KEGG   Rattus norvegicus (rat): 362096
Entry
362096            CDS       T01003                                 
Symbol
Setx
Name
(RefSeq) senataxin
  KO
K10706  senataxin [EC:5.6.2.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    362096 (Setx)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:rno03021]
    362096 (Setx)
Transcription machinery [BR:rno03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     362096 (Setx)
SSDB
Motif
Pfam: AAA_11 AAA_12 AAA_19 AAA_30 UvrD-helicase AAA_22 ResIII AAA_16 Helicase_RecD nSTAND3
Other DBs
NCBI-GeneID: 362096
NCBI-ProteinID: NP_001414209
RGD: 1565575
Ensembl: ENSRNOG00000013491
Position
3:32825771..32878740
AA seq 2647 aa
MSTCCWCTPGGSSTIDVLKCYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLISHFEKSMKAEAEDDDELYIVDNNGEEQLFDCSGQDFENRLRVPLFEILKY
PYLLLHERVNELCVEALCRMEQNNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNESYNREIQNIRNSSIRTKLEPEPHFDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILVSVIELHRNKKCLHLLWV
SSQQWVDAVVKCAKLPTTAFVRSCEKSPGSTPRGAAIMSSLALHSVPSNSVQLACVQLIR
GLLKEGYQLGQQTLCKRFWDKLNLFLRGNSSLGWQLTGQETHELQMCLKQIIRNIKIKMP
QYSTFGDTTSTFKTPPSFKEESEQIDRKPKKDIHSLGNCSPIPSKEPMKADSHRVPTKAS
ATEEEDFTQHYIDLNEEEPLPAELGVKQKSEALLSESAPEQVKISTEKSGKENSSYTAPN
STSRSGPEWGCDRGVIISTHSLTDSSSDFLEKVSTSNGDVPLKDGTVGKTSKPNFKVQKD
EICAKLSHVLKKQHRKSTLVNNIIDLEENAATSDLENCSGTDRGALKKDTIEHDVSSDSV
LNDDHEEQKSKNSSLFKKEIKSEKLDNSSFDDEDKLQIQEGHADDDLISFTEVTDTLVKK
TPCEGSVKVAVESRDNEMRVLTSNLEGQVPHDSNKALVAGPQVDLCNITLISQTTVIQFP
SGLSKQNSFQLQKDDKKCLTANHNRDATCHEQVIIISDSDDEDDADEQDEDKRCGIEGNI
EQSKVSRENDCSEQHDLVVNTSVEKKLVKEEETNCPIEFEDSESQVFEFESSSEVFSVWQ
DHKIDSKSSLQEDQKSCIAHVADSTNNNLGCGADSVSEEVVRNKEKGVKEHAEPHSSVSA
EGFCKIGVRKPKRKRCDKVTAEDPQRPSSSVRTEQLAEHRDLPERDLESADVDMAAPSSS
VERDSTVLQKKSTKPRPHSKPVRKVPASKATKKTHPDTRRGQTKSSCYISCRTSPAIVPP
KKFRQCPEPTSTVEKLGLKKGPRKAFELSQRSLECIVQLRDHGKTVGVVEAPKKTKLISP
QTLSIKNNKKLLTSQDLQFQRLMRSRSHQKRDFDYKNTDSVRAVSRVVQGSDVLAADSDE
PDNPGGSEPLAISSEKQLAKGTLSKAEVAEAASGPWGTGITCLVNQCESRVLSGGVPTDV
LMGSASEDPVGGGALTVQVGEVAAVRAAEPESSSDTDDDDNLFLTQHDPQDMDLCSQLEN
SKAIIVAHKDTVQREDSLSRPQLESLSIIKCKYKDCVETTKNQGEYCPKHSEAKAADDDV
FRKPGLPLSVARSSRPTTTKIFSSSSASRTANLSKSLESTTLQSALKNKSSGAQSNLKMT
PSSSLGSQKPVAEVKSLCNIFHFQTPSSSSKQSYKFTFSENRPASAASSVDILLPSQSIF
DTFIKEVLKWKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCAEYFNVFLPLIILNAFET
VAQEWLNSPNKENFYQLHLRKFPADYKKYWEFLIYLEESELAKQLHPKENDLVFLVPEKK
YMDRHSVQDRSHYYCGYVHKFRRTSVMRSGKTECSLCIQTQDNMPASVKELTKCIVISSL
VTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERIIAYLKDFNEDQKKAIE
TAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTESQRKGHSDENFNAKIKQNRV
LVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLDS
QVSHRMKKDLPSHIQEMLRRKEILDAQLDELSRQRALCRGGREMQRQELDEHIVIVSKER
QELASKIKEVQGRPQRAQNTIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA
GQSCEVETLSPLIHRCNKLVLVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQ
NMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRLTETIRCSSEWPFQPYLVFDVG
DGSEQRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEF
DKKGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILG
HLRTLMENQHWYELIQDAQKRGAIIKTCDPNYRHDAMKILKLKPVLQRSLTHPPATAPEA
PRPQGGLPSNRLDSGLATTSFAPSLYHTPSDTVTSKEPERPLLQDRLRDPRLLRRLDAEA
KGTFLRDPQPESPQLPGVVHLLGESGCPVLFQDLGFVVPPSTAIVAPLGSHRSPIQAEPR
PAHPAAAASTSKRKYSDPDAGLSHRREPRAFAGEQGRHGSVTHHALRSTDLDRRRLDDSS
AKRRRFL
NT seq 7944 nt   +upstreamnt  +downstreamnt
atgagcacatgctgctggtgcactccaggtggttcttccaccattgatgtcctgaagtgc
tatgcatctagcactggatcaagtgaatttcagacagctgatgaagacctctgctactgc
ttagagtgtgtggctgagtaccacagagccagagatgaggtgccattcttgcatgaggtt
ttatgggagctagaaaccttacgcctcataagtcactttgaaaagtccatgaaggcagaa
gctgaggatgacgacgagttatatatagtagacaacaatggagaggagcagctctttgac
tgtagtggccaagattttgaaaataggcttagagttcctctttttgaaatactgaagtac
ccttacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcgctttgtcgaatg
gaacaaaacaattgctcctttcaggtctttgacaaatacccaggcatctatttgtttttg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaacctggggaag
gtggacagagatgactattatgacttacaggaagttttaacttgcctttttaaagtcatt
gaattggggcttttggaaagtccagacatttacacatcttctgtgcttgaaaaaggcaaa
ctgatccttttgcctgcacacatgtatgatactaccaactacaaaaactattggctaggt
atttgcatgttgttgactattcttgaggagcaagccatggattcactgttgctgggttca
gacaaacaaaatgattttatgcaatcaattcttcacaccatggagaagcaatcggatgat
gacagcatggatcctttttggccagcgttacactgtttcatggtgattcttgatcgcctt
ggatctaaggtgtggggtcaacttattgaccctattgaagcatttcaaaccatcattaac
aacgagagctacaacagagagatccagaatatacggaacagctctataaggaccaaatta
gaaccggagccacattttgatgatatggtgacgtgcagccagattgtgtataactataat
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgtccagattattgtcca
aacatgtatgaagaaatggaaacgttagccaatgtacttcagtcagatattggtcaagat
atgcgtgttcataacagcacctttctgtggttcataccttttgttcagtcactcatggat
cttaaggatttgggtgtggcttacatagtagaagtaattcatcatctatactcagaagtc
aaagatgtcctcaaccagacagatgctgtgtgtgacaaagtcactgaattttttattctg
attttagtatcagtgattgaactgcatagaaataaaaaatgcttgcatctgctgtgggtg
agttctcagcagtgggtagatgctgttgtgaagtgtgccaagcttcctaccaccgcattt
gtacggagttgtgagaagtcacctggaagtacccccagaggagcagcaataatgtcgtcc
ttggcgttgcattcagtgccatcgaactctgtccagcttgcgtgtgtacagttgattagg
ggtctcctcaaagaaggttatcagcttggtcagcaaacactttgtaagcggttctgggat
aaacttaacttattcttacgaggaaattcgtctctgggttggcagttgactggtcaagaa
acccatgagttacaaatgtgtttgaaacaaataattagaaacataaaaatcaaaatgccc
caatatagcacttttggggatacaacttctacattcaaaacccctccatcttttaaagaa
gaaagtgaacaaatagacaggaagcctaaaaaagacattcattccttgggaaattgcagc
ccaataccttctaaagagccaatgaaagctgacagccatcgagtgccgacgaaagcaagt
gctacagaagaggaggacttcacgcagcactatattgacttgaatgaagaagagcctctg
ccggccgagctgggcgtgaagcagaaaagtgaggctcttctttctgaaagtgctccagag
caagttaaaataagcacagaaaagtctggaaaagaaaactcttcatatacagcaccaaat
agtacttcaagaagtggtccagaatgggggtgtgacagaggagtaattatatcaacacat
tcattgactgattctagcagcgattttctggaaaaggtatctacatcaaatggagatgtc
ccattaaaggatggcactgttggtaaaacttcaaaaccaaatttcaaagtacagaaagat
gaaatttgtgcaaagttatcacatgtcctaaagaagcaacacaggaaaagtactttggtc
