQPPAQYQYEPPSAPSS
SFSNSQAPNFMPPRPDFVPYPPPVAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMP
PPMPCPNNPPVSGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPNF
NSFQNNSSSFPPSANNSSTPHFRHLPPYSLPKAQSERRSPERLKHYDDHRHRDHSHGRGE
RHRSLERRERGRSPERRRPESRYRSEYDRGRTPPPRHRSYERSRERERERHRHRENRRSP
SLERAYKKEYKRSGRSYGLPVTPEPAGCTAELPGEIIKNTDSWAPPQENVNHRSPSREKK
RARWEEEKDRWSDSQSSGKEKSYTSIKEKEPEEAPPEKTEEEDEELLKPVWIRCTHSESY
YSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSS
ESECETDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAK
ARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIF
EGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYD
WNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIAN
MLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQ
LSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVE
LSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPS
HHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSR
INHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRF
MLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGTLEEAKQLFGRLLFNDPDLREVWLNY
PLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLG
HNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAI
TNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDP
KSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAE
MGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDEAEDIKK
NT seq 4122 nt   +upstreamnt  +downstreamnt
atgcaaggcaatacgtgtcatagaatgtcttaccacccaggacgagggtgtccccgggga
cgaggaggacatggagccagaccctcagcaccgacttacaggccccaaaatctgagactt
cttcaccctcagcagcctcctgcgcagtatcaatatgagcctcccagtgccccctcttcc
tcgttctcgaactctcaagcccccaactttatgcccccacggcctgactttgtcccttac
cctccaccagttgcaccgtcagcacagggccctctcccaccctgcccagttaggccccct
taccccaaccaccagatgagacaccctttccctgtgcctccctgttttccacccatgccc
cctccaatgccttgtcccaacaaccccccagtctccggagcacctcccggccaaggcact
ttccccttcatggtcccccctccttccatgccccaccccccaccccctcccgtcatgccg
cagcaggttaattatcagtaccctcctggatactcgcacagtttcccgcctcccaatttc
aacagttttcagaacaactccagttctttcccacccagtgctaataacagcagcacccct
cattttagacacctccctccatactcacttcccaaggctcagagtgagagaaggtcccca
gagaggcttaagcactacgatgaccacaggcaccgagatcacagtcacgggcgaggtgag
aggcatcggtccctggagcgcagagagcgcggccgcagcccggagaggagaagacctgag
agccgctaccgctcggaatatgatcgggggaggacgccaccgccgcgccatcgcagctac
gaaaggagcagagagcgggaacgagagagacacaggcaccgggaaaaccgcagatcaccg
tctctggaaagggcctacaaaaaggaatataagagatctggaaggagctatggcttacca
gtcactcctgagccggctggatgcacagcagaattacctggggagattattaaaaataca
gattcttgggccccaccccaggagaatgtgaatcatcgttctccaagcagggagaagaag
agagcacgttgggaggaggaaaaagacaggtggagtgacagccagagctctggcaaagag
aagagctatacgtccatcaaagaaaaggaaccagaggaggcgccgcctgagaaaaccgag
gaagaggacgaagagctcctcaagcccgtgtggatccgatgcacacactcggaaagttac
tactccagtgaccccatggatcaggtgggagactctactgtcgtaggaacaagcaggctc
cgggatctgtatgacaaatttgaggaagagttggggaacaggcaagagaaggccaaagct
gcccggcctccatgggagcccccaaagacaaagctggatgaagatttagagagctccagt
