KEGG   Rattus norvegicus (rat): 500985
Entry
500985            CDS       T01003                                 
Symbol
Cbl
Name
(RefSeq) E3 ubiquitin-protein ligase CBL
  KO
K04707  E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04012  ErbB signaling pathway
rno04120  Ubiquitin mediated proteolysis
rno04144  Endocytosis
rno04910  Insulin signaling pathway
rno05100  Bacterial invasion of epithelial cells
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    500985 (Cbl)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    500985 (Cbl)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    500985 (Cbl)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    500985 (Cbl)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    500985 (Cbl)
   05205 Proteoglycans in cancer
    500985 (Cbl)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    500985 (Cbl)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    500985 (Cbl)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    500985 (Cbl)
   04121 Ubiquitin system [BR:rno04121]
    500985 (Cbl)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     500985 (Cbl)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    500985 (Cbl)
Ubiquitin system [BR:rno04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   CBL proteins
    500985 (Cbl)
SSDB
Motif
Pfam: Cbl_N Cbl_N3 Cbl_N2 zf-C3HC4 zf-C3HC4_3 Prok-RING_4 UBA zf-RING_2 zf-C3HC4_2 zf-RING_UBOX zf-RING_5 zf-C3HC4_4
Other DBs
NCBI-GeneID: 500985
NCBI-ProteinID: NP_001406884
RGD: 1561386
Ensembl: ENSRNOG00000008444
Position
8:complement(53384656..53468067)
AA seq 914 aa
MAGNVKKSSGAGGSGSGGSGAGGLIGLMKDAFQPHHHHHHHLSPHPPCTVDKKMVEKCWK
LMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTVLSRYEGKMETLGENEYFRVFMEN
LMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRI
TKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEF
DIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLG
QWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHI
KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRC
EIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDSLFMMKELAGAKVERP
SSPFSMAPQASLPPVPPRLDLLQQRAPVPASTSVLGTASKASSSSLHKDKPLPIPPTLRD
LPPPPPPDRPYSVGTETRPQRRPLPCTPGDCPSRDKLPPVPSSRPGDSWLSRPIPKVPVA
TPNPGDPWNGRELTNRHSLPFSLPSQMEPRADVPRLGSTFSLDTSTTMNSSPVAGPESEH
PKIKPSSSANAIYSLAARPLPVPKLPPGEQGDSEEDTEYMTPTSRPVGVQKPEPKRPAET
AQSSRACDCDQQIDSCTYEAMYNIQSQALSVAENSACGEGNLATAHTSTGPEESENEDDG
YDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGEPTNFNEGSQVPERPPKPFPRRINSE
RKASSYQQGGGAMANPAAAAPSPQLSSEIERLMSQGYSYQDIQKALVIAHNNIEMAKNIL
REFVSISSPAHVAT
NT seq 2745 nt   +upstreamnt  +downstreamnt
atggccggcaacgtgaagaagagctcgggcgccggcggcagcggctctgggggctccgga
gcgggcggcctgatcgggctcatgaaggacgccttccagccgcaccaccaccaccaccac
cacctcagcccgcaccctccctgcacggtggacaagaagatggtggagaagtgctggaag
ctcatggacaaggtggtgcggttgtgtcaaaacccaaagctggctctcaagaacagccca
ccgtatatcttagacctgctgcctgacacctaccagcacctccgcactgtcctgtcgaga
tatgaggggaagatggagacgcttggagagaatgagtatttcagggtgttcatggagaat
ttgatgaagaaaactaagcagaccatcagcctcttcaaggagggaaaagaaaggatgtat
gaggagaattcccagcctaggcgaaacctaaccaagttatccctgatcttcagccacatg
ctggcagaactgaaaggcatctttccaagcggactcttccaaggagacacttttcggatc
actaaagcagacgctgcagagttctggagaaaagcttttggggaaaagacgatagtccct
tggaagagctttcgacaggccctgcatgaagtgcatcccatcagttctgggctggaggcc
atggctttgaagtccactattgatctgacctgcaatgattatatttctgtttttgaattt
gatatttttacacggctgtttcagccctggtcctctttgctcagaaattggaacagcctt
gctgtaactcaccctggctacatggctttcctgacgtatgatgaagtgaaagctcggctc
cagaagttcatccacaaacccggcagttacatctttcggctgagctgtactcgtttgggt
cagtgggctattgggtacgttacagctgatgggaacatcctgcagacaatcccacacaat
aaaccgctcttccaagcactgattgatggcttcagggaaggcttctatttgtttcctgat
ggaagaaatcaaaatcctgacctgacaggtttatgtgaaccaacccctcaagatcatatc
aaagtcacccaggaacaatatgaactatactgtgaaatgggctccacatttcaactatgt
aagatatgtgctgagaatgataaggatgtgaagattgagccctgtggacacctcatgtgc
acgtcctgcctcacatcgtggcaggaatcagaaggtcaaggctgtcctttttgccgatgt
gaaatcaaaggtactgagcccatcgtggtggatccatttgaccccagaggcagtggcagt
ctattaaggcaaggagcggaaggtgctccttccccaaattatgatgatgatgatgatgaa
cgagctgatgattctctcttcatgatgaaggagttggcaggtgccaaggtggaaaggcct
tcctctccattctccatggccccacaagcttcccttcctccagtgccaccaagacttgac
cttctacagcagcgagcacctgttcctgccagcacctctgttctggggactgcttccaag
gcttcttctagctcccttcataaggacaaaccattgccaatacctcctacgcttcgagat
cttcctccaccaccccctccagaccggccttactctgttggaacagaaacaaggcctcag
agacgccccctgccttgtactccaggcgactgtccatctagagacaaactgccccctgtc
ccctctagccgcccaggggactcatggttgtctcggccaatccctaaagtaccagtagcg
actccaaaccctggtgatccttggaatgggagagaattgaccaatcggcactcacttcca
ttctcattgccctcacaaatggaacccagagcagatgttccaaggcttggaagcacattt
agtctggatacctccacgactatgaatagcagcccagtagcaggtccagagagtgagcac
ccaaaaatcaagccttcctcatccgccaatgccatttactctctggctgccaggcctctt
cctgtgccaaaactgccacctggggagcaaggggacagtgaagaagacacggaatatatg
actcccacgtctaggcctgtaggggttcagaagccagagcccaaacggcctgcagagaca
gcgcagagttcacgagcctgtgactgtgaccagcagattgacagctgcacatacgaagca
atgtataacattcagtcccaagcactctccgtagcagagaacagtgcctgtggagaaggg
aatttggccacagcccacaccagtactggcccggaggagtcagaaaacgaggatgatggc
tatgatgtaccgaagcctcctgtgccagctgtactggcccgccggaccctgtctgacatc
tccaatgccagctcctcctttggctggttatctttggatggcgaacccacaaacttcaat
gagggttcccaagttcctgagcggccccccaaaccattccctcggagaatcaactcagaa
cgaaaagcaagtagctatcaacaaggcggaggtgccatggctaaccctgcagccgccgcc
ccctcaccgcagctctcaagcgagattgaacgcctcatgagtcagggctattcctaccag
gacattcagaaagcgttggtcattgcccacaacaacattgagatggccaaaaacatcctc
cgggaattcgtttctatttcttctcctgcccatgtagccacctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (12)   
   Pfam (12)   
All databases (49)   

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