KEGG   Rattus norvegicus (rat): 311341
Entry
311341            CDS       T01003                                 
Symbol
Pla2g4b
Name
(RefSeq) cytosolic phospholipase A2 beta
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00564  Glycerophospholipid metabolism
rno00565  Ether lipid metabolism
rno00590  Arachidonic acid metabolism
rno00591  Linoleic acid metabolism
rno00592  alpha-Linolenic acid metabolism
rno01100  Metabolic pathways
rno04010  MAPK signaling pathway
rno04014  Ras signaling pathway
rno04072  Phospholipase D signaling pathway
rno04217  Necroptosis
rno04270  Vascular smooth muscle contraction
rno04370  VEGF signaling pathway
rno04611  Platelet activation
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04724  Glutamatergic synapse
rno04726  Serotonergic synapse
rno04730  Long-term depression
rno04750  Inflammatory mediator regulation of TRP channels
rno04912  GnRH signaling pathway
rno04913  Ovarian steroidogenesis
rno04921  Oxytocin signaling pathway
rno05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    311341 (Pla2g4b)
   00565 Ether lipid metabolism
    311341 (Pla2g4b)
   00590 Arachidonic acid metabolism
    311341 (Pla2g4b)
   00591 Linoleic acid metabolism
    311341 (Pla2g4b)
   00592 alpha-Linolenic acid metabolism
    311341 (Pla2g4b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    311341 (Pla2g4b)
   04014 Ras signaling pathway
    311341 (Pla2g4b)
   04370 VEGF signaling pathway
    311341 (Pla2g4b)
   04072 Phospholipase D signaling pathway
    311341 (Pla2g4b)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    311341 (Pla2g4b)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    311341 (Pla2g4b)
   04664 Fc epsilon RI signaling pathway
    311341 (Pla2g4b)
   04666 Fc gamma R-mediated phagocytosis
    311341 (Pla2g4b)
  09152 Endocrine system
   04912 GnRH signaling pathway
    311341 (Pla2g4b)
   04913 Ovarian steroidogenesis
    311341 (Pla2g4b)
   04921 Oxytocin signaling pathway
    311341 (Pla2g4b)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    311341 (Pla2g4b)
  09156 Nervous system
   04724 Glutamatergic synapse
    311341 (Pla2g4b)
   04726 Serotonergic synapse
    311341 (Pla2g4b)
   04730 Long-term depression
    311341 (Pla2g4b)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    311341 (Pla2g4b)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    311341 (Pla2g4b)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     311341 (Pla2g4b)
SSDB
Motif
Pfam: PLA2_B cPLA2_C2 C2
Other DBs
NCBI-GeneID: 311341
NCBI-ProteinID: NP_001101234
RGD: 1308658
Ensembl: ENSRNOG00000007447
UniProt: D4A1I6
Position
3:127458022..127467637
AA seq 791 aa
MALQTCPVYMQAKVPETHLLTVRVLQASGLPSKDLVTSSDCYVTLNLPTASSGTLQTRTV
KNSRNPVWNQNFHFRIHRQLKNVMELKVFDQDLMTKDDPVLSVLFDVGTLQVGTQRQSFS
LSAQEDGRLEVEFRLQTLTDCEEQLISNGILVAQELSCLHVELKRTGDPKRSERKVQLVV
AAACEGPQEAPVGTGSFRFHYPACWEQELSVHLQDDPHEQLKVPLRTLPSSQLVRLVFPT
SQEPLMRLELKKEDGPKELAVRLGCGPCPEEQAFLSKRKQVVAAALKKALQLDQDLQEDE
IPVIAVMATGGGIRAMTSLYGQLAGLKELGLLDCISYITGASGSTWALANLYEDPEWSQK
DLAGPTEMLKTQVTKSKLGALAPSQLWRYRQELAERARLGYPTCFTNLWALINEALLHDK