gagtctgaatgcgagacggacgaggacagcacctgctcaagcagctcggactcggaggtg
ttcgatgtcattgcagagattaaacgcaaaaaggctcaccctgaccgacttcatgatgaa
ctttggtacaacgacccaggccagatgaacgacggaccactttgcaaatgcagtgcaaaa
gcaagacgcacaggaattcggcacagcatttatcccggagaagaggcaatcaagccctgt
cgtcctatgaccaacaacgctggacgacttttccactaccggattaccgtctccccgcct
accaactttttaacggacaggccaacagtcatagaatacgatgatcatgagtatatcttt
gaaggattttctatgtttgcacatgcccctctgaccaatattccactgtgtaaagtaatt
cgattcaacatagactacacgattcattttattgaagagatgatgcctgagaatttttgt
gtgaaaggacttgaactgttttcattgttcctattcagagatattttggagttatacgac
tggaatcttaaaggtcctttgtttgaagacagccctccctgctgtccaagatttcatttc
atgccacgttttgtaagatttcttccagatggcggcaaagaagtgttatcaatgcaccag
attcttctctacctgcttcgctgtagcaaggctttggtccctgaggaggagattgccaat
atgctccaatgggaggagctcgagtggcagaaatatgcggaagagtgcaaaggcatgata
gttaccaaccctgggacgaaaccaagctctgtccgcatcgatcaactggatcgtgagcag
ttcaaccctgaagtgatcacttttccgattatcgttcactttgggatacgccctgcacag
ttgagttatgcaggagacccacaataccaaaaattatggaaaagttacgtgaaacttcgc
cacctcttagcaaatagtcccaaggtcaaacagactgacaaacagaagctggcgcagagg
gaggaagcgctccagaagatacggcagaagaacacaatgcgtcgagaagtcaccgtggag
ctgagtagccaaggattctggaaaactggcattcgttctgatgtctgtcagcacgcgatg
atgctgcctgttctgacccatcacatccgataccatcaatgcttaatgcacttggacaag
ttgatagggtatacttttcaggatcgttgtctgctccagctggccatgactcatccgagt
catcatttaaattttggaatgaatcctgatcatgccaggaattctctgtctaactgtgga
attcgacagcccaaatatggagacagaaaagttcatcacatgcacatgcggaaaaaagga
attaacaccctaataaatatcatgtcacgcctcggccaagatgatccaactccttcaagg
attaatcacaatgaaaggttggagttcctgggagatgctgttgttgagtttctgaccagt
gtccacctgtactatttgtttcctagcttggaggaaggaggcttggcaacctatcggaca
gccattgttcagaatcagcacctcgccatgctcgcaaagaaacttgaactggatcgattt
atgctgtatgcccatgggcccgacctatgtagagaatcagacctccggcatgcgatggcc
aattgtttcgaagcattgataggagctgtttacttggaggggaccctggaggaagccaaa
cagttgtttggacgcttactctttaatgatccggacctgagagaagtctggctcaattat
cctctccacccactccaactacaagagccaaatacagatcgacaacttattgaaacttcc
ccagttctacagaaactgaccgagtttgaagaagcaattggggtgatcttcactcacgtc
cggcttctggcacgggcattcacactaagaactgtgggctttaaccacctgaccctaggc
cacaatcagaggatggaattcctgggtgactccataatgcagctggtagccacggagtac
ttgttcatccacttccccgaccaccacgaaggacacttgacgttgttacgaagttcttta
gtgaacaacagaactcaagccaaggtagcagaggaactgggcatgcaagagtatgccatc
accaacgacaaaaccaagagacccgtggccctaagaaccaagactttggcagaccttttg
gaatcatttattgcagccctgtacatcgacaaggacttggaatacgtccatactttcatg
aacgtctgcttctttccacgtctgaaggagttcattctgaaccaggactggaatgacccc
aagtcgcagctgcagcagtgctgcctgaccctgaggactgaagggaaagaaccagacatc
cccttgtacaagactctgcagacagtggggccgtcccacgctagaacctacacggtggcc
gtttacttcaaaggagagaggataggctgtgggaaaggaccaagtattcagcaggccgaa
atgggagcagcaatggacgcacttgagaaatataactttccccagatggctcatcagaag
cggttcattgaacggaaatacagacaagagttaaaggaaatgaggtgggaaagagagcat
caggagagagagccggatgaggctgaagacataaagaagtaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (13)   
   RefSeq(nuc) (7)   
   GenBank (3)   
   EMBL (3)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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