KEGG   Rattus norvegicus (rat): 310638
Entry
310638            CDS       T01003                                 
Symbol
Ash1l
Name
(RefSeq) histone-lysine N-methyltransferase ASH1L
  KO
K06101  [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00310  Lysine degradation
rno01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    310638 (Ash1l)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:rno03036]
    310638 (Ash1l)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     310638 (Ash1l)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     310638 (Ash1l)
SSDB
Motif
Pfam: SET BAH AWS Bromodomain PHD_5 PHD PHD_2
Other DBs
NCBI-GeneID: 310638
NCBI-ProteinID: NP_001101159
RGD: 1306350
Ensembl: ENSRNOG00000020386
UniProt: A0A0G2K2W6 A6J6B3
Position
2:176644393..176780848
AA seq 2918 aa
MDPRNTAMLGLGSDSEGFSRKSPSAISSGTLASKREVEIEGNTDEEDPRKRNRERAIEAG
KDDGLTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTVKHSRK
ALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIECQSEESVHLHSQGENNPLSKKLSPV
HSQMADYIPAAPPLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGT
GTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVSLINK
DSVKKLGTGTTAVFINKDLGKKPGTVTTVGLLSKDPGKKLGIGIVPGLVNKESGKKLGLG
TVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLSCPIAGQLGSKDA
LNLKSEALLPTQEQLKASCSANISNHESQELPESLKDSATSKTFEKNVMRHSKESMLEKF
SVRKEITNLEKEMFNEGTCIQQDSFSSNERGAFETSKHEKQPPVYCTSPDFQIGGASDAS
TAKSPFGAVGESNLPSSSPTVSVNPLTRNPPETSSQLVPNPLLLNSTAEQMEEISESIGK
NQFTAESTHLNVGHRSLGHSISIECKGIDKELNESKSTHLDISRISSSLGKKPSLASDSG
IHTITPSVVNFTSLFSNKPFLKLGAVAAPDKHCQVAESLSTSFQSKPLKKRKGRKARWTK
VVARSTCRSPKGLDLERSELFKNVSCSSLSNSSEPAKFMKTIGASSFVDHDFLKRRLPKL
SKSSAPSLALLADSEKASHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGP
PKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVK
MKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLEDSHRQSVCSVSDL
EMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTV
SSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAG
SALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQ
GSMIQTLAMKKAAKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSG
IGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSY
DKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRI
NFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSY
GMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKK
KHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSEQPQVSMD
TGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKSLINREEQWVSREPSE
SSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSC
RKKLTDSPGLFPVQDTALSRPHRKEPLPSTERAIQSLAGSQSASDKPSQRSSESTNCSPT
RKRSSSESTSSTVNGIPSRSPRLVASLDDSVDCLLQRIVQHDEQESVEKNGDAPITTVSA
PPSSSPGHSYSKERTLGKSDSLLVPAVPSDSCNSIPLLSEKLASRCSPHHIKRSVVEAMQ
RQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSM
QAFQAAQFVNPELNEGEEVSLHLSPDTVTDVIEAVVQSVNLNSEHKKGWKRKNWLLEEQT
RKKQKTVPEEEEQENNKSFIEKPVEIPSPLETPAEPSEPESNLQPVLALIPREKKAPRPP
KKKYQRAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVDVYVDVKPLSG
YEATTCNCKKPDDDTRKGCGDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERF
RAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVID
SYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDVPAGTELTYDYNFHSFNVEKQ
QLCKCGFEKCRGIIGGKSQRMNGLPSHKGSQPASTHRKSARSKEKRKSKHKLKKRRGHPS
EEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHSRDIHST
SLYTRWNGICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKE
ICDGIISYKDSSQQALAAPLLNLPPKKKNADYYEKISDPLDLSTIEKQILTGYYKTVEAF
DADMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEASAQIDEIVGETASEADSSETS
VSEKENSHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPR
PVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLL
SHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIP
LEAVVGTCCVLDLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAF
DHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSERSKPLLKDLGQDDDALPLIEEVLASQ
EQAANEMPSPEEPDQERVTGDVSDAEKKPEESSQEPQLASTPEERRHSQRERLNQILLNL
LEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK
NT seq 8757 nt   +upstreamnt  +downstreamnt
atggaccctaggaatactgctatgttaggattgggttctgactccgaagggttttcaaga
aagagtccttctgccatcagttctggcactctggccagcaagagagaagtagaaatagag
ggtaacacagacgaagaggatcctcgaaagcggaatcgagaaagggccatagaagcagga
aaagacgatggtttgacagatgcacagcaacagttttcagtgaaagaaacaaacttttca
gagggaaatttaaaattgaaaattggccttcaggctaagagaactaaaaagcctccaaag
aacttggagaactatgtgtgtcgccctgccataaaaacaactgtcaagcactcaaggaaa
gcacttaaaagtgggaagatgacagatgagaagaatgaacactgcccttcaaaatgggac
tcttcaaaattgttcaagaaagcaggtgatgctacagccatcgaatgccaatctgaagaa
agtgtccatcttcactctcagggggaaaataaccctttgtctaagaagctttctccagtg
cattcacaaatggccgattacattcctgcagcaccacctcttgttggcagtcgggatcct
gacataaaggacagagcattacttaatggaggaactagtgtaacagaaaagttggcacag
ctcattgctacctgtcctccttccaagtcttccaaggcaaaaccgaagaagttaggaact
ggcactacagtaggattggttagcaaggacttgatcaggaaaccaggtgttggttctata
gctggaataattcataaagacttaattaaaaagcctgctcttagcacagcagttggattg
gtaactaaagatccagggaaaaagcctatgttcaatgcagcagtaagcctgatcaataag
gactctgtgaaaaaattgggaactggcactacagcggtattcattaataaagacttaggc
aaaaagccagggactgtcactacagtaggactgctgagcaaagacccagggaagaagcta
ggaattggtatcgttccagggttagtgaataaagagtctggcaagaaattaggacttggc
accgtagttggactggttaataaagagttgggaaagaaattgagttctacagttggccta
gtggccaaggatgttacgaagaagattgtagcaagctcagcaatgggattggttaataag
gacattggaaagaaattattaagttgccccattgcaggacaactgggcagtaaagatgcc
ttaaaccttaaatctgaagcactgctccccactcaggaacaacttaaggcttcctgtagt
gcaaacataagtaatcatgaaagtcaagaacttcctgagtctctgaaagacagtgctacc
agcaaaacctttgagaagaatgttatgcggcatagtaaagaaagcatgttggaaaagttt
tcagtccgaaaagaaattactaatttggagaaagaaatgtttaatgaaggaacatgcatt
cagcaagacagtttctcatctaatgaaaggggagcctttgagacctcaaagcatgaaaag
caacctcctgtgtattgcacttctcctgactttcaaataggaggtgcctctgacgcatct
acagctaaatctccctttggtgcagtaggagaaagcaatcttccttcctcgtcacctact
gtatctgttaaccctttaaccagaaatccccctgaaacttcttcacagttggttccaaac
ccattacttttaaattctacagcagaacaaatggaagaaatttctgaatctattggaaag
aaccagttcactgctgaaagtacccacttgaatgttggtcataggtcattaggtcatagc
ataagtattgagtgtaaaggaattgataaagaactaaatgaatcaaaaagtacacatcta
gatatttctagaataagttcttccttgggaaaaaagccaagtttggcttctgactctggt
attcatacaattactccttccgttgttaattttactagtttatttagtaacaaacctttt
ctaaagcttggtgcagtagctgcaccagacaagcactgccaggtcgctgaaagcctaagc
actagtttccagtccaaaccattgaaaaaaagaaaagggagaaaagctcggtggactaaa
gtggtggcaagaagcacatgccgatccccaaaaggactagacttagaacggtcagagctt
tttaagaatgtttcctgtagctcactatcaaatagttctgagccagcaaagtttatgaaa
actatcggagcatcgtcttttgtcgatcatgacttccttaaacgccgattgccaaagttg
agtaagtcttcagctccatctcttgctcttttagccgacagtgagaaagcatctcataag
tcttttatcactcacaaactgtcctccagtatgtgtgtcactagtgatcttttgtcggat
atttataagcccaaaagaggaagacccaaatccaaggaaatgcctcaactagaaggtcca
