KEGG   Rattus norvegicus (rat): 314641
Entry
314641            CDS       T01003                                 
Symbol
Pip5k1c
Name
(RefSeq) phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform c
  KO
K00889  1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00562  Inositol phosphate metabolism
rno01100  Metabolic pathways
rno04070  Phosphatidylinositol signaling system
rno04072  Phospholipase D signaling pathway
rno04144  Endocytosis
rno04510  Focal adhesion
rno04666  Fc gamma R-mediated phagocytosis
rno04810  Regulation of actin cytoskeleton
rno05135  Yersinia infection
rno05231  Choline metabolism in cancer
Module
rno_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    314641 (Pip5k1c)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    314641 (Pip5k1c)
   04072 Phospholipase D signaling pathway
    314641 (Pip5k1c)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    314641 (Pip5k1c)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    314641 (Pip5k1c)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    314641 (Pip5k1c)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    314641 (Pip5k1c)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    314641 (Pip5k1c)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    314641 (Pip5k1c)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    314641 (Pip5k1c)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     314641 (Pip5k1c)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    314641 (Pip5k1c)
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    314641 (Pip5k1c)
 Endosome - Golgi transport
  Others
   Others
    314641 (Pip5k1c)
SSDB
Motif
Pfam: PIP5K Toxin_33
Other DBs
NCBI-GeneID: 314641
NCBI-ProteinID: NP_001009967
RGD: 1309938
Ensembl: ENSRNOG00000020577
UniProt: Q5I6B8 Q3MID5
Position
7:complement(9048135..9076751)
AA seq 688 aa
MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAILAEAPLVTGQPGPGHGKKLGH
RGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGS
NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVT
SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNN
VLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVK
TLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTAMES
IQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDG
DTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIP
SEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPS
DTSEQPRYRRRTQSSGQDGRPQEELHAEDLQKITVQVEPVCGVGVVVPKEQGAGVEVPPS
GASAAATVEVDAASQASEPASQASDEEDAPSTDIYFFAHGRYWLFSPRRRRLRAVTPSHT
GAPTDERSWVYSPLHYSARPASDGESDT
NT seq 2067 nt   +upstreamnt  +downstreamnt
atggagctagaggtgccggacgaggcagagagcgccgaagcaggggccgtgacagcggag
gcggcctggtctgcggagagtggggcggcggcaggtatgacccagaagaaggctatcctt
gcagaggccccgttggtgacagggcagccaggccctggccatgggaagaagctgggccat
cgaggcgtggatgcgtctggagagactacgtataagaagaccacctcgtccaccctgaag
ggtgccatccaactggggattgggtacacggtgggcaacctcagctctaagccagaacgc
gatgtgctcatgcaggacttctatgtggtggagagcatcttctttcccagcgaagggagc
aaccttacccccgcccaccacttccaggatttccgtttcaagacctatgcacctgttgcc
ttccgttacttccgggagctctttggtatccgtccggacgattacttgtactcactctgc
aacgagccactcattgagctgtccaacccgggtgccagtggctccgtcttctacgtcacc
agcgatgacgagttcatcattaagactgtcatgcacaaggaggcggagttcctgcagaaa
ctgctgcctggctactatatgaacctcaaccagaacccccggaccttgctgcccaagttc
tatgggctgtactgtgtgcagtccggcggcaagaacattcgagtggtggtcatgaacaat
gtgctgccccgtgtcgtcaagatgcacctcaagttcgacctcaagggctccacgtacaag
cgcagggccagcaagaaggagaaggagaagagcctgcccacctacaaggacctggacttc
atgcaggacatgccagaggggctgctactggactctgacacctttggcgccctggtcaag
acgctgcagcgagactgcctggtgttggagagcttcaagataatggactacagcctgctg
ctgggtgtgcacaacattgaccagcaggagcgggagcgccaggccgagggcgcccagagc
aaggctgacgagaagcggccggtggcccagaaggccctctactccacagccatggagtcc
attcagggcggagctgcccgtggggaggccattgagacagatgacacgatgggtgggatc
ccagccgtgaatgggcgtggggagcgcttgctcctacacatcggaatcattgacattctg
cagtcctacaggttcatcaagaagttagaacacacctggaaggccctcgtccacgatggg
gataccgtctcagtccaccggcccagcttctatgccgagcgcttcttcaagttcatgagc
agcacggtcttccggaagagttcctccctcaagtcctctccatctaagaaagggcgtggc
gccctgctcgcagtcaagcccctggggcccaccgcagccttctcagctagccagatcccc
agtgagagagaggatgtgcagtacgacctgcggggggcccgcagctaccccacgctggag
gatgaaggccggcctgacctcctgccctgcaccccaccgtcctttgaggaagccaccaca
gcctctatcgccaccaccctgtcatccacctccctctccatcccagagcggtccccttca
gacacatcagagcagccccggtacaggcggcgtacgcagtcttcaggccaggatggccgg
ccccaggaggagctgcatgcggaagacctgcagaagataactgtgcaggtggagccagtg
tgtggtgtgggggttgtcgtccccaaggagcagggtgcaggagtggaggttcccccatct
ggggcatcggcagcagccacggtggaagtagacgctgccagccaggcctcagagcccgcc
agccaagcctctgatgaggaagatgcgccttccacagacatctattttttcgcccacggg
agatactggcttttctctccccgtcgtcgccgactgcgggccgtgacaccaagccacaca
ggcgctcccaccgacgagaggagctgggtgtactccccgcttcactatagcgcacggccc
gcctccgacggcgagagcgacacataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (20)   
   RefSeq(nuc) (6)   
   GenBank (7)   
   EMBL (7)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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