KEGG   Rattus norvegicus (rat): 310635
Entry
310635            CDS       T01003                                 
Symbol
Arhgef2
Name
(RefSeq) rho guanine nucleotide exchange factor 2
  KO
K12791  Rho guanine nucleotide exchange factor 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04530  Tight junction
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    310635 (Arhgef2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    310635 (Arhgef2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    310635 (Arhgef2)
Membrane trafficking [BR:rno04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    310635 (Arhgef2)
SSDB
Motif
Pfam: RhoGEF PH_16 PH C1_1 C1_2 Prok-RING_1 TrbK zinc_ribbon_9 PHD ACP_PD
Other DBs
NCBI-GeneID: 310635
NCBI-ProteinID: NP_001012079
RGD: 1304659
Ensembl: ENSRNOG00000020027
Vega: OTTRNOG00000002424
UniProt: Q5FVC2
Position
2:176358909..176416178
AA seq 985 aa
MSRIESLTRARIDRSKEQATKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSI
TAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLRNNTALQSVSLRSKTTTRERP
TSAIYPSDSFRQSLLGSRRGLSSLSLAKSVSTTNIAGHFNDESPLGLRQILSQSTDSLNM
RNRTLSVESLIDEGVEVFYNELMSDFEMDEKDFEADSWSLAVDSSFLQQHKKEVMKKQDV
IYELIQTELHHVRTLKIMTRLFRTGMLEELQMEPEVVQGLFPCVDELSDIHTRFLSQLLE
RRRQALCPGSTRNFVIHRLGDLLISQFSGSNAEQMRKTYSEFCSRHTKALKLYKELYARD
KRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVLINRILQNSHGIEEEYQDLAAAL
GLVKELLSNVDQDVHELEKEARLQEIYNRMDPRAQTPVPGKGPFGRDELLRRKLIHDGCL
LWKTATGRFKDVLLLLMTDVLVFLQEKDQKYIFTSLDKPSVVSLQNLIVRDIANQAKGMF
LISSGPPEMYEVHAASRDDRTTWIRVIQQSVRLCPSREDFPLIETEDKAYLRRIKTKLQQ
KNQALVELLQMNVELFAEMVHFQALKAGFIGMPPPTLPRGLFRLESFESLRGERLLKDAL
REVEGLKDLLLGPCVDLPLTAREPALPVEADSGSCPGVTANGEARTFNGSIELCRADSDS
SQKDRNGNQLRSPQEEALQPLVNLYGLLQGLQAVVVQQERLMEALFPEGPERWEKLSRAN
SRDGEAGRAAVASVTPEKQATELALLQRQHSLLQEELRRCQRLGEERATEAGSLEARLRE
SEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSFNPPQ
PSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTCSEEEVSSRLSPPHSP
RDFTRMQDIPEETESRDGEPTASES
NT seq 2958 nt   +upstreamnt  +downstreamnt
atgtctcggatcgaatccctcactcgcgcgcggatcgaccggagcaaggagcaggcgacc
aagacccgggaaaaggagaagatgaaggaagctaaagatgcccgctataccaacggccac
ctcttcaccaccatctcggtctccggcatgactatgtgctatgcctgtaacaagagcatt
acagccaaggaagccctcatttgtcccacatgtaacgtgaccatccacaaccgctgtaag
gacacgctggccaactgtaccaaggtcaagcagaagcaacagaaagctgcactgctgagg
aacaacactgccttgcagtccgtctctctccgaagtaagacaaccaccagagagcggcca
acgtctgccatctacccttccgatagcttccggcagtccctcctgggttctcgtcgtggc
ctgtcctccttgtctttggccaaaagtgtttccactaccaacattgctggacatttcaat
gatgagtctcctctggggctgcgtcagatcctctcccagtccacagactccctcaacatg
cggaaccgaaccctgtccgtggagtcccttattgatgaaggtgtagaagtgttctacaac