cctaaaaggactttaaaaatacctgcctctaaagttttttctttacagtctaaagaagaa
caagaacccccaattttacaaccagaaattgaaattccttccttcaaacaaagtttgtct
gtatctccttttccaaaaaagagaggcaggcctaagaggcagatgaggtctccagtgaag
atgaagccccctgtactgtcagtggctccatttgttgccactgaaagtccaagtaagcta
gagtctgaaagtgagaaccatagaagtagcagtgatttctttgagagtgaggatcagctt
caggatacagatgacttagaggacagtcataggcaaagtgtctgcagtgtgagtgacctg
gagatggagccggataaaaaaattagcaagcgaaacaatggacaattaatgaaaacaatt
atccgcaaaataaataaaatgaagactttaaagagaaaaaaattgttgaatcagattctt
tcaagttctgtagaatcaagtaataaaggaaaagtacagtccaaacttcataatacagta
tcaagtcttgctgccacgtttggctctaaattggggcaacagataaatgtcagcaagaaa
ggaaccatttacatagggaagagaagggggcgaaaaccaaaaactgtcttaaatggcctt
ctttctggtagccctgccagccttgctgtgcttgaacaaacggctcagcaggcagctggg
tccgcattaggacagatcctccccccgttactgccttcacctgctagtagctctgagatc
cttccatcacctatttgctctcagtcttctgggactagtggaggtcagagccctgtcagt
agtgacgcaggctttgttgaacctagttcagtgccatatttgcatgtgcactcaagacag
ggcagtatgattcagactcttgcaatgaagaaggctgccaaaggcaggaggcggctatct
cctcctactttgttgccaaattctccttctcatttgagtgaactcacatccctgaaagaa
gccactccttccccagttagtgagtctcatagtgatgagaccattcccagtgacagtggc
attgggacagataataatagcacatcagacagggcagagaagttttgtggacagaaaaaa
aggagacattcttttgagcacatttctctgattccccctgaaacttctaccgtcctaaac
agtcttaaagagaaacacaaacacaaatgtaagcgcaggagtcacgattacctcagctat
gacaagatgaaaagacaaaagcgaaaacggaaaaagaaatatccccagcttcgaaatagg
caggatccagacttcatcgcagaactagaggagctgataagtcgtctaagtgagattcgg
attacccatcgaagtcatcatttcattccccgagacctcctgccaactatttttcgaatc
aactttaatagtttctatacacatccttcttttcccttagaccctttgcactacattcgg
aagcctgacttaaaaaagaaaagagggaggccccctaagatgagggaggcaatggcagaa
atgccctttatgcacagccttagttttcctttatctagtactggattttacccttcttat
ggcatgccttattctccttcacccctcactgctgctccgataggattagggtattatgga
cggtatccccccactctctatccaccacctccatctccttcattcaccactccactgcca
cctccctcctatatgcatgctggtcatttattgctcaatcctaccaaatatcataagaaa
aagcataagctccttagacaggaggcttttcttacaaccagcaggactcctctcctttcc
atgagcacctaccccagcgtacctcctgagatggcttatggttggatggtggagcacaaa
cacagacaccgtcacaaacacagagagcaccgttctgaacagccccaggtttccatggat
actggctcctccagatcggtcttggagtctttgaaacgttaccgatttggtaaggatact
gttggagatcgctataagcataaggaaaagcacaggtgtcacatgtcctgccctcatctc
tctccttcaaagagcttaataaacagagaagaacagtgggtttctcgagagccttcagaa
tcaagttctttagccttgggattgcaaacacctttacaaattgactgctcggaaagttct
ccaagtttgtcccttggaggatttactcccaattctgagccagccagcagtgatgaacat
atgaacctttttacaagtgcaataggcagctgcagagtttcaaaccctaactcgagctgc
cggaagaagttaactgacagccctggactctttcctgtacaagatactgcactaagtcgg
cctcacagaaaggaaccgttgccttccactgaaagggcaatacaatcgttggcaggttcc
cagtcagcttccgataaaccttcccagcgatcatcagaaagcacaaattgtagccctacc
cgtaaaaggtcttcatctgaaagtacttcttcaacagtgaatggaattccttccagaagt
cccagattggttgcttctctggatgactctgtagactgtctgttgcagcggatagttcaa
catgatgagcaagagtccgtggagaaaaatggtgatgctccaattacaactgtatctgca
ccaccttcttccagtccaggccatagctacagcaaagagcggaccctagggaaatcagac
agtcttctagtgcctgcagtcccgagtgactcttgtaatagtatcccacttctttctgaa
aagttagcaagcagatgttcccctcatcatatcaagagaagtgtagttgaagctatgcag
cgccaagctcggaaaatgtgcaattatgacaaaatcttggctaccaagaaaaatctggac
catgtcaataaaattttaaaagccaaaaaacttcaaaggcaggccaggacaggaaacaat
tttgtgaaacgcagaccaggtcgacctcggaaatgtcccctccaagctgtggtgtcaatg
caagcattccaggctgcccagtttgtcaacccagaattgaacgaaggcgaagaagtgtcg
ctgcacctaagtccagacacagttacggatgtgatcgaggctgtggttcagagtgtgaac
cttaattcagaacataagaaggggtggaagaggaaaaattggctgttagaagaacagact
