KEGG   Rattus norvegicus (rat): 497811
Entry
497811            CDS       T01003                                 
Symbol
Xdh
Name
(RefSeq) xanthine dehydrogenase/oxidase
  KO
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno00232  Caffeine metabolism
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01232  Nucleotide metabolism
rno04146  Peroxisome
Module
rno_M00958  Adenine ribonucleotide degradation, AMP => Urate
rno_M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    497811 (Xdh)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    497811 (Xdh)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    497811 (Xdh)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    497811 (Xdh)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    497811 (Xdh)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.4  xanthine dehydrogenase
     497811 (Xdh)
   1.17.3  With oxygen as acceptor
    1.17.3.2  xanthine oxidase
     497811 (Xdh)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   497811 (Xdh)
SSDB
Motif
Pfam: MoCoBD_2 MoCoBD_1 FAD_binding_5 Ald_Xan_dh_C Fer2_2 CO_deh_flav_C Fer2
Other DBs
NCBI-GeneID: 497811
NCBI-ProteinID: NP_058850
RGD: 62043
Ensembl: ENSRNOG00000007081
UniProt: P22985
Structure
Position
6:27282319..27344022
AA seq 1331 aa
MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR
LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIV
MSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM
NQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAST
MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGA
SCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL
NPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAF
KQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEE
LLQSVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDP
TFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYE
NELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEV
TCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLK
KGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML
GVPDNRIVVRVKRMGGGFGGKETRSTVVSTAVALAAHKTGRPVRCMLDRDEDMLITGGRH
PFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRI
CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLE
GFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGAL
VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAAS
ASADLNGQAVYEACQTILKRLEPFKKKKPNGPWEAWVMDAYTSAVSLSATGFYKTPNLGY
SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG
EPPLFLASSIFFAIKDAIRAARAQHGDNAKQLFQLDSPATPEKIRNACVDQFTTLCVTGV
PENCKSWSVRI
NT seq 3996 nt   +upstreamnt  +downstreamnt
atgactgcggatgagttggtcttctttgtgaatggcaaaaaggtggtggagaaaaatgcg
gaccctgaaacaacacttctggtctacctgagaagaaagttggggctatgtgggaccaag
cttggctgtggagaaggtggctgtggggcatgcaccgtgatgatctccaagtatgaccgt
cttcagaacaagattgttcatttttctgtcaatgcctgcttggctcccatctgctccttg
caccatgttgctgtgaccaccgtggaaggcataggaaacacccagaagctgcatcctgta
caggagagaattgccagaagccatggttcccagtgtgggttctgcactcctggcattgtc
atgagtatgtacacactgctccggaaccagcctgagcctactgttgaggagatcgagaat
gccttccaaggaaacctctgtcgctgtacaggctacagacccatcctccagggattccgg
acctttgccaaggatggtgggtgctgtggagggagtggaaacaacccaaactgctgtatg
aaccagacgaaagaccaaacggtttctctctcaccttctttattcaacccagaggatttc
aaacctttagatcccacgcaagagcccatcttccccccagagttgctgaggctgaaagac
actccccagaagaagctgcgttttgaaggggaacgtgtgacctggatccaggcttcaact
atggaggagctgcttgacctgaaagctcagcaccctgatgccaagctggtggtgggaaac
acagagataggcattgaaatgaaatttaagaatatgctatttcctctgatcgtctgccca
gcctggatccctgaactgaattcagtggtgcatgggcctgagggaatctccttcggagct
