KEGG   Rattus norvegicus (rat): 311372
Entry
311372            CDS       T01003                                 
Symbol
Spg11
Name
(RefSeq) spatacsin
  KO
K19026  spatacsin
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05014  Amyotrophic lateral sclerosis
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    311372 (Spg11)
   05022 Pathways of neurodegeneration - multiple diseases
    311372 (Spg11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:rno03400]
    311372 (Spg11)
DNA repair and recombination proteins [BR:rno03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Other HR factors
     311372 (Spg11)
SSDB
Motif
Pfam: Spatacsin_C
Other DBs
NCBI-GeneID: 311372
NCBI-ProteinID: NP_001402853
RGD: 1562529
Ensembl: ENSRNOG00000021954
Position
3:complement(129453118..129526469)
AA seq 2428 aa
MAAKPGPGSAASPGCAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSL
QVLSLAPGSRGGSSCRLQGPFRQFLWEESQNSTSADKPRVLVAREDCGLLIYEFDLRDGR
CDAALLHSCCGRTLQKLTEDQGVSISFKSLRILSFDNSTSLLLINECLVVRVVFPGRESG
IGVLGCLSLPLPAQAVDTIIDVQLCKRFLFLLSTLGWIHIFDTVKGMHVARVDLALPRED
SEQQEPASISSFMSLKVSRDLDVLLLVSSSSTAVALNLHLYFRLHPGHLLCEGTLQDLPI
EGPTGIDEDDLVNSAHNMKLTKVSFQVDRSWRAQLASLNESVRSSEPELSCYPPWFQGAL
CLESLESGNHSPIVPNHVFIPGDVPSGQYAFPQKEHSKTSEPRPWRTMHLSEQEQPTELT
CLSVTGFTALFIQAVGTTSCTVVLWDLETQSMQCFSLSQKCTPVDISGDQQLCLALTENG
LSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFF
LKSKENLLTPSSKSPAPDQQQHFSSQLYLRQVEEMTPALDLLCSAIRESDSETQSKHFAE
QLLHLTLSFLNKQMRELFDHTEELDEHLQKGAAILTSYINELRTFMIKFPWKPGDAIDES
DENEEVLTVKEGQVWEELRSEEVIADAILNNRIPEAQTFFRITGHSAQRLEELVRIGLDL
AFDSLKKNSVEEASRLLRNMGFSVEDELLKISFYTTDKNIRDFLVEILKEKECFSEKERR
TVDFVHQAERLYSGHFQENAPMQAFPRYWIKEQDCFKHKSVLDTFLKCDTKDEFTKQDHR
IALNWAHWWDRQTQECILLPRISSEEYKAHSPEALWRHLTARHDWSSISLWMEEFQAQET
VSPQQSKWPPLSAAVIEQNTCCSRHMRNAILDQLARCGIFLASELEDFELLLLRLSRIGG
VMQDALPVQSYRSSAGCNFDSQVILYCLEHGLQHLLYVYLDYYKLSPGNCPFLEKKELHE
AHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQISIPTNQASVSSMLLEGHTLLALATTM
YAPGGVSQVIQHEDSENCLKKVDPQLLKMALTPYPKLKAALFPQCTAPSILPSDITLYHL
IQSLPPFDPSRLFGWQSANTLAIGDAAGQLPHFSSPDLVSKYAVVEQLSYTYYLHHGRPS
FAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFHNPSVGAACVCFLELLGLSSLKLR
VDLKMANVVLGSRRRNEDAHPSFIRESLAEKLSKLADGDRATTEELLVLLEEGVWDSIEQ
QGFNRLSSESSSQWSLVLQFCMLHDMKLSVSYLRECAKANDWLQFLVHSQLHNYHPEEVE
TLLQYFSPVLQSHLKLASEKLSSGSISKDDSCLQELQKNKETSDFFEILHRCSDESASWC
WLLAEAVRHRVPILSVLASCIQGASAVPCLCVWIVTSVEDKVAAEAIEHIQISVEDHHWS
LEDLSIIWRTVLTRRKIHTLIRGFRLFIKDSPLLLIMEMYELCVFFKNYGKAKVKLVEFQ
KSLEMLDTVATRVLPVIPATWMREQVCFLLKLMPQQCETQYELQKVLQLFVGMEQLFSDG
PDVQKLYRLSQVLKDTPITISPAVISSYSTESLQRECRSILEKLKADGQFAVARRVAELA
SLPVDGLVIEQLTQEMQMLTHTQQWSLKQARLDFWRKCHENFKKNSVSNRAASSFFSSQA
PEASEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEELEKQIWLCRIAQHTCGGAEE
ETKPSLSQHKLAPAELSSDSSASEFSFSKLAALNTSKYLDLNGLPSKEMCENTLEHREQE
