KEGG   Rattus norvegicus (rat): 361472
Entry
361472            CDS       T01003                                 
Symbol
Mthfd1l
Name
(RefSeq) monofunctional C1-tetrahydrofolate synthase, mitochondrial
  KO
K13402  monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00670  One carbon pool by folate
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
Module
rno_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    361472 (Mthfd1l)
Enzymes [BR:rno01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     361472 (Mthfd1l)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 361472
NCBI-ProteinID: NP_001101932
RGD: 1307311
Ensembl: ENSRNOG00000019582
UniProt: B2GUZ3
Position
1:42849424..43038313
AA seq 977 aa
MSARLPLLLRQLGHQQLPPGPACRLRELCRSGSRSSSSGGGDPEGLRGRRLQDGQAFISH
SPGSPEDPGMDSIVRDVIHNSKEVLNLLQEKNPAFKPVLAVIQAGDDHLMQNVNQNLAKE
AGLDITHICLPPDSGEDEIIDEILKINEDPRVHGLALQISEDSLCNKVLNALKPEKDVDG
VTDVNLGKLVRGDAPECFVSPLARAAVELIEKSGITLDGKKVLVIGAHGPLEAALQCLFQ
RKGSMTMSSPWITPQLQDKLREADIVVLGSPKPDEIPAAWIPSGATMLNCFHDFLSGKLR
GGSPGVPMNRLIADESVSLLAAALRVQNMVNSGRRWLREQQHRRWRLHCLKLQPLSPVPS
DIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSLLERLKDQTDGKYVLVAGIT
PTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEF
NLHLTGDIHAITAANNLLAAAIDTRIFHESTQTDKALYNRLVPLVNGVRKFSEIQLSRLK
KLGIHKTDPTALTEEEVRKFTRLNIDPSTITWQRVLDTNDRFLRKITIGQGSTEKGYSRQ
AQFDIAVASEIMAVLALTDSLADMKERLGRMVVASDKDGQPVTAEDLGVTGALTVLMKDA
IKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGME
KFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNL
QKQIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSAGGKGSVDL
ARAVREAANKRSRFRFLYDVQLPIVAKIRVIAQTVYGAKDIELSPEAQAKIDRYTQQGFG
NLPICMAKTHLSLSHEPDKKGVPRDFILPISDVRASIGAGFIYPLVGMMSTMPGLPTRPC
FYDIDLDTETEQVKGLF
NT seq 2934 nt   +upstreamnt  +downstreamnt
atgagtgcccgccttcctctcctgctacgccaactcggccaccagcagctgcccccgggc
ccggcgtgtcgcctccgtgagctgtgtcgatccggcagcagaagcagcagcagcggaggt
ggtgaccccgaggggttgcgcgggcggcggctgcaggatggccaagccttcatcagccat
agcccaggcagtccggaagaccccgggatggactcaatcgttagagacgtcattcacaat
tccaaagaagtgctgaacttgttgcaagaaaaaaaccctgcctttaagccagttcttgct
gtgattcaggcaggagatgaccacctgatgcagaatgtgaaccagaatttggccaaggag
gctggcctggacatcactcacatctgcctacctccagacagtggagaggatgagatcata
gatgaaatcctgaagattaatgaagaccctagagtgcatggccttgcccttcagatctct
gaagattcattgtgcaacaaagttctcaatgctttgaaaccggaaaaagatgtggacggg
gtgaccgatgtcaatctagggaagctggtgcgaggtgacgctcctgaatgttttgtttcg
cccttggccagagctgcagtagaactcattgagaaatcagggatcaccttggatggaaag
aaggtcttggtcataggggctcacgggcctctggaagctgccctgcaatgtcttttccag
agaaaaggatccatgacaatgagctccccgtggataacacctcagcttcaagacaagctt
cgagaggcagacattgtggtcttgggctcacctaagcccgacgaaattcctgctgcttgg
atcccgtcaggagccaccatgctcaattgcttccatgacttcttgtcagggaagctgaga
ggaggttctcctggggtccccatgaacagactcattgccgacgagagcgtgagtctcctt
gctgcagctctgcgggttcagaacatggtgaacagtggcaggagatggctccgagagcag
cagcatagaagatggcgactccactgcttgaaactgcagcctctctcccctgtgcccagt
gatattgagatctcacgaggacagactccaaaagcggtggatgtccttgccaaggagata
ggattgcttgcagatgaaattgaaatctacggcaagagcaaggccaaagtccgcttgtcc
ctgctggagaggttaaaggatcaaacagatggaaaatacgtcttggttgctgggatcaca
cccaccccacttggagaagggaagagcacagtcaccatcggactagtgcaggcactaact
gctcacctgaacgtcaactccttcgcctgtctgagacagccttcccagggacccactttt
ggagtgaaaggaggagctgcaggtggtggatatgctcaggtcattcccatggaggagttc
aaccttcacctgactggggacatccacgccatcactgccgctaataacttactggctgct
gccatcgacacgagaattttccatgagagcactcagacagacaaggctctatacaatcga
ctggttcccttagtgaatggtgtcagaaaattttcagaaattcaactttctcggctgaag
aaactggggatacataagactgatcccaccgctctgacagaagaggaagtgaggaagttc
acccgcctcaacattgacccctctaccatcacatggcagagagtattggacacgaatgac
cgatttctgagaaaaataactattgggcagggaagcacggagaaaggatattcccggcag
gcacagtttgacattgcagtggccagcgagatcatggccgtgctggccttgactgatagc
ctcgcagacatgaaagagcggctaggaagaatggtggtggccagtgacaaagatgggcag
cctgtgacagctgaggacttgggggtgacaggtgctctgacagttttaatgaaagacgcc
atcaagccaaatctaatgcagaccctggaaggaacacctgtgtttgtgcacgctggtccc
tttgctaatatcgctcatggcaactcgtcggtgttagctgataaaatcgcactaaaactg
gtcggcgaagaagggtttgtagtgactgaagctggctttggggctgatattgggatggag
aaattcttcaacatcaaatgccgagcttctggcctggtgcccaatgttgttgtcctggtg
gccaccgttcgagctctgaagatgcatggaggtgggccaagtgtaaccgctggggttcct
ctcaagaaagaatatacagaagagaacattcagctggtagctgatggctgctgcaaccta
cagaaacaaattcagatcgctcagctcttcggggtgcccgtggtggtggcactgaatgtc
ttcaagacggacacccgtgcagagattgacctggtgtgtgagctcgctaaacgggccggt
gcctttgatgcggtcccctgctatcactggtcagctggaggaaaagggtccgtggacttg
gctcgggctgtgagagaagctgcgaataagagaagccgcttccggttcctgtacgatgtt
cagcttcccatcgtggcaaagataagagtaattgcccagaccgtctatggagccaaggat
attgagctgtctcctgaggcacaggccaaaatcgaccgctatacgcaacagggttttgga
aatttgcccatctgcatggcaaagacccacctttctctgtctcatgaacctgacaaaaag
ggggtgccgagggacttcattctgcccatcagtgatgtccgagccagcatcggggctggg
ttcatttaccctttggtgggaatgatgagcacaatgccaggtctgcccacccgaccctgc
ttttacgatatagaccttgacacagaaacagagcaagttaaaggcttgttctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (29)   

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