PHEHKLSDQREALSRGQNPLPIYCALNSKEKGLSTFEFGEWCEFSPYEVGFPKYGAFIPS
ELFGSEFFMGRLVKQLPESRICFLEGIWSNLFAASLQDSFYWSSEPSQFWDRWAQDQANL
DKEQVSHLKIAEPPTAAGKIAELFTDLLTKRPLAQATHNFMRGLHFHKDYFHHPHFSTWK
ASKLDKFPNQLTPAEPHLCLLDVGYFINTSCPPLLQPTRDVDLILSLDYNLSGAFQQLQL
VSRFCQEQGIPFPSISPSPEEQRQPQECHMFCDPAQPEAPAVLHFPLVNDSFRDHSAPGV
PRTSEEKTAGEVNLSSSNSPYDYTKVTYSQEDVDKLLRLTHYNICNNQDRLREAMHQAVQ
RRRNRRQFRRE
NT seq 2376 nt   +upstreamnt  +downstreamnt
atggctctgcaaacctgcccggtctacatgcaggcaaaggtgccagagacacacctgctc
actgtccgcgtcctccaggctagtggcctgccttccaaggacctagtgacatcctctgac
tgctatgtgactctgaacctgcccacggcctccagcggcacgctccagacacgcacagtc
aagaacagcagaaacccagtctggaatcagaacttccacttccggatccataggcagctc
aagaatgttatggaactgaaagtctttgaccaggacctgatgaccaaagatgacccagtg
ttgtcagtgctgtttgacgtggggactctgcaagttgggactcagcgccagagcttctca
ttgagcgctcaggaggatgggcgcttggaagttgagtttcggctacagactctgacagac
tgtgaggaacagcttatcagcaatggtatcctggtggcccaggagctctcctgcttgcat
gttgaactgaagaggacaggagacccaaagaggtcagagcgcaaagttcaacttgtggtt
gctgcggcctgcgagggtccacaggaagcccctgtgggcaccgggtctttccgcttccat
tatccagcctgctgggagcaagagctcagtgttcatctgcaggatgacccccatgagcag
ctgaaggtgccattgcgaactctaccctcttcgcagctggtgagacttgtcttccccacg
tcccaggagccactgatgaggttggaactcaagaaagaagacgggccaaaggagctggcc
gtgcggctgggctgtgggccctgccccgaggaacaggccttcctaagcaagaggaagcag
gtggtggccgccgccctgaaaaaggccttacagctggaccaagacctgcaggaggacgag
atcccagtgattgctgtgatggccactggtggtgggatccgggcgatgacttcgttatac
ggacagctggctggcctgaaggagcttggccttctggactgcatctcctacatcactggg
gcttcagggtccacatgggcattggccaatctctatgaggacccagagtggtctcagaag
gacctagcagggcccactgagatgctgaagacccaggtaacaaagagcaaactgggcgca
ttggcccccagccagctttggcggtaccggcaagagctggctgagcgtgctcgcctgggc
tacccaacctgcttcaccaacctgtgggcccttattaatgaggccttgctgcacgacaag
ccacatgaacacaaactctcagatcaacgagaggccctgagtcgaggccagaaccctctg
cctatctactgtgcccttaatagcaaggagaagggcctaagcacctttgaatttggcgaa
tggtgcgagttctctccctacgaagtcggcttccccaagtacggagccttcatcccctct
gagctctttggttctgagtttttcatggggcggctggtgaagcagctccctgagtctcgc
atttgcttcctggaaggtatctggagcaatctgtttgcagccagcctccaagacagcttc
tactggtcctctgaacccagccagttctgggaccgctgggcccaggatcaggccaatctg
gacaaagagcaggtctcccatctgaagatagcagaacctcccacagcggctggcaagatc
gcagagctcttcactgacctcctgacaaagcgccccctcgcccaggccacccacaacttc
atgcgcggtctccatttccacaaggactatttccaccaccctcacttctccacctggaaa
gcttccaaactagacaagttccccaaccagctgacacccgccgagccccacctctgcctc
ctggatgttggctatttcatcaacactagttgcccacccctccttcagccaacacgggat
gtggacctcatcttgtcactggactacaacctctccggagcctttcagcagctgcagctt
gtgagccggttctgccaggagcagggcattcctttcccatccatctcgcccagccctgag
gagcagcgtcagcctcaggagtgccatatgttctgtgacccagcccagcccgaagcccca
gctgtgttgcacttccccctggtcaatgactccttcagggaccactcagcccctggggtg
ccacggacgtcggaggagaagacagctggggaggtgaatctgtcttcctccaactcccca
tatgactacacaaaagtgacctacagccaggaagatgtggacaagctgttacgactgacg
cattacaacatctgcaacaaccaggatcggctgcgggaggccatgcaccaggccgtgcag
cggcggagaaaccgcagacagtttaggcgggagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (1)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (3)   
   Pfam (3)   
All databases (76)   

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