aataacattattgatttagaggaaaatgcagccacgtctgaccttgagaactgttcagga
acagatagaggagctctaaaaaaagataccatcgaacatgatgtgtcttcagactctgtt
ctgaatgatgaccatgaagagcaaaaatctaaaaacagttcgttgttcaagaaagagata
aaaagtgagaagttggataatagttcttttgatgatgaagacaagcttcaaatccaggaa
ggccatgctgatgatgatttgatatcatttacagaagttactgatacactggtgaagaaa
actccatgcgagggttctgtaaaggtggcagttgaatcaagagataatgagatgagagtg
ctgacttctaacttggaaggacaggtgcctcatgacagcaacaaggctttggtagcaggt
cctcaggtagacctttgcaacataactttaatatctcaaaccactgttattcaatttccc
tcaggtttaagtaaacagaattcatttcagctacagaaagatgataaaaaatgtttgaca
gctaaccacaacagagatgccacctgccatgaacaagttattattatttcagattctgat
gatgaagatgatgctgatgagcaagatgaggataaacgttgtggtattgagggaaacatc
gaacagagcaaagtgtccagggagaatgactgttcagagcagcatgatttggtagttaac
accagtgtggaaaagaagcttgtgaaggaagaagaaacaaattgtcctatagaatttgag
gactctgaatctcaggtttttgagtttgaaagttcatctgaagtcttttcagtttggcaa
gatcataaaatagacagcaaaagttcccttcaagaggatcaaaagagctgtatagctcat
gtagctgatagtacaaacaataacttaggttgtggtgcagattctgtgtctgaagaggtt
gttagaaacaaagaaaagggtgttaaagagcatgcagaaccacacagtagtgtttctgct
gagggattttgtaaaattggagtaagaaaacctaagaggaaacgatgtgataaagttaca
gctgaagatcctcagcggccttcatcttctgtcagaactgaacaattggctgagcacaga
gatcttcctgaaagggacttagagagcgcagatgtggacatggcagctcccagttctagt
gttgagagagattctacggttttacagaagaagtctacaaagcctcgccctcactcaaaa
cctgttaggaaagttccagcttcaaaggctactaagaaaacccatccagataccagaaga
ggacagactaagagttcatgttatataagttgtagaacttctcctgctattgtaccacca
aagaagtttcgccagtgtccagagccaacttcgacagttgaaaaacttggtctgaaaaaa
ggtcctcggaaagcatttgagttgtcccagcggtctctggagtgtatagtccaattacgt
gaccacggcaagactgttggagtagttgaagcccccaaaaagactaaattaatttctcct
cagactctctctatcaaaaataataagaagcttctgacaagccaggatcttcaatttcaa
aggcttatgagatccagatcacaccaaaaacgagactttgattacaaaaatactgatagc
gtaagagcagtgtcacgcgtagtgcagggttcggatgtacttgcagcagactctgatgag
ccggataatcctggaggaagtgagccgcttgccatcagcagtgaaaagcagttagcgaaa
ggcacgctttccaaagcagaagtggcagaagctgcttctggtccttggggaacaggtata
acttgtcttgtgaaccagtgtgaatctcgagtgttaagtggaggagtgccaacagatgtg
ctgatgggctctgcttcagaggaccctgtgggtggaggtgctctcacagtgcaggttggg
gaggtggcagcagtgagagctgcagagccagagtccagtagtgatacagatgatgatgac
aatttattcctaacacaacatgaccctcaagatatggatctgtgctcacagttggaaaat
tctaaagccattattgtggctcataaagatacagttcagagagaagactctctaagtcgg
cctcagttggagtctttgagtatcataaagtgtaaatacaaagactgtgttgaaaccaca
aaaaaccagggtgaatactgcccaaaacattctgaagctaaagcggcagatgacgacgtg
tttcgtaaacctggcttgccactttctgtagccaggtcctcgagacctactactaccaag
atatttagctcaagcagtgcttcacgaactgccaatctttccaagtctttggaaagtacc
acacttcagtcagcactgaaaaataagtcaagtggagcacagtctaatttgaagatgaca
ccatcctcttccctggggtctcagaagccagtggctgaggtgaaaagtttatgcaatatt
ttccattttcagactccgagcagttccagcaaacagagttacaagtttacctttagtgag
aacaggcctgcgtcggctgcttcttcagtggacattctcttgccatcccagtctatcttt
gacaccttcattaaagaggtcttaaaatggaaataccaaatgtttttgaactttgataag
tgtggtgctccaacaagtctctgtcagtctatctcaagacctgtgcctgtccgatttcaa
gattgtgcagaatattttaatgtttttctacctttgataatattgaatgcttttgaaaca
