KEGG   Rattus norvegicus (rat): 432361
Entry
432361            CDS       T01003                                 
Symbol
Nrg2
Name
(RefSeq) pro-neuregulin-2, membrane-bound isoform
  KO
K05456  neuregulin 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04012  ErbB signaling pathway
rno05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    432361 (Nrg2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    432361 (Nrg2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    432361 (Nrg2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rno04052]
    432361 (Nrg2)
Cytokines and neuropeptides [BR:rno04052]
 Cytokines
  Growth factors (RTK binding)
   432361 (Nrg2)
SSDB
Motif
Pfam: Neuregulin I-set Ig_3 ig Ig_2 Ig_6 V-set C2-set_2 EGF EGF_2
Other DBs
NCBI-GeneID: 432361
NCBI-ProteinID: NP_001129623
RGD: 1303302
Ensembl: ENSRNOG00000019093
UniProt: O35569
Position
18:complement(27890578..28072538)
AA seq 860 aa
MRQVCCSALPPPLEKARCSSYSYSDSSSSSSSNNSSSSTSSRSSSRSSSRSSRGSTTTTS
SSENSGSNSGSIFRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSML
LFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVL
DKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKE
VGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIR
IKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARK
CNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQK
RVLTITGICVALLVVGIVCVVAYCKTKKQRRQMHHHLRQNMCPAHQNRSLANGPSHPRLD
PEEIQMADYISKNVPATDHVIRREAETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLE
RSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLR
DSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQ
QPLLRHPAPPGPGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPED
DEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSG
CGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTR
ASSRHSRGPPTRAKQDSGPL
NT seq 2583 nt   +upstreamnt  +downstreamnt
atgcggcaggtttgctgctcagcgctgccgccgccactggagaaggctcggtgcagcagc
tacagctacagcgacagcagcagcagcagcagcagcaacaacagcagcagcagcaccagc
agcagaagcagcagcagaagcagcagcagaagcagcagaggcagcaccaccaccaccagc
agcagcgagaacagcggcagcaacagcggcagcatcttccgtcccgctgcgcccccagag
ccgcggccgcagccacagccgcagccccgcagccccgcagcccggagagccgccgcccgc
tcgcgagccgcagccgccggcggcatgaggcgcgacccggcccccggcttctcgatgctg
ctcttcggtgtgtcactcgcctgctactcgcccagcctcaagtccgtgcaggaccaggcg
tacaaggcacccgtggtggtggagggcaaggtacagggactggccccggcaggcggttcc
agctctaacagcacccgagagcctcccgcctcgggtcgggtggcgctggtgaaggtgctg
gacaagtggccgctccggagcggggggctgcagcgcgagcaggtgatcagcgtgggctcc
tgcgcgccgctcgaaaggaaccagcgctacatctttttcctggagcccaccgagcagccc
ttagtttttaagacagcctttgccccggtcgaccctaacggcaaaaacatcaagaaagag
gtgggcaagatcctgtgcactgactgcgcaacccggcccaagctgaagaagatgaagagt
cagacaggagaggtgggcgagaagcagtcgctcaagtgtgaggcggcggcggggaacccc
cagccctcctatcgatggttcaaggacggcaaggagctcaaccggagtcgtgacattcgc
atcaagtatggcaacggcagaaagaactcacggctacagttcaacaaagtgaaggtggag
gacgctggagagtacgtctgtgaggctgagaacatccttgggaaggacactgtgaggggc
cggctccatgtcaacagtgtgagcaccactctgtcgtcctggtcggggcacgcccggaag
tgcaatgagacagccaagtcctactgtgtgaatggaggcgtgtgctactacatcgaaggc
atcaaccaactctcctgcaaatgtccaaacggattcttcggacagagatgtttggagaaa
ctgcctttgcgattgtacatgccagatcctaagcaaaaggctgaggagctgtaccagaag
agagtcctgacaattaccggcatctgtgtggctctgctggtcgtgggcatcgtctgtgtg
gtcgcctactgcaagactaaaaaacagaggaggcaaatgcatcaccatctccggcagaac
atgtgtccggcccaccagaaccgaagcctggccaatgggcccagccaccctcggctggac
cctgaggagatccagatggcagattacatttccaaaaatgtgccagctacagaccatgtg
atccggagggaagctgagaccacattttctgggagccactcctgttcaccctctcaccac
tgttccacagccacacccacctccagccacagacatgagagccacacgtggagcttggaa
cgttcggagagcctgacctcggattcccagtcaggcatcatgctatcatcagtgggcacc
agcaagtgcaacagcccagcatgtgtggaggcacgggcacggagggcagcagcctacagc
caggaggagcgacgcagggctgccatgccaccctaccacgactccatagactcgctgcgt
gactccccacacagtgagaggtacgtgtcagccctgaccacgcccgcgcgcctttcgccc
gtggacttccactactcgctggccacccaggtgccgactttcgagatcacgtcgcccaac
tctgcccacgccgtgtcgctgccacccgcagcgcccatcagctaccgcctagcggagcag
cagccgctcctgcggcacccagcgccgcccggcccggggccagggcccggagcggacatg
cagcgcagctacgacagctactactacccggcggcggggcccgggccgcggcgcggcgcc
tgcgcgctgggaggcagtttgggcagcctgcccgccagccccttccgcatcccggaggac
gacgagtacgagaccacgcaggagtgcgcgcccccgccaccgccgcggccgcgcacgcgc
ggcgcgtcccgcaggacgtcggcggggccgcggcgctggcggcgctcccgcctcaacggg
ttggctgcgcagcgcgcacgcgcagcgcgggactcgctgtcgttgagcagcggttcgggc
tgcggctcggcgtcggcctcggacgacgatgcggacgacgcggacggggcgctggcggcc
gagagcacgcctttcctcggcctgcgagcggcgcacgacgcgctgcgctcggactcgccg
ccgctctgcccggcggcggacagcaggacttactactccctggacagccacagcacgcgc
gccagcagcagacacagccgggggccgcccacgagggcaaagcaggactccgggcccctc
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (15)   
   RefSeq(nuc) (9)   
   GenBank (3)   
   EMBL (3)   
Protein domain (10)   
   Pfam (10)   
All databases (48)   

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