SLNTLIGQLLDGGCVHEASRVCRYFRVYSQDLVLLLHCRALASAEASMEDLHSEIRALLS
NATLPEDLESPGVPLRKVHSTSSLDSLSFAMVPPTDEVARSLQTLISRCLHGKDYCRQVL
CLYELAKELGCSYGDVATRDSEAMLRAILASQRPDRCRQAQVFINTQGLEPDTVAELVAE
EVTRELLTPSEGAGEKQPFNLAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHGELSCT
TELLILAHHCFTCACYMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYI
FDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCHPGDSEKHNMIALCFSMCREIGENH
EAAACIQLKLIESQPWEESLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLT
KLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAEVLYQQV
ILKGDFSYLEEFKQQKLLKPNIFEDISKKYKQHQPTDRVTENLKKLLSYCEDIYLYYKLA
YEHKFFEIVNMLLKDPQTGCCLKDMLAG
NT seq 7287 nt   +upstreamnt  +downstreamnt
atggctgccaagccagggcccggaagtgctgcctcccccggctgtgccggcgccatggag
cgagttctacccatgctgctggtgcggatccctgccgaggagacggcgcagctgggaccg
cgggcgcagctgcaccgagagctggaggccctggggagcctgacggctgcgggcagtctc
caagtgctttccttggcgccgggcagtaggggtggaagcagctgccgcctccaaggcccc
tttaggcagttcctgtgggaggagtctcagaacagcacatcagcagacaagcccagagtg
cttgttgctcgagaagattgtgggctgctcatatatgaatttgacttgagagatggaaga
tgtgacgcagccttactacacagctgttgtgggaggaccctgcagaagctcactgaagat
caaggtgtcagcatttccttcaagtctttgaggattctgtcatttgacaacagcacgtcc
ttactgctcatcaatgagtgtctcgtcgtacgtgtcgtgtttccggggagagaatctggg
attggagtgctgggctgcctctcactgcccttgcctgcacaggcagtggacacgataatt
gacgtgcagctctgcaagaggtttcttttccttctgagtacattaggctggatccatatt
tttgacactgtaaagggcatgcatgtagcccgcgtggacttggctcttccccgagaagat
tctgagcagcaggagcctgccagcatttcttcctttatgtcactgaaagtgtctcgggac
ttagatgttttgctactcgtcagctcgtccagtactgcagttgctcttaaccttcacttg
tatttcaggctacacccagggcacctgctgtgtgaaggaactctgcaagacctccctatt
gaagggcctacaggaatagatgaagatgaccttgttaattctgcccacaacatgaaactg
accaaggtgtccttccaagttgataggtcctggagagcccagctggcatcactgaatgaa
tctgtgaggagctcagaaccagagctttcctgctatcctccgtggttccagggtgctttg
tgtttggagtccctggaatctggtaaccactcccccattgtgccaaaccacgttttcatt
ccaggggatgtcccgagtggccagtatgcttttcctcagaaggagcacagcaagaccagt
gagccaaggccgtggaggacaatgcacctgagtgaacaagagcagcccacagagctcacg
tgtctgtctgtgacgggatttacggccctgtttattcaggcagtaggaacgaccagctgc
accgtcgtcctctgggacttggagacccagagcatgcagtgtttttctctcagccagaag
tgtactcctgtagacatcagcggagaccagcagctgtgccttgctttgacagagaacggc
ctgtctctgattttgtttggtttaactcaagaggagtttctgaacagactgatgatccat
ggcagtgccagcactgtggactccctttgtcatctcaacggttggggacggtgctcaatc
cccatccacgctctagaggctggcatagaaaatcgtcagctggacacggtagatttcttc
ctgaagagcaaggaaaatcttcttactccatcttcaaaatctcctgcccctgatcagcag
cagcacttctcctcccagctctacctaaggcaggtggaagagatgaccccagccctggac
ttactctgctcagcaattagagaaagcgactccgaaacccaaagcaagcactttgcagag
cagctgcttcacctcacactgtctttccttaacaagcaaatgagggagctttttgatcac
actgaagagctagatgagcatttacagaaaggagcagccattttgaccagctacatcaat
gaacttcggacttttatgataaagtttccttggaagccaggagatgccatagatgaatct