tcttgcccccttagcttggtggaaagtgtcctggcggaggagattgctaaacttccagag
caaaagacagaggtgttcagaggcgtgatggagcagctgcgctggtttgccggcaagcag
gtcaagtccgtggcgtccatcggagggaacatcatcactgccagccccatctctgacctc
aaccctgtgttcatggccagtggagccaagctgactctggtgtctagaggtaccaggaga
actgttcggatggatcataccttcttccctggctacagaaagactctgctcagaccagag
gagatattgctgtccatcgagatcccctatagcaaggagggagagtttttctcagccttc
aagcaggcctccaggagggaagatgacattgccaaggtgactagtggcatgagagtcctg
ttcaaaccggggaccattgaagtgcaggaactgtccctttgcttcggagggatggccgac
agaactatctcagccctcaagaccactccgaagcagctatcgaagtcctggaatgaggag
ctgctgcagagcgtgtgtgccggcttggcagaggagctgcacctggcccccgatgcccct
ggtggtatggtggaattccggcgcaccctcaccctcagcttcttcttcaagttctacctg
acagtgctccagaagctgggcagagcggaccttgaggatatgtgtggtaaactggacccc
acctttgccagtgccaccctgctctttcagaaggaccctccagctaatgtccagcttttc
caagaggtgccaaaggatcagtctgaggaggacatggtgggccggcccctgcctcacctg
gcggcaaacatgcaggcatcgggagaggccgtgtactgtgatgacattccccgctatgag
aatgagctctctctcaggctggtcaccagcacccgggcgcatgctaaaatcacgtccatc
gacacttcagaagccaagaaggtgccagggtttgtttgcttcctcaccgcagaggatgtc
cctaatagtaatgcaaccggccttttcaatgatgaaactgtctttgcgaaggatgaggtt
acttgtgttgggcacatcattggtgctgtggtcgctgacaccccagaacacgcacagaga
gctgcgagaggggtgaaaatcacctatgaagatcttccagccattatcacaatccaggat
gctataaacaacaactccttttatggctctgagataaaaattgagaaaggagatctcaag
aaaggcttttcagaagctgacaatgttgtctcaggagagttgtatatcggtggccaggag
cacttctacctggagaccaactgcaccattgccgtgccaaaaggcgaggcaggcgagatg
gagctgttcgtgagcacacagaacaccatgaaaacccagagctttgttgcaaaaatgttg
ggcgttccggacaacagaatcgtagtccgagtgaagaggatgggtggaggctttggaggg
aaggagacccggagcactgtggtgtccacagcagtggccttggctgcacacaagactggc
cggcccgtacgttgcatgttggaccgagatgaggacatgctgataactggtggcagacat
cccttcctggctaaatacaaggttggcttcatgaagactgggactgtagtggctctcgag
gtggctcacttcagcaatggtggtaacactgaggatctctctcggagtataatggaacga
gctttgttccacatggataacgcctataagatccccaacattcgaggcactgggaggatt
tgcaagactaatctgccctccaacacagccttcagaggttttgggggtcctcaggggatg
ctaatcgcagaatactggatgagcgaggtcgccataacctgtgggctgcctgcagaggag
gtacggaggaaaaacatgtacaaagaaggggacctgactcacttcaaccagaagctggag
gggttcaccttgcccaggtgctgggatgaatgcatcgccagctctcagtatcttgctcgc
aagagggaagtggagaaattcaacagggagaattgttggaaaaagagagggctgtgtata
atcccaactaagtttggaataagctttacacttccttttctgaaccagggaggcgctctg
gttcacgtgtacactgatggttcggtgctgttgacccatggagggactgagatgggccaa
ggccttcacaccaagatggttcaggtggccagcagagctctgaaaatccccacctccaag
attcatataagtgagacaagcactaacaccgtccccaacacttctcccacagctgcctct
gccagtgctgacctcaatggacaggctgtttatgaagcatgccagaccatactgaaaagg
ctggaacctttcaagaagaagaaacccaacggcccctgggaggcatgggtgatggacgcc
tatacgagcgcagtgagtttgtccgcgactggattttataagacacccaaccttggctac
agctttgagacaaactccggaaatcccttccactatttcagttatggggtggcttgctct
gaagtagaaattgactgcttaacaggggatcataagaatctccgtacggatatcgtcatg
gatgttggttccagcttgaatcctgccattgatattggacaagtagagggggcatttgtc
cagggccttggtctcttcactatggaggagctgcactactcccctgaggggagcctgcat
actcgtggccccagtacctacaaaatccctgcgtttggtagcatccccattgagttcaga
gtatccctactccgggactgccccaacaagagggccatctatgcatccaaggctgttggg
gagccacctcttttcctggcttcctctatcttctttgccatcaaagatgccattcgtgca
gctcgagctcagcacggagataacgcaaaacaacttttccagctagacagccctgccact
ccggagaagatccgaaacgcctgtgtggaccagttcaccaccctgtgtgtcactggagta
ccagaaaactgtaaatcctggtctgtgaggatctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (2)   
   KEGG REACTION (13)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
3D Structure (14)   
   PDB (14)   
Protein domain (7)   
   Pfam (7)   
All databases (85)   

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