gtggcacaggaatggctgaactctccaaataaagagaatttctatcagttgcatttacga
aaatttccagccgactataaaaaatattgggaatttctgatttacctggaggaatctgaa
ctcgctaaacagcttcatccaaaggaaaatgatctggtgtttttggttcctgagaagaaa
tacatggacaggcatagcgtgcaagatcgcagtcactattactgtggctatgttcataag
tttcgccgcacttcagtcatgcgcagtgggaaaaccgagtgctccttatgcatccagaca
caagataacatgccagccagtgttaaagagcttacaaagtgtatcgtaatcagttctctg
gtgactacacagaggaaactcaaagccatgtctctgttgagcggtcggaaccagttggcc
agagccgttctgaatccaaaccccatggacttctgtaccaaagatctactgactacaact
tctgaaagaattattgcctacttaaaagattttaatgaagaccagaagaaagccatagaa
actgcgtatgccatggtgaagcactcaccatcagttgccaaaatctgtctgattcatgga
ccacccggaacaggaaaatcaaaaacaattgtaggtctcttgtaccgcttactgacagag
agccagaggaagggccattcagatgaaaatttcaacgccaaaatcaagcaaaaccgagtc
cttgtgtgtgcaccttccaatgcagcggttgatgagcttatgaaaaaaattatcctcgaa
ttcaaagaaaaatgtaaagacaagaagaatcctttgggaaactgtggagatataaattta
gtaagactgggtccagaaaagtctattaatacagaggtcctaaaattcagtttggatagc
caagtcagccatagaatgaaaaaagacttgccttctcatattcaagaaatgcttagaaga
aaagaaattctagatgctcaacttgatgagctttctcgtcagcgagctctgtgtcgaggt
gggcgggagatgcagaggcaagaattagatgaacacattgtcatagtttcaaaagaaagg
caagaacttgcttcaaaaattaaagaggtgcagggacgcccacagagagcacagaatacc
atcatcttggagtcccatgtcatctgctgcacattgagcactagtggtggtttattgctt
gagtctgcttttcgagggcaagggggtgtccccttcagttgtgtcatcgtagatgaggcc
gggcagtcttgtgaggtggagacgctttctcctctcatccaccgctgcaataagctcgtc
ctggtgggggaccccaagcagctccctcccacagtcatctctatgaaagcacaggagtat
ggctatgaccagtcgatgatggcgcgattctgcaagctgctggaagagaatgtggagcag
aacatgattggcaggctgccggtgctacagctcaccattcagtacaggatgcatccagac
atatgtctcttcccttctaattacgtttataataaaaacctgaagacaaatagattgact
gaaaccattcgatgttcatcagagtggccatttcagccctacctcgtgtttgatgttgga
gatggttcagaacaacgggataatgactcatacataaatgttcaagaaataaagttggtg
atggaaataattaaacttattaaagagaaaagaaaagatatttccttccgaaatattggc
ataataactcattacaaggctcagaagacgatgatccagaaggatttggagaaagaattt
gataagaaaggacctgcagaagtggatacggtagatgccttccagggccggcagaaagac
tgcatcatcgttacctgtgtcagggcaagtgctgtgcaaggctcgataggattcctggca
agtttgcagagattgaatgtcaccattacacgagccaagtacagcctctttatccttgga
catttgaggactctgatggaaaatcaacattggtatgaactgattcaggatgctcagaag
cgtggggccattattaagacctgtgacccaaactatagacatgacgccatgaagatcctg
aaactgaagcctgtgctgcagaggagtctgacccatcccccagccactgctccggaggca
cccagacctcagggtggcttgcccagcaacagactggacagtggacttgccacaacatct
tttgctccttctttatatcacacaccctctgatactgttacttcaaaggaacctgaaagg
ccacttcttcaagaccgacttcgagatccacgactactcaggagattggatgctgaagcc
aaggggacattcctgagggatccacagcccgagagcccccagctccctggggtagtccat
ctcctgggagagtctggctgtcctgtgcttttccaggacctaggttttgttgtgccacca
tccactgccatcgttgctcctctgggcagccacaggtcgcctatacaggctgagccacga
cctgctcaccctgctgctgccgcctccacaagtaagaggaagtacagtgacccagatgct
gggctcagccacagaagagagcctagggcctttgctggagagcaggggaggcacggctct
gtgactcatcatgcgctgagaagcactgacttggacaggaggaggctggatgatagcagt
gccaagaggagacggtttctatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (32)   

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