KEGG   Rattus norvegicus (rat): 445442
Entry
445442            CDS       T01003                                 
Symbol
Thbs1
Name
(RefSeq) thrombospondin-1 isoform 1 precursor
  KO
K16857  thrombospondin 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04115  p53 signaling pathway
rno04145  Phagosome
rno04148  Efferocytosis
rno04151  PI3K-Akt signaling pathway
rno04350  TGF-beta signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04820  Cytoskeleton in muscle cells
rno05144  Malaria
rno05165  Human papillomavirus infection
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05219  Bladder cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    445442 (Thbs1)
   04350 TGF-beta signaling pathway
    445442 (Thbs1)
   04151 PI3K-Akt signaling pathway
    445442 (Thbs1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    445442 (Thbs1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    445442 (Thbs1)
   04148 Efferocytosis
    445442 (Thbs1)
  09143 Cell growth and death
   04115 p53 signaling pathway
    445442 (Thbs1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    445442 (Thbs1)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    445442 (Thbs1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    445442 (Thbs1)
   05205 Proteoglycans in cancer
    445442 (Thbs1)
  09162 Cancer: specific types
   05219 Bladder cancer
    445442 (Thbs1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    445442 (Thbs1)
  09174 Infectious disease: parasitic
   05144 Malaria
    445442 (Thbs1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    445442 (Thbs1)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    445442 (Thbs1)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Opsonins
    445442 (Thbs1)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   445442 (Thbs1)
SSDB
Motif
Pfam: TSP_C TSP_3 TSP_1 TSP1_spondin VWC EGF_3 cEGF TSP1_ADAMTS Laminin_G_2 Laminin_G_3 TSP1_CCN EGF Laminin_G_1
Other DBs
NCBI-GeneID: 445442
NCBI-ProteinID: NP_001013080
RGD: 1588455
Ensembl: ENSRNOG00000045829
UniProt: Q71SA3
Position
3:125510250..125525402
AA seq 1170 aa
MELLRGLGVLFLLHVCGSNRIPESGGDNGVFDIFELIGGARKVPGRRLVKGQDLSSPAFR
IENANLIPPVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNSGQIFSVV
SNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELD
VPIQSIFTRDLANVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTNVLL
TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELRGLRTIVTTLQDSIRK
VTEENRELASELRRPPLCFHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQT
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE
TKACKKDACPINGGWSPWSLWDICSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDVTENQV
CNKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACF
NHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKN
AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
HNPDQADTDNNGEGDACAVDIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH
NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN
DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENVDISETDFRRF
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD
KTYAGGRLGLFVFSQEMVFFSDMKYECRDS
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggagctcctcaggggactaggcgtcctgttcctgttgcatgtgtgtggaagcaaccgc
attccagagtctgggggagacaatggtgtgttcgacatttttgaactcattggaggtgcc
cgcaaggttccgggtcgccgactggtgaagggccaagatctatccagccccgccttccgg
atcgagaatgccaacctgatcccccctgtgccagatgacaagttccaagacctactggac
