KEGG   Rattus norvegicus (rat): 353498
Entry
353498            CDS       T01003                                 
Symbol
Cyp11b3
Name
(RefSeq) cytochrome P450, family 11, subfamily b, polypeptide 3
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno01100  Metabolic pathways
rno04927  Cortisol synthesis and secretion
rno04934  Cushing syndrome
Module
rno_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    353498 (Cyp11b3)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    353498 (Cyp11b3)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    353498 (Cyp11b3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    353498 (Cyp11b3)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     353498 (Cyp11b3)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP11 family
   353498 (Cyp11b3)
SSDB
Motif
Pfam: p450 Ints3_N
Other DBs
NCBI-GeneID: 353498
NCBI-ProteinID: NP_861545
RGD: 727886
UniProt: Q64539
Position
7:complement(108689319..108694808)
AA seq 498 aa
MALRVTADVWARPWQCLHRTRALGSTATQAPKTLKPFEAIPQYSRNKWLKMIQILREQSQ
ENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPRRMTLESWVAHRE
LRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAVQSFVPFVDVVARDFVENLKKRMLENVH
GSMSMDIQSNVFNYTMEASHFVISGERLGLTGHDLNPESLKFIHALHSMFKSTTQLMFLP
KNLTRWTSTQVWKGHFESWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSMD
AIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIAANPQKAMSDL
PLLRAALKETLRLYPIGSSLERIVDSDLVLQNYHVPAGTLVIIYLYSMGRNPAVFPRPER
YMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAY
RFVLMPNPRLVLTIRPVS
NT seq 1497 nt   +upstreamnt  +downstreamnt
atggctctcagggtgacagcagatgtgtgggcaagaccctggcagtgcctgcacaggacg
agggcactgggcagtacggcaacacaggcccccaagacactgaagccctttgaagccata
ccacaatactccaggaacaagtggctgaagatgatacagatcctgagggagcagagccaa
gagaacctacacctggagatgcaccaggccttccaggaactagggcccattttcaggcac
agtgcagggggagcacagattgtgtctgtgatgctgcctgaggacgctgagaagctgcac
caggtggagagtatcctcccgcgtcggatgacgctggagtcgtgggtggcccacagagaa
ctccgtggcctgagacgtggtgtgttcttgctaaatggggcagactggcgcttcaaccga
ctgcagctgaatccaaatatgctgtcaccaaaagccgttcaatcttttgtcccctttgtg
gatgtggtagcaagggactttgtggaaaacctgaagaagagaatgctggagaatgttcat
ggaagcatgtctatggacattcagtccaatgtgttcaactataccatggaagccagccat
tttgttatttccggagagcgactgggcctcacaggccatgacctgaaccctgagagcctg
aagttcattcatgctctgcactcaatgttcaagtccaccacacagctcatgttcttaccc
aagaacttgactcgttggacaagcacccaggtgtggaaaggacactttgagtcctgggat
atcatctctgagtatgtcacaaaatgtatcaagaatgtgtatcgcgaactggcagagggt
cgccaacagtcctggagtgtcatatccgagatggtagcacagagtactctgtcaatggat
gccatccatgccaactcaatggaacttattgctggaagtgttgacacgacagcaatctcc
ttggtaatgaccctttttgagctggctcggaacccagatgttcagcaggccctgcggcag
gagagcctggcagctgaggccagcatcgctgctaatccccagaaggccatgtcagacttg
cccttgctgcgggctgcccttaaagagaccttgaggctctaccccattggtagctctttg
gagagaatcgtagactcagacctggtgcttcagaactatcatgtccctgctgggacgttg
gtcataatttatctgtactccatgggccgaaaccctgcagtgttcccaagacctgagcgc
tacatgcctcagcgctggctggagaggaaaaggagtttccagcatctggccttcggcttt
ggggtgcgccagtgcctggggcggcgcctggcagaggtggaggtgttgctcctgcttcac
catatgctgaaaatcttccaagtcgagacactgaggcaagaggatgtgcagatggcctat
cgctttgttttgatgcccaaccctagactcgtcctcactatccggcctgtgagctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (20)   
   KEGG COMPOUND (20)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (52)   

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