gagctcatgagtgactttgagatggacgagaaggacttcgaggcggattcatggagcctt
gctgtggacagcagcttcctgcaacagcataaaaaggaggtgatgaagaagcaagatgtc
atctacgagctgatccagaccgagctgcaccatgtgagaaccttgaagattatgacccgc
ctcttccgcactgggatgctggaagagttgcagatggagccagaagtggtccagggactg
ttcccctgtgtggacgagcttagtgacattcacacacgtttccttagtcagcttttggaa
cggcggcgccaggccctgtgtccaggcagcacccggaactttgtcatccatcgtttgggt
gacttgctcatcagccagttctcaggttccaacgctgagcagatgcgcaagacttactca
gagttctgcagccgccacaccaaggccttaaagctctataaggagctgtacgctcgagac
aaacgcttccaacagttcatccggaaaatgacccgctctgctgtgctgaagcggcatggg
gttcaggagtgcattctcctggtaactcagcggattaccaaatacccagtgctcatcaac
aggatcctgcagaattcccatgggattgaagaggagtaccaagacttggcagcagcccta
gggctagtaaaggagttgttgtccaatgtggaccaggatgtacacgagctggagaaagag
gcccgccttcaggagatttacaaccgaatggatcctcgggctcagacccctgttcctggc
aagggccccttcggccgagatgaacttttgcggagaaaacttatccatgatggctgcctg
ctctggaagacagccacaggccgctttaaagatgtcctcttactactgatgacagatgtg
ctggtgtttctccaggaaaaggaccagaagtacattttcacgtccctggacaagccctca
gtggtatccttgcagaatctcatcgtaagagacattgccaaccaggcgaaagggatgttt
ctgatcagttctggcccacctgaaatgtatgaagtacacgcagcatctcgagatgaccgt
actacctggatccgtgtcatccagcagagcgtgcgcttatgcccgtcgagggaggacttc
cctctgatcgagacagaggataaggcgtacctccggaggatcaagacgaaactgcagcag
aaaaaccaggcgctggtggagctgctacagatgaatgttgagctatttgctgagatggtc
cacttccaggcattaaaagctggtttcatcggaatgcccccgcccaccctgcccaggggc
cttttccgtcttgagtcctttgagtcccttcgaggcgagcgtctgctcaaagatgccctc
cgtgaagtggaaggcctgaaagacctgttgttgggcccttgtgtggacctgcctttgaca
gcccgagaaccagccttacccgtagaagctgacagtggtagctgtcctggggtcactgcc
aacggagaggccagaaccttcaatggctccattgagctctgtagagcagactcagattcc
agccagaaggatcggaatggaaatcagttgaggtcaccacaggaggaggcgttacaacca
ttggtcaatctgtatggactcctacaaggcctgcaggctgttgtggtccagcaagaaaga
ttgatggaagccctgttccctgaaggccctgagcggtgggaaaagctatcccgagccaac
tctcgggatggcgaagctggccgggctgcggttgcttctgtaactcccgagaagcaggcc
acggagctggcattactgcagaggcagcacagcctgttgcaggaagagctgcggcgctgc
cagcggctcggggaagagcgggcaactgaagctggcagcctggaggccaggctgcgggag
agcgagcaagcccgggccctgctggagcgggaggctgaagagatccgccggcagctagca
gccttgggccaaaacgagccactcccggcagaagcaccctgggctcgcaggcctctggac
cctcggcgccgcagccttccagcaggcgacgctctgtacttgagcttcaatcccccccag
cctagtcgaggccatgaccgcctggatttgcctgtgactgttcgttccctccaccgaccc
tttgatgaccgagaggcacaagaacttggtagccccgaggatcgactgcaggacagcagt
gaccctgatacttgcagtgaggaggaagtcagtagccggctgtccccaccccacagtcca
cgagacttcacccgaatgcaggacattcccgaagagacagaaagccgagatggggagcct
acggcctcagagagctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (15)   
   RefSeq(nuc) (11)   
   GenBank (2)   
   EMBL (2)   
Protein domain (10)   
   Pfam (10)   
All databases (50)   

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