KEGG   Rattus norvegicus (rat): 361213
Entry
361213            CDS       T01003                                 
Symbol
Sptlc1
Name
(RefSeq) serine palmitoyltransferase 1
  KO
K00654  serine palmitoyltransferase [EC:2.3.1.50]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00600  Sphingolipid metabolism
rno01100  Metabolic pathways
rno04071  Sphingolipid signaling pathway
Module
rno_M00094  Ceramide biosynthesis
rno_M00099  Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    361213 (Sptlc1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    361213 (Sptlc1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:rno01007]
    361213 (Sptlc1)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.50  serine C-palmitoyltransferase
     361213 (Sptlc1)
Amino acid related enzymes [BR:rno01007]
 Aminotransferase (transaminase)
  Class II
   361213 (Sptlc1)
SSDB
Motif
Pfam: Aminotran_1_2 Cys_Met_Meta_PP
Other DBs
NCBI-GeneID: 361213
NCBI-ProteinID: NP_001101876
RGD: 1307140
Ensembl: ENSRNOG00000010882
UniProt: D4A2H2
Position
17:12029189..12068234
AA seq 473 aa
MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEEL
IEEWQPEPLVPPVSRNHPALNYNIVSGPPTHNIVVNGKECVNFASFNFLGLLANPRVKAA
AFASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSK
RGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRR
FIVAEGLYMNTGTICPLPELVRLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDI
DLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENP
GIFAVLKKKCQTIHKSLQGVSGLKVVGESLCPALHLQLEESTGSRERDMKLLQEIVEQCM
NKGIALTQARYLDKEEKCLPPPSIRVVVTVEQTDEELQRAAATIREAAQAVLL
NT seq 1422 nt   +upstreamnt  +downstreamnt
atggcgacggtggcggagcagtgggtgctggtggagatggtgcaggcgctgtacgaggct
ccagcataccatctaattctggaaggaatcctcatactttggataatcagactcgttttc
tctaaaacttacaagttgcaggagcgttctgaccttacagccaaggaaaaggaagaactg
attgaagaatggcagccagagcccctcgtccccccggtctccaggaaccatcctgctctc
aactacaacatcgtctccggccctccaacccataacatcgtggtgaacggaaaagagtgt
gtcaactttgcctcctttaatttcctcgggttgctggccaaccctcgggttaaggctgcg
gcttttgcatcattaaagaagtacggcgtgggtacctgtggtcccagagggttttatggc
acatttgatgtccatctggatttggaagagcgcctggcaaagtttatgaagaccgaagaa
gctatcatttactcctatggcttctccaccatagccagtgcgattcctgcgtactctaag
agaggggacattgtttttgtggacagtgcagcctgctttgctatccagaaaggactacag
gcatcacgcagtgacattaagttattcaagcacaatgacgtagctgacctggagcgactg
ctaaaagaacaagagattgaagatcaaaagaatcctcgaaaggcccgtgtgactcggcga
ttcatcgtcgcggaaggattgtatatgaacactggaaccatctgccctcttccagaactg
gtgaggttaaagtataaatacaaagcaaggatcttcctggaggagagcctgtcgttcgga
gtccttggggagcatgggcgaggagtcaccgagcactatgggatcagtattgacgacatc
gaccttatcagtgctaacatggagaatgcgctcgcttctgttgggggcttctgctgtggc
cgctctttcgtggttgaccatcagcggctctctggccaaggatactgcttttcagcttca
ctgccccccctgctagccgctgccgccattgaggccctcaacatcatggaggagaaccca
gggatttttgcagttttaaagaaaaagtgccagaccatccacaagtccctacaaggggtt
tccggtttaaaagtggtgggggagtccctttgcccagcgcttcacctccagctggaagag
agcacgggctctcgggagagagatatgaagctgcttcaggagattgtagagcaatgcatg
aataagggcatcgcattgactcaggcacgctacttggacaaggaagagaagtgccttcct
cctccaagcatcagggttgtggtcaccgtggagcagacagacgaagagctgcagagggct
gcagccaccatcagggaggcggcccaggctgtgcttttgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (30)   

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