gatgaaaatgaagaggtcctcacagtgaaagaaggccaggtttgggaggaactccgctct
gaggaagttattgctgatgccattttaaataacagaataccagaggcacaaactttcttc
aggattactggtcattccgctcaacgacttgaggaactggttaggataggcctagatttg
gcatttgacagtttaaaaaagaacagcgtggaggaggcctccaggctcttgaggaacatg
ggcttcagtgtggaagacgagctgcttaagataagcttttatacgactgataaaaacata
cgggactttttggttgaaattttaaaagaaaaggaatgtttttctgaaaaagaaagaaga
actgtggactttgtccatcaagctgaaaggctttactcaggacacttccaggaaaatgcg
ccgatgcaggcttttcccaggtattggataaaggaacaggactgtttcaaacacaaatct
gtcttggacacgttcctcaaatgtgatacaaaagatgagtttaccaaacaggaccataga
attgcactgaattgggctcactggtgggatcggcaaacacaggagtgtatccttctcccc
agaataagttcagaagaatataaagcacattccccagaagccctgtggagacacctcaca
gctcgccatgactggtcaagcatcagcttgtggatggaagaatttcaggcccaggaaact
gtgtcacctcagcagagcaagtggcctcctctgagtgctgccgtcatcgagcagaacact
tgctgcagcaggcacatgaggaacgcgatcttagaccagctggccagatgtggcattttt
cttgcatctgagctggaagactttgaacttctcctcctgagactgagccggattgggggt
gtaatgcaggatgccctccccgtgcagagctacagatcctcggcagggtgcaactttgat
tcccaagtcatcctctactgtttagagcacggcctgcagcatcttctctacgtctacctt
gactattacaaacttagccctggaaattgtccctttttggaaaagaaagaactacatgaa
gctcacccttggcttgaatttttggttcagtgtcggcaagtttccagtaacttgacagat
cccaaactgatctttcaggccagtcttgcaaatgctcagatttcgattcccaccaatcaa
gccagtgtgagcagcatgctgttggaaggacacaccctcttggctcttgctaccaccatg
tatgctcctgggggcgtcagccaggtcattcagcatgaagacagcgagaactgtttgaag
aaagtggacccccagctactgaagatggccttaacgccttacccaaagctcaaagccgcg
ctcttccctcagtgcactgctcctagtattctgccctctgacattacactctaccacctc
atccagtccttaccaccctttgatcccagcagactgtttggctggcagtctgccaacact
ctagctatcggagatgcggccggtcagctcccacacttctccagtcctgacctggtgagt
aaatacgccgtggtggagcagctgagctacacgtattacttacatcacggacgcccatcc
ttcgccttcggcacctttctggtccaggagttaatcaagagtaagactcccaagcagctg
atccagcaagtaggcaaggaggcctataccttagggctctcctccttccacaacccttcg
gtaggggccgcctgtgtctgcttcttagaattgcttggcctcagcagcctcaagctcaga
gttgacctgaaaatggcaaacgtagttctgggctccaggcgtagaaatgaagatgcacat
cccagcttcatcagagagtctctggctgagaagctgtctaagcttgctgacggtgacagg
gcaaccacagaagagctgctcgttctcttggaggaaggcgtgtgggacagcattgagcag
cagggctttaacaggttgtccagcgaatccagcagccagtggtcattagtgttacagttc
tgcatgctccatgatatgaaactgagcgtgtcctaccttagagaatgtgccaaagcaaat
gattggctgcagtttctggttcacagccagctccataactaccacccagaagaggtggaa
accctgcttcagtatttcagtcctgtccttcagagtcacttgaagctggcttctgagaaa
ctgtcatcagggtccatctctaaggacgacagctgcctccaggaactccagaaaaacaaa
gaaacaagtgatttctttgaaattctccaccggtgctcggatgagtcagcttcctggtgc
tggctcctggctgaagcagtgagacatcgggttcccatcctcagtgtcctggcctcgtgt
atccagggtgccagtgctgtcccctgtctctgtgtttggattgtcacctctgtggaggac
aaggttgcagctgaagcaatagaacacattcagatctctgtagaggaccatcattggagc
ctcgaggacctgtccattatctggagaactgtattgacaagacggaagatccacactctc
atccgaggcttccggcttttcattaaggattccccacttctcttgattatggaaatgtat
gaactgtgtgtgttcttcaagaactacggaaaagccaaagttaagcttgtggagttccag
aaaagccttgaaatgcttgacacagtggctactcgggtccttcctgtcatacctgccacg
