KEGG   Rattus norvegicus (rat): 361802
Entry
361802            CDS       T01003                                 
Symbol
Hsd17b8
Name
(RefSeq) (3R)-3-hydroxyacyl-CoA dehydrogenase
  KO
K13370  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00061  Fatty acid biosynthesis
rno00140  Steroid hormone biosynthesis
rno01100  Metabolic pathways
rno01212  Fatty acid metabolism
Module
rno_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    361802 (Hsd17b8)
   00140 Steroid hormone biosynthesis
    361802 (Hsd17b8)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     361802 (Hsd17b8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     361802 (Hsd17b8)
SSDB
Motif
Pfam: adh_short_C2 adh_short KR Epimerase RNA_pol_Rpb1_4 RmlD_sub_bind
Other DBs
NCBI-GeneID: 361802
NCBI-ProteinID: NP_997694
RGD: 1303158
Ensembl: ENSRNOG00000000466
Vega: OTTRNOG00000001660
UniProt: Q6MGB5 A6JJG1
Position
20:4828571..4830635
AA seq 259 aa
MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGNPGSED
REPRGKHAAFQADVSEGPAAKRLLEQVQACFFRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIVGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLAS
EDSGYITGASVEVSGGLFM
NT seq 780 nt   +upstreamnt  +downstreamnt
atggcgtctcagctccggctccgttccgcgctggccctggtcacaggtgcgggtagcggc
atcggtcgtgcgatcagcgtgcgcctagcggcagagggcgccgcagtggccgcctgcgac
ctggacggggcagcggcacaggacacggtgcggctgctgggaaacccagggagcgaggac
agggagccgcgcgggaagcacgctgccttccaggcggacgtgtccgagggccccgcagcc
aaacgcctgctggagcaagtgcaggcctgcttttttcgcccgccatctgtcgttgtgtcc
tgtgcgggcatcacacgcgatgagtttctgctccacatgtcagaagaagactgggacaga
gtcatagctgtgaacctcaagggcaccttcctagtcactcaggctgccgcccaggcattg
gtgtccagtggcggtcgtggctccatcatcaacattagtagcatcgttggaaaggtgggg
aatattggacaaacaaattatgcgtcctccaaagcaggagtgattgggctcacccagact
gcagcccgggagcttggacgtcatggaattcgatgtaactcagtcctcccagggttcatt
gcaacgcccatgacccagaaaatgccagagaaagtgaaggacaaggtaactgcaatgatt
ccgttgggacacatgggggaccctgaggatgtagcagatgtggttgcgttcctggcatca
gaagacagtggatacatcacaggggcctccgtggaagtcagtggaggtcttttcatgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (9)   
   RefSeq(nuc) (7)   
   GenBank (1)   
   EMBL (1)   
Protein domain (6)   
   Pfam (6)   
All databases (62)   

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