KEGG   Rattus norvegicus (rat): 444984
Entry
444984            CDS       T01003                                 
Symbol
Dnmt3a
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 3A isoform 1
  KO
K17398  DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00270  Cysteine and methionine metabolism
rno01100  Metabolic pathways
rno04148  Efferocytosis
rno05206  MicroRNAs in cancer
Module
rno_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    444984 (Dnmt3a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    444984 (Dnmt3a)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    444984 (Dnmt3a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    444984 (Dnmt3a)
   03032 DNA replication proteins [BR:rno03032]
    444984 (Dnmt3a)
   03036 Chromosome and associated proteins [BR:rno03036]
    444984 (Dnmt3a)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     444984 (Dnmt3a)
Transcription factors [BR:rno03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    444984 (Dnmt3a)
DNA replication proteins [BR:rno03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    444984 (Dnmt3a)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    444984 (Dnmt3a)
SSDB
Motif
Pfam: ADD_DNMT3 ADDz_Dnmt3b DNA_methylase PWWP
Other DBs
NCBI-GeneID: 444984
NCBI-ProteinID: NP_001003958
RGD: 1303336
Ensembl: ENSRNOG00000026649
UniProt: Q1LZ53
Position
6:32507316..32621678
AA seq 908 aa
MPSSGPGDTSISSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESS
DTPKDPAVTTKSQPTAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTET
PPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRP
MPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEESQASGESQKVEEASP
PAVQQPTDPASPTVATTPEPVGADAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFS
WWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPM
YRKAIYEVLQVASSRAGKLFPACHDSDESDTGKAVEVQNKQMIEWALGGFQPSGPKGLEP
PEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVR
QKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGR
EVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSR
LQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASE
VCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLY
EGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKE
VSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGK
DQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAP
LKEYFACV
NT seq 2727 nt   +upstreamnt  +downstreamnt
atgccctccagcggccccggggacaccagcatctcctctctggagcgggaggatgatcga
aaggaaggagaggaacaggaggagaaccgtggtaaggaagagcgtcaggagcccagcgcc
acggcccggaaagtggggaggcctggccggaagcgcaagcacccaccggtggaaagcagt
gacacccccaaggacccagcggtgaccaccaagtctcagcccacagcccaggactctggg
ccctcagatctgctacccaatggagacttggagaagcggagtgaaccccaacctgaggag
gggagcccagctgcagggcagaagggtggggccccagctgaaggagagggaactgagacc
ccaccagaagcctccagagcagtggagaatggctgctgcgtaaccaaggaaggccgtgga
gcctctgcgggagagggcaaagaacagaagcagaccaacatcgaatccatgaaaatggag
ggctcccggggccgactgcgtggtggcttggggtgggagtccagcctccgtcagcggccc
atgccaagactcaccttccaggcaggggacccctactacatcagcaaacggaagcgggat
gagtggctggcacgttggaaaagggaggctgagaagaaagccaaggtgattgcagtaatg
aatgctgtggaggaaagccaggcctctggggagtcccagaaggtggaggaggccagccct
cctgcagtgcagcagcccacggaccctgcatctcccactgtggccaccacccctgagcca
gtaggggctgatgctggggacaagaatgctaccaaggcagctgatgacgagcccgagtat
gaggatggccggggctttggcattggagagctggtgtgggggaaactccggggcttctcc
tggtggccaggccgaattgtgtcttggtggatgacaggccggagccgagcagccgaaggc
actcgctgggtcatgtggttcggagatggcaaattctcagtggtgtgtgtcgagaagctc
atgcccctgagctccttctgcagtgcgttccaccaggccacctacaacaagcagcccatg
taccgcaaagccatctacgaagtcctccaggtggccagcagccgtgcagggaagctgttc
ccagcatgtcatgacagcgatgaaagtgacactggcaaggctgtggaggtgcagaacaag
cagatgattgagtgggcccttggcggcttccagccctctggtcccaaaggcctggagcca
ccagaagaggagaagaatccttacaaggaagtttacaccgacatgtgggtggagcctgag
gcagctgcttatgccccacccccaccagccaagaaacccagaaagagcacaacagagaaa
cccaaggtcaaggagatcattgatgaacgcacaagagaacggctcgtgtatgaggtgcgc
cagaagtgccgaaacatcgaggacatttgtatctcatgtgggagcctcaatgttaccctg
gagcacccactcttcattggtggaatgtgccagaactgtaagaactgcttcttggagtgt
gcttaccaatacgatgacgatgggtaccagtcctactgtaccatctgctgtggggggcgc
gaagtgctcatgtgtgggaacaacaactgctgcaggtgcttttgtgtggagtgtgtggat
ctcttggtggggccaggggctgcccaagcagccattaaggaagacccctggaactgctac
atgtgtgggcacaagggcacgtatgggctgctgcggagacgggaggactggccttctcga
ctccagatgttcttcgccaataaccacgaccaggaatttgaccccccgaaggtttaccca
cctgtgccagctgagaagaggaagcccatccgggtgctatctctctttgatgggattgct
acagggctcctggtgctgaaggacctgggcatccaagtggaccgctacatcgcctccgag
gtgtgcgaggactccatcacagtgggcatggtgcggcaccagggaaagatcatgtacgtc
ggggacgtccgcagcgtcacacagaagcatatccaggagtggggcccattcgatctggtg
attgggggcagtccctgcaatgacctctccatcgtcaaccctgcccgcaagggactttac
gagggcacgggccgcctcttctttgagttctaccgcctcctgcatgacgcgcggcccaag
gagggagatgatcgccccttcttctggctttttgagaatgtggtggccatgggcgttagt
gacaagagggacatctcgagatttcttgagtctaaccccgtgatgatcgacgccaaagaa
gtgtctgctgcacacagggcccgttatttctggggtaaccttcctggcatgaacaggcca
ttggcatccactgtgaatgataagctggagttgcaagagtgtctggaacacggcagaata
gccaagttcagcaaagtgaggaccattaccaccaggtcaaactccataaagcagggcaaa
gaccagcatttccctgtcttcatgaatgagaaggaagacatcctctggtgcactgaaatg
gaaagggtgtttggcttccctgtccactacacagacgtctccaacatgagccgcttggcg
aggcagagactgctgggccgatcgtggagcgtgccagtcatccgccacctcttcgctccg
ctgaaggaatattttgcttgtgtgtaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (18)   
   RefSeq(nuc) (12)   
   GenBank (3)   
   EMBL (3)   
Protein domain (4)   
   Pfam (4)   
All databases (59)   

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