KEGG   Rattus norvegicus (rat): 494500
Entry
494500            CDS       T01003                                 
Symbol
Gsta3
Name
(RefSeq) glutathione S-transferase alpha-5 isoform 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    494500 (Gsta3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    494500 (Gsta3)
   00982 Drug metabolism - cytochrome P450
    494500 (Gsta3)
   00983 Drug metabolism - other enzymes
    494500 (Gsta3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    494500 (Gsta3)
   05204 Chemical carcinogenesis - DNA adducts
    494500 (Gsta3)
   05207 Chemical carcinogenesis - receptor activation
    494500 (Gsta3)
   05208 Chemical carcinogenesis - reactive oxygen species
    494500 (Gsta3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    494500 (Gsta3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    494500 (Gsta3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    494500 (Gsta3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    494500 (Gsta3)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     494500 (Gsta3)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   494500 (Gsta3)
SSDB
Motif
Pfam: GST_C GST_C_3 GST_N GST_N_2 GST_C_2 GST_N_3
Other DBs
NCBI-GeneID: 494500
NCBI-ProteinID: NP_001009920
RGD: 1591980
Ensembl: ENSRNOG00000056847
UniProt: P46418 A6JJ95
Position
9:31154989..31180653
AA seq 221 aa
MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEENFLKTRDDLARLRSDGSLMFEQVPMVEI
DGMKLVQTKAILNYIATKYNLYGKDMKERALIDMYAEGVADLELMVLYYPYMPPGEKEAS
LAKIKDKARNRYFPAYEKVLKSHGQDYLVGNKLSRADVSLVELLYHVEEMDPGIVDNFPL
LKALRTRVSNLPTVKKFLQPGSQRKPFDDEKCVESAKKIFS
NT seq 666 nt   +upstreamnt  +downstreamnt
atgccggggaagccagtccttcactacttcgatggcagggggagaatggagcccatccgg
tggctcctggctgcagctggagtagagtttgaagaaaattttctgaaaactcgggatgac
ctggccaggttaagaagtgatgggagtttgatgtttgaacaagtgcccatggtggagatt
gacgggatgaagctggtgcagaccaaagccattctcaactacattgccaccaaatacaac
ctctatgggaaggacatgaaggagagagccctcatcgacatgtatgcagaaggtgtggcc
gatctggagttgatggttctctattacccctacatgccccctggggagaaagaggcgagt
cttgccaagatcaaggacaaagcaaggaaccgttacttccctgcctatgagaaggtgttg
aagagccacggacaagattatctcgttggcaacaagctgagcagggctgatgtttccctg
gttgaacttctctaccatgtggaagagatggacccaggcattgtggacaacttccctctg
ctaaaggccctgagaaccagagtcagcaacctccccacagtgaagaaatttcttcagcct
ggcagccagaggaagccttttgatgatgagaaatgtgtagaatcagcgaagaagatcttc
agttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
Protein domain (6)   
   Pfam (6)   
All databases (141)   

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