gctgtgtgggccgacaaaggcttcatcttcctggcttccttgaggcagatgaagaagact
cggggcacactcctggccgtggaacggaaagacaattctggccagatcttcagtgtggtc
tccaatggcaaagccggcaccctcgatctgagtctgagcctgcccgggaagcagcaagtg
gtgtcagtggaggaagctctcctggccactggccagtggaagagcatcacgctgtttgtc
caagaagacagggcccagctctacattgactgtgacaagatggagagcgcagagctggat
gttcccatccagagcatcttcaccagggatttggccaatgtcgccaggctccgagtcgca
aagggagatgtcaatgacaattttcagggggtgctgcagaatgtgaggtttgtctttgga
accaccccagaagacattctcaggaacaaaggctgctccagttctaccaacgtccttctc
acccttgacaacaacgtggtgaacggttccagccctgccatccgcaccaactacatcggc
cacaaaacaaaggacctccaagccatctgtggcctctcctgtgacgaactatccagcatg
gtcctggaactgaggggcctgcgtaccatcgtgaccacgctacaggacagcattcgaaaa
gtgacggaagagaacagagagctggctagcgagctgaggcggcctcccctctgcttccac
aatggagtccaatacaggaacaacgaggagtggactgtagatagttgcacagagtgtcac
tgccagaactcagttaccatctgcaaaaaggtgtcctgtcccatcatgccctgctccaat
gccacagttcctgatggtgaatgctgcccacggtgctggcccagtgactctgctgacgat
ggctggtctccctggtctgagtggacctcttgctctgccacctgtggcaatgggattcag
caacgtggtcgctcctgtgacagcctcaacaacagatgtgagggctcttcagtacagacg
aggacctgccacattcaggagtgcgacaaaagatttaaacaggatggtggttggagtcac
tggtccccgtggtcgtcctgttctgtgacctgtggtgacggtgtgatcacgaggatccga
ctctgcaactcccccagcccccagatgaacgggaagccctgtgaaggtgaagctcgggag
accaaagcctgcaagaaggacgcctgcccaatcaatggaggctggagtccctggtcacta
tgggacatctgctctgtcacctgtggaggaggagtacagagacgtagccgactctgcaac
aaccccacaccccagtttggaggcaaagactgtgttggtgatgtgacggaaaatcaagtt
tgcaacaagcaggactgtccgattgatggatgcctgtccaatccctgctttgctggtgcc
aagtgtacgagctatcctgatggtagctggaaatgtggtgcgtgtcctcctggctacagt
ggaaatggtatccagtgcaaagacgtcgacgagtgcaaagaagtgcctgatgcttgcttc
aatcacaacggagaacatcggtgcaagaacacagatcctggctacaactgcctgccctgc
ccaccacgattcaccggctcacagcccttcggcagaggtgtcgaacacgctatggccaac
aaacaggtgtgcaaaccccgaaacccctgcaccgacgggacacacgactgcaacaagaac
gccaagtgcaactacctgggtcactacagcgaccccatgtaccgctgtgagtgcaagcct
ggctacgcaggcaatggcatcatttgcggagaggacacagaccttgacggctggcctaat
gaaaacctggtgtgtgtggccaacgcaacttaccactgcaaaaaggacaactgccccaat
cttcccaattcggggcaggaagactatgacaaggatgggattggcgatgcctgtgatgac
gatgatgacaacgacaagattcctgatgacagggacaactgtccattccattacaaccca
gcccagtatgactatgacagagatgatgtgggagaccgctgtgacaattgcccctacaac
cacaaccctgaccaggcagacacagacaacaatggggagggagatgcctgcgctgtggac
atcgatggggatggaatcctcaatgaacgagacaactgccagtatgtttacaacgtggat
cagagggacacggacatggatggggttggagaccagtgtgacaactgccccctggaacac
aatccagaccagctggactctgactcggaccgcataggggacacctgtgacaacaatcag
gacatcgatgaggatggccatcagaacaacctggacaactgtccctatgtgcccaatgcc
aaccaggccgaccacgataaagatggtaaaggagacgcctgtgaccatgacgatgacaac
gacggcatccctgatgacagagacaactgcaggctggtgcccaatcctgaccagaaggac
tctgatggtgatggccgaggcgatgcctgcaaagacgactttgaccatgacaatgtgcca
gacattgatgacatctgtcctgagaatgttgacatcagtgaaaccgatttccgccgattc
cagatgattcctctagatcccaaaggaacctcccaaaatgaccctaactgggttgtccgc
catcagggcaaagaacttgtccagactgtaaactgtgaccctggacttgctgtaggttat
gatgagtttaatgccgtggacttcagtggtaccttcttcatcaacactgagagggatgac
gactatgctggctttgttttcggctaccagtccagcagccgcttctacgttgtgatgtgg
aaacaagtcacccagtcctactgggacaccaaccccacaagggctcagggatactcaggc
ctgtctgtaaaggttgtaaactccaccactggccccggcgagcacctgcggaatgcactg
tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacatt
ggctggaaagatttcactgcatacagatggcgtctcagccacaggccaaagaccggtttt
atcagagtggtgatgtatgaaggaaagaaaatcatggctgactcaggacccatctatgac
aaaacctacgctggcggtagactaggcctgttcgtcttctctcaagaaatggtgttcttc
tcggacatgaaatacgagtgccgagactcctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (13)   
   Pfam (13)   
All databases (46)   

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