KEGG   Rattus norvegicus (rat): 500052
Entry
500052            CDS       T01003                                 
Symbol
Hyal5
Name
(RefSeq) hyaluronidase PH-20
  KO
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00531  Glycosaminoglycan degradation
rno01100  Metabolic pathways
rno04142  Lysosome
Module
rno_M00076  Dermatan sulfate degradation
rno_M00077  Chondroitin sulfate degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    500052 (Hyal5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    500052 (Hyal5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:rno02042]
    500052 (Hyal5)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    500052 (Hyal5)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:rno00537]
    500052 (Hyal5)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     500052 (Hyal5)
Bacterial toxins [BR:rno02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   500052 (Hyal5)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Enzymes
   500052 (Hyal5)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:rno00537]
 Enzymes
  500052 (Hyal5)
SSDB
Motif
Pfam: Glyco_hydro_56
Other DBs
NCBI-GeneID: 500052
NCBI-ProteinID: NP_001019492
RGD: 1566275
Ensembl: ENSRNOG00000039466
UniProt: F7FB21 Q5BK36
Position
4:54306643..54378272
AA seq 526 aa
MRVLCFKHSFFGSLLESSGLPQTLLVFLLIRCCLTVDFRAPPLIPNVPFLCAWNAPTESC
ATRFNQPLDLSLFSLVGSPRKTAIGHPVTIFYSDRLGLYPHIDEMHTAFHGGIPQLGSLK
SHLEIAKGDIHHYMPIDNVGLAVIDWEDWRPTWSRNWKFKDIYRNKSIEFVQQQNTQLNL
TEAVKRAKQEFEEAARNFMEQTLKLGKLLRPNHLWGFYLFPDCYNNNFQDANYKGDCPDI
EKQRNDALFWIWKESTALYPSIYLKSSLKSSPLAALYVRNRVQEAIRMSKVKDPHNPLPI
FVYFRPVFTDLTFQYLEQDDLVNTIGETVALGASGIVMWGTLNLSQTMKSCMNLHDYLKT
TLNPYIINVTLAAKMCSQTLCQNQGICSRKDWNSNDYLHLSPRNFQIHFIKHGKYEIIGS
PTLDDLQYFSKNFRCSCFSNLDCKERVDINHVSRVNVCTLEDICINSLVISDRSKLHDNW
DHLYFANDKQSGITSSATVSPCVPRKDVSGYLFVLSLYSRHLKYSL
NT seq 1581 nt   +upstreamnt  +downstreamnt
atgcgagtgttgtgttttaaacactccttctttgggagccttcttgagtccagtggacta
ccccagactctattagtcttccttttgattcgatgttgcttgactgtggattttagggca
cccccacttatccctaatgtgcctttcctctgtgcctggaatgccccaactgagtcttgt
gccacgaggtttaatcagccactagatcttagtctgttctctttagtaggaagccccaga
aaaactgccataggtcatcctgtcacaatattttattctgatcgtctgggtctctatcct
cacatagatgaaatgcacacagcttttcatggaggtataccccagctggggtctctaaaa
tctcatttggaaatagctaagggtgacatccatcattacatgccaatagacaatgtgggc
ttggctgtcattgactgggaagactggcggcctacctggtcaagaaactggaaattcaag
gatatttacaggaataagtctattgagttcgtccagcaacaaaacacacaacttaatttg
acagaagctgtcaagagggctaaacaagaatttgaagaggcagcaaggaattttatggaa
cagactttaaaattgggaaaattacttcgtccaaatcacttatggggtttttatcttttt
cctgattgttataacaacaattttcaagatgccaattacaaaggagattgccctgatata
gaaaagcaaaggaatgatgctctcttctggatatggaaggaaagcacagccctgtaccca
tccatctatttgaagagcagcttaaagtcatccccactggcagcactctacgtcagaaat
cgcgtacaagaagccattcgcatgtctaaagtaaaagaccctcataatccacttcctatt
tttgtatatttccgccctgtctttactgacctaactttccagtatctggaacaggatgac
cttgtgaatacaattggtgaaacagttgctctgggtgcctctggaatagtaatgtgggga
actcttaatttatcacaaactatgaaatcttgtatgaacttacatgattatttgaagacc
accctgaatccttatataatcaatgtcacccttgcagccaaaatgtgtagccaaacactt
tgccagaatcaaggcatatgttcgaggaaagattggaattcgaatgactatctacacttg
agccctcggaattttcagattcattttataaaacatggaaagtatgaaatcattggcagt
cccactcttgatgatctgcagtatttttccaaaaacttccgttgcagctgtttctccaac
ttggactgtaaggagagagttgacataaaccatgtgagcagggtcaatgtgtgtactctt
gaagacatttgcattaattcccttgtaatttcagaccgtagtaagctacatgacaactgg
gatcacctttattttgctaatgacaaacagtcaggtattacatcatctgccacagtgagt
ccatgtgtgccaagaaaagatgtcagtgggtacctctttgttctctctctctattcacgg
catttgaaatattcactatag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   RefSeq(pep) (3)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (37)   

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