KEGG   Rattus norvegicus (rat): 501110
Entry
501110            CDS       T01003                                 
Symbol
Gsta6
Name
(RefSeq) glutathione S-transferase A6
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    501110 (Gsta6)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    501110 (Gsta6)
   00982 Drug metabolism - cytochrome P450
    501110 (Gsta6)
   00983 Drug metabolism - other enzymes
    501110 (Gsta6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    501110 (Gsta6)
   05204 Chemical carcinogenesis - DNA adducts
    501110 (Gsta6)
   05207 Chemical carcinogenesis - receptor activation
    501110 (Gsta6)
   05208 Chemical carcinogenesis - reactive oxygen species
    501110 (Gsta6)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    501110 (Gsta6)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    501110 (Gsta6)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    501110 (Gsta6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    501110 (Gsta6)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     501110 (Gsta6)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   501110 (Gsta6)
SSDB
Motif
Pfam: GST_C_3 GST_N GST_C GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 501110
NCBI-ProteinID: NP_001019532
RGD: 1565402
Ensembl: ENSRNOG00000033402
UniProt: Q6AXY0
Position
9:complement(31239670..31297809)
AA seq 222 aa
MAEKPLFHYDEARGRMESVRWLLAAAGVEYEEKFIHTNEDLEKLRSDGVLMFQQVPMVEV
DGMKLVQTRAIMNYFSSKYNLYGKDMKERALIDMYSEGLADLNEMFILYPFDPPGVKEAN
IALMKEKATNRYFPAFEKVFESHGQDYLVGNKLSKADVHLVEMIYNMEELDTNILANFPL
LQALKTRISDMPTIKKFLQPGSQRQPPVDEKSIQKTRKIFKF
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcagagaagcctttatttcattatgatgaggcccggggtagaatggagtctgtgcgg
tggctattggctgcagctggagtagagtatgaagagaagtttatacacactaatgaagac
ttggagaagttaagaagtgatggagttctgatgttccagcaagtgcccatggtggaggtt
gatgggatgaagctggtgcagaccagagccattatgaactatttttccagcaaatacaat
ctctatgggaaggacatgaaggagagagccctcatcgatatgtattcggaagggttggca
gatttgaatgagatgtttattctctacccatttgacccacctggagtcaaagaagcaaat
atcgccctgatgaaagagaaagcaacaaaccgttactttcctgcctttgaaaaggtgttt
gagagtcatggacaggactacctcgttgggaacaagctaagcaaggctgatgttcacctg
gttgaaatgatctacaatatggaagaactagataccaacattttagccaactttcctcta
ctgcaggctctgaaaacccgaatcagcgacatgcccaccataaagaagtttctgcagcct
ggcagccaaaggcagcctcctgttgatgagaaaagtatacaaaagacaaggaagattttc
aagttttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (12)   
   RefSeq(nuc) (6)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (115)   

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