agaaaaaagcagaagacagtaccagaggaagaagaacaagaaaacaataaaagctttata
gaaaaaccagttgaaattcccagtcctcttgaaaccccggctgaaccttctgaacctgaa
agtaacttacaacctgtgctggctctcatcccacgagaaaagaaagccccacgtcctcca
aagaagaaataccagagagctgggctgtattctgatgtctacaaaactacagacccaaag
agccgattaatccaactgaagaaagagaagttggagtacactccgggagagcatgagtat
ggactattcccagcacccattcatgttgatgtctacgttgatgtcaaacctctttctggt
tatgaggctaccacctgtaattgtaagaagccagatgatgacaccaggaagggctgtggg
gatgactgcctcaatagaatgatctttgctgagtgttcccctaacacgtgcccctgtggt
gagcagtgctgtaaccaaaggatacagagacatgagtgggtgcagtgtctggaacgattt
cgagctgaggaaaaaggttggggaattagaaccaaagagcccctaaaagctggccaattc
atcattgaatacctgggggaagttgtcagcgaacaagaattcaggaacaggatgattgaa
cagtatcataatcacagtgaccactactgtttaaacctggatagtggaatggtgattgac
agttaccgcatgggaaacgaggccagattcatcaaccacagctgtgacccaaattgtgaa
atgcagaaatggtctgttaacggagtgtaccgcattggattgtatgcacttaaggatgta
cccgctgggaccgagctcacctacgattacaactttcattccttcaatgtagaaaaacag
caactttgtaaatgtggttttgagaagtgtcgaggaatcattggaggcaaaagtcaacga
atgaatggactccctagccataaaggcagccagcctgcaagcacacatagaaagtctgca
cggtcgaaagaaaagcggaagtccaagcacaagctgaagaaaaggagaggccatccctct
gaagagcccagtgaaaacatcaacaccccaacaagattgactccacagttacagatgaag
ccaatgtccaatagagagaggaactttgtgttaaagcatcatgtgttcttggtccgaaac
tgggagaagatccatcagaagcaggaggaagtaaagcacagccgtgacatccactccaca
tccctgtacacccgatggaatggcatctgtagagacgatgggaacattaagtctgatgtc
ttcatgacccagttctctgccctgcagacagcgagatctgttcgcacaagacgcttggca
gctgcagaggagaacctggaagtggctcgggcagcacgcctggcccagatcttcaaagag
atctgcgatggcatcatctcctacaaagattcttcccaacaagctcttgcagctccactg
ttgaatcttcccccaaagaaaaaaaatgctgactattatgagaagatctctgacccgctg
gatctcagcaccatagagaagcagatcctcactggatactacaaaaccgtggaagctttt
gatgccgacatgcttaaggtctttcgaaatgctgagaagtattatgggcgtaaatccccg
attgggagagatgtttgccgcttaagaaaggcctattacagtgcccggcatgaagcttca
gctcaaatcgatgagattgtgggagaaacagccagtgaggcagacagcagtgagacctca
gtgtctgagaaggaaaacagccatgagaaggacgatgatgtgatccgctgcatctgcggc
ctctacaaggatgaaggcctcatgatccaatgtgacaagtgcatggtgtggcagcactgt
gactgcatgggtgtgaacacagacgtggagcactacctttgtgagcagtgtgacccccgg
cccgtggacagggaggtacccatgatccctagaccccactatgcccagcctgggtgtgtc
tactttatctgtttactccgagatgatttgctgcttcgtcagggtgattgtgtgtacctg
atgagggacagtcggcgcacacctgatggccacccagtccgtcagtcctatagactgtta
tctcacattaaccgagataaacttgacatctttagaatcgagaagctttggaagaatgaa
aaagaagaacggtttgcctttggtcaccattatttccgcccccatgaaactcaccactct
ccatcccgtcggttctatcacaatgagctatttcgggtgccactctatgagatcattccc
ttggaagctgtagttgggacctgctgtgtgttggacctttatacgtactgtaaagggaga
cccaaaggagtaaaggaacaagatgtatacatctgtgattatcggcttgacaagtcagca
caccttttttacaagatccatcggaatcgctatcctgtctgcaccaaaccctatgccttt
gatcatttccccaagaagctcactcccaaaagagacttctcacctcattatgtcccagat
aactacaagaggaacggaggacgatcgtcctggaagtctgaacgttcaaagccgctctta
aaagacctcggacaagatgatgatgctttgcccttgattgaagaggtgctggctagtcag
gagcaagcagccaatgaaatgcccagccctgaggagccagaccaggaaagagtcactggg
gacgtcagtgacgctgaaaagaagccagaggagagtagtcaagagccccagttagccagc
acgcctgaggagcgaaggcacagccagagggaacggctcaaccagatcctgctcaacctc
ctggagaaaatacctgggaaaaacgccattgatgtgacctacctgctggaggaagggtca
ggcaggaaactacgaaggcgcactttgtttataccagaaaacagctttcggaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (2)   
   RefSeq(pep) (8)   
DNA sequence (12)   
   RefSeq(nuc) (10)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (51)   

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