KEGG   Rattus norvegicus (rat): 361267
Entry
361267            CDS       T01003                                 
Symbol
Akr1c15
Name
(RefSeq) aldo-keto reductase family 1 member C15
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00140  Steroid hormone biosynthesis
rno00590  Arachidonic acid metabolism
rno00790  Folate biosynthesis
rno01100  Metabolic pathways
rno04913  Ovarian steroidogenesis
rno05208  Chemical carcinogenesis - reactive oxygen species
Module
rno_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
rno_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    361267 (Akr1c15)
   00590 Arachidonic acid metabolism
    361267 (Akr1c15)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    361267 (Akr1c15)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    361267 (Akr1c15)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    361267 (Akr1c15)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     361267 (Akr1c15)
    1.1.1.188  prostaglandin-F synthase
     361267 (Akr1c15)
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     361267 (Akr1c15)
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     361267 (Akr1c15)
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 361267
NCBI-ProteinID: NP_001103370
RGD: 1307514
Ensembl: ENSRNOG00000021735
UniProt: D3ZF77 A0A387KC71
Position
17:complement(71091398..71117985)
AA seq 324 aa
MDLKHSRSVKLNDGNLMPVLGFGTFASKEIPKSKAAEATKVAIDVGFRHIDAAYFYQNEE
EVGQALRDKMADGTVKREDLFYTTKIWITFLRPELVRQCLERSLKKLGLDYVDLCIIHIP
IAMKPGEELLPKDANGKFIFDTVDIRDTWEALEKCKDAGLSKSIGVSNFNHKQLELILNK
PRLKYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSHRDSSWVSSDSPYLLEDP
VLMTIAKKHNQTPGQVALRYQLQRGVVVLAKSFNEKRIKENFQVFDFELTPEDMKTIDSL
NRNFRYSQMAFALDHPDYPFLEEY
NT seq 975 nt   +upstreamnt  +downstreamnt
atggatctcaaacatagtcgttcagtgaagctgaatgatggaaacttgatgccagtgctt
gggtttggcacatttgcttctaaagagattccaaagagcaaggctgccgaggccacaaaa
gtagccattgatgtgggtttccgtcacatagatgcagcatacttctatcaaaatgaggaa
gaagttggacaggccctccgagacaagatggctgatgggactgtgaagagggaggattta
ttctacaccaccaagatttggattactttccttagaccagagttggtacgtcagtgcctg
gagagatcgctgaagaaacttgggctggattatgtggatctctgcattattcatataccg
attgctatgaagcctggagaggaacttctgccaaaggatgctaatggaaaattcattttt
gatacagtggacattcgtgatacttgggaggcactggagaagtgtaaggacgcaggtcta
tccaagtctataggggtgtccaatttcaaccacaaacagctggaactgattctgaacaaa
ccaaggttgaaatacaaacccacctgcaaccaggtagaatgtcacccgtatctcaaccag
agcaaactcctggagttctgcaagtccaaagacattgttctcgttgcctatagtgctctg
ggatcccacagagactcaagctgggtcagcagtgatagcccatacctcctggaggatcct
gtcttaatgaccattgccaagaaacacaaccaaactccaggccaggttgccctgcgctac
caactgcagaggggggtggtggttctggccaagagcttcaatgagaagagaatcaaagag
aacttccaggtgtttgactttgaattgaccccagaggacatgaaaacaattgacagcctc
aacagaaattttcgatattctcaaatggcatttgctctggatcaccctgattatccattt
ttggaagaatattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (25)   
   KEGG COMPOUND (25)   
Chemical reaction (19)   
   KEGG ENZYME (4)   
   KEGG REACTION (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (1)   
   Pfam (1)   
All databases (75)   

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