KEGG   Rattus norvegicus (rat): 367901
Entry
367901            CDS       T01003                                 
Symbol
Btk
Name
(RefSeq) tyrosine-protein kinase BTK
  KO
K07370  Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04064  NF-kappa B signaling pathway
rno04380  Osteoclast differentiation
rno04611  Platelet activation
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno05169  Epstein-Barr virus infection
rno05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    367901 (Btk)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    367901 (Btk)
   04662 B cell receptor signaling pathway
    367901 (Btk)
   04664 Fc epsilon RI signaling pathway
    367901 (Btk)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    367901 (Btk)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    367901 (Btk)
  09163 Immune disease
   05340 Primary immunodeficiency
    367901 (Btk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    367901 (Btk)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     367901 (Btk)
Protein kinases [BR:rno01001]
 Non-receptor tyrosine kinases
  TEC family
   367901 (Btk)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 PH BTK SH3_9 SH3_2 SH3_3 Kinase-like SH3_10 ABC1 Pkinase_fungal Kdo Haspin_kinase SH3_4 Dicer_dsRBD DNApol3-delta_C
Other DBs
NCBI-GeneID: 367901
NCBI-ProteinID: NP_001007799
RGD: 1359683
Ensembl: ENSRNOG00000052407
UniProt: Q5S255
Position
X:complement(102016070..102055448)
AA seq 661 aa
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEK
ITCVETVVPEKNPPPERQIPVPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTE
ELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPG
SSHRKTKKPLPPTPEEDQILKKPLPPEPTAAPISTSELKKVVALYDYMPMNANDLQLRKG
EEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQE
GKEGGFIVRDSSKAGKYTVSVFAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPEL
INYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKY
GKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMA
NGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVS
DFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKIPY
ERFTNSETAEHIAQGLRLYRPHLASDRVYTIMYSCWHEKADERPSFKILLSNILDVMDEE
S
NT seq 1986 nt   +upstreamnt  +downstreamnt
atggctgctgtgatactggagagcatctttctgaagcgctcccagcagaaaaagaaaaca
tcacctttaaattttaagaagcgcctatttctcctgactgtgcacaaactttcatactat
gaatatgactttgaacgtgggagaagaggcagtaagaaaggttcaatagatgtcgagaag
atcacctgtgttgaaacagtagttcctgaaaaaaatcccccaccagaaagacagattcca
gttccgaggaggggtgaggagtccagtgaaatggaacagatttcaatcattgaaaggttc
ccgtacccatttcaggtcgtatatgatgaaggacctctctatgttttctccccaaccgaa
gagctgagaaaacgctggattcaccagctcaaaaatgtaatccggtacaatagtgacctg
gtgcagaaatatcatccttgcttctggattgatggacagtatctctgctgctctcagaca
gccaagaatgctatgggctgccaaattttggagaacaggaatggaagcttaaaacctgga
agttctcatcgaaaaacaaaaaagcctcttccccctaccccagaggaagatcagatcttg
aaaaagccactcccccctgagccaacagcagcaccaatctccacaagtgagctgaaaaag
gtcgtggccctttatgattatatgccaatgaatgcaaatgacttacaattgcgaaagggc
gaggagtattttatcctggaggagagcaacctaccatggtggcgagcacgagataaaaat
gggcaggaaggctatatccccagtaactatgtcaccgaagcagaggactccatagagatg
tatgagtggtattccaagcacatgactcgaagtcaagctgagcaacttctaaagcaagag
gggaaagaaggaggtttcattgtcagagactccagcaaagctggaaaatacactgtgtct
gtgtttgctaaatctacaggggagcctcaaggggtgatacgccattatgttgtgtgctcc
acacctcagagccagtattacctggctgagaagcaccttttcagcaccattcctgagctc
atcaactaccatcaacataactctgcaggcctcatatccaggctgaaatatcctgtatcg
aaacaaaacaaaaacgcgccttctacggcaggcctgggctatggatcatgggaaattgat
ccaaaggacttgaccttcttgaaggagcttgggactggacaatttggtgtcgtcaaatat
gggaagtggaggggccaatatgatgtggccatcaagatgatcagagaaggttccatgtct
gaggatgaattcattgaagaagccaaagtcatgatgaatctttcccatgagaagctagtg
cagttgtatggagtctgcaccaaacagcgccccatcttcatcatcactgaatacatggct
aatggctgcctcttgaactacctgagggagatgcggcaccgcttccagacacagcagctg
cttgagatgtgcaaagatgtctgtgaagcaatggaatacttggagtcaaagcagttcctt
catagagacctggcagctcgaaactgtctggtaaatgatcaaggagttgtgaaagtatct
gactttggcctgtctaggtatgttcttgatgatgaatacaccagctcggtaggctccaaa
tttccagtccggtggtctccaccagaagtgctcatgtatagcaaattcagcagcaaatct
gacatctgggcttttggggttctaatgtgggaaatttactccctggggaaaataccatat
gagagatttactaacagtgagacagcagaacacattgctcaaggcttacgtctctacagg
cctcatttggcatcagacagggtatataccatcatgtacagctgctggcatgagaaagca
gatgaacgtcctagtttcaaaattctcttgagtaacattctagatgtcatggatgaagaa
tcttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (18)   
   Pfam (18)   
All databases (49)   

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