tggatgagggagcaggtgtgcttccttttgaaacttatgccacagcagtgcgagacacag
tatgagctgcagaaagtcctccaactgtttgtcgggatggagcagctcttctccgatggg
ccagacgtgcagaagctgtatcggctcagccaagtactgaaggacacacctatcaccatc
agccctgcagtcatttccagctacagcactgagagtttgcagcgtgagtgtagatctatt
ttggagaagctaaaggcagatggacagtttgctgtggccaggagagtggcagaattagca
tccctgcctgtggacggcttggtgattgaacagttaacgcaggaaatgcaaatgctaaca
cacacccagcagtggtccctgaaacaagcaagacttgacttctggagaaaatgccatgaa
aattttaagaaaaactctgtttcaaacagagcagcctcttccttcttctccagccaagcc
ccggaggcgagtgagcaccctgctgagcagggcagccttgaggagcgccatctgctgctc
actctggcgggccactggcttgcccaagaagagccagttcccgtggaggaactggaggag
ctggagaaacagatttggctctgccgcatcgcccagcacacatgtggaggggctgaagaa
gaaaccaagcccagcctctcgcaacacaagttggcccctgctgaactttcttctgatagc
tcagccagtgagttctccttctccaagcttgctgctttgaacacatccaaatacttagac
cttaatggtcttccatccaaggagatgtgtgagaacacactggaacacagagagcaggag
tcactgaacactttgattgggcagctgctggatggtggctgtgtgcatgaagcgagcaga
gtgtgccggtatttccgtgtctatagtcaggatctagtgctgctgctgcactgcagagcc
ttggcctccgcagaggccagcatggaagatctgcactcagagatccgtgccctcctctca
aatgccacactacctgaggacctggagagccctggcgtccctcttcggaaagtccatagc
acttcgagtttggacagtctgtcatttgcgatggtaccacctactgatgaagtggccagg
agtctccaaactctcataagcaggtgcctccatgggaaggattactgtcggcaggtcctc
tgtctgtatgaacttgccaaggagttgggctgttcctatggagatgttgctaccagggac
agtgaagccatgctccgagcaatcttggcttctcagcggcctgaccgatgcagacaagcc
caggtcttcatcaacacccagggccttgaaccagacactgtggctgaacttgtggctgaa
gaggtgacacgagagctactgaccccatcagagggagcaggagaaaagcagcctttcaac
ctagcagaggaaagccagacatttcttcagctaactgctttgtgtcaagaccgtacattg
gtaggcatgaagttgttggacaagattccatctgtcccccatggggagctgtcatgcacc
acagagctcctgatcctggcccatcactgctttacctgtgcgtgttacatggagggcatc
atcagagtcctacaggctgcccggatgcttacagataaccacttggctcccaatgaggag
tatggattggtggtacgcctcctcactggcattggacggtacaatgagatgacgtacata
ttcgacttgctgcatcaaaagcattattttgaagttctgatgaggaagaagctagatcca
accggcaccctgaaaacagccctactagactacatcaaacgctgccaccctggagacagt
gaaaagcacaatatgatcgccctgtgcttcagcatgtgtcgggagataggagagaaccac
gaggccgcagcctgcatccaactgaagctgatcgaatctcagccctgggaggaaagtctc
aaggatggagcccaactaaaacagctcctgcttaaagccctgactttgatgctggacgca
gcagagagttacgcaaaggactcctgtgtgcggcaggccctgcattgtaaccggctcacc
aagttgataacactacagattcactttctcaacagtggccagaacacaatgctcatcaac
ttgggccatcagaagctaatggactgtatcatgaccctacctcggttctaccaggcttct
attgtagctgaggcctatgactttgttcctgattgggctgaagtactctaccaacaagtg
attcttaaaggagactttagttacttggaagaatttaagcagcagaagttactaaaaccc
aatatatttgaagacatttccaaaaaatataaacaacaccagcctactgacagggtcaca
gaaaacctgaagaagttactttcatattgtgaagacatctacctgtattacaagttggca
tatgaacacaagttttttgaaattgtaaatatgcttctgaaggatcctcaaacaggatgc
tgtcttaaagatatgctcgcgggttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (1)   
   Pfam (1)   
